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bug post-optimization analysis #1

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EliseoMolina opened this issue Nov 2, 2023 · 0 comments
Open

bug post-optimization analysis #1

EliseoMolina opened this issue Nov 2, 2023 · 0 comments

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@EliseoMolina
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Hello, I am not experienced on using Matlab but I am trying to use your algorithm lgemRNA.

First I am attempting to reproduce your results runnig the algorithm with your own data. Everything works well for the non-optimization task. However, if I activate any of the task for post-optimization part the algorith tend to crash. Especifically it cannot writte the xls results. Here is an example of the error:

Error using xlwrite
Java exception occurred:
java.io.FileNotFoundException: resultsPostOptimization\contextSpecificModels\SRR8994357_WT.xls (El sistema no puede encontrar la rutaespecificada)

at java.io.FileOutputStream.open0(Native Method)

at java.io.FileOutputStream.open(FileOutputStream.java:270)

at java.io.FileOutputStream.<init>(FileOutputStream.java:213)

at java.io.FileOutputStream.<init>(FileOutputStream.java:101)

Error in model2xls (line 125)
xlwrite(fileName,tmpData,'Reaction List');

Error in writeCbModel (line 219)
model2xls(model, fileName, input.compSymbols, input.compNames);

Error in createContextSpecificModel (line 198)
writeCbModel(model, excelFileName);

Error in main (line 159)
createContextSpecificModel(inputData.modelPath,inputData.trDataPath,inputData.mediumDataPath,inputData.growthNotAffectingGeneDel, inputData.meetMinimumGrowthReq, thresholdingApproach, lowerGlobalThresholdVal, upperGlobalThresholdVal, inputData.objectiveFunction, gmAndOperation, gmOrOperation, inputData.constrAll, inputData.excludeBiomassEquation, inputData.biomassId, inputData.percentile);

Error in IgemRNA>OK (line 308)
main(data);

Error while evaluating UIControl Callback.

From that errors some questions come up:

  1. Why is it necessary to already have a directory with the xls results for post-optimization algorithm? It is not supposed to be crated for the algorithm?

  2. What will happen when I try to use the algorithm with my data, should I have to create the directory? why?

Could you please help me to fix this bug in order to use your algorithm?

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