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sparseSingleCell

PoC on the application of Sparse functional principal component analysis (S-FPCA) for the analysis of single-cell chromatin accessibility data.

  • Proof of concept preprint

Madrigal P, Dai X, Hadjipantelis PZ (2018) Sparse functional data analysis accounts for missing information in single-cell epigenomics. bioRxiv 504365. DOI: 10.1101/504365

  • Minireview

Cremona MA, Xu H, Makova KD, Reimherr M, Chiaromonte F, Madrigal P (2019) Functional data analysis for computational biology. Bioinformatics 35, 3211-3213. DOI: 10.1093/bioinformatics/btz045