diff --git a/responders/JAMFProtect/JAMFProtect_IOC.py b/responders/JAMFProtect/JAMFProtect_IOC.py
new file mode 100755
index 000000000..250d9ff16
--- /dev/null
+++ b/responders/JAMFProtect/JAMFProtect_IOC.py
@@ -0,0 +1,277 @@
+#!/usr/bin/env python3
+
+from cortexutils.responder import Responder
+import re
+from urllib.parse import urlparse
+import requests
+import json
+
+class JAMFProtect_IOC(Responder):
+    def __init__(self):
+        Responder.__init__(self)
+        self.base_url = self.get_param("config.base_url")
+        self.client_id = self.get_param("config.client_id")
+        self.password = self.get_param("config.password")
+        self.service = self.get_param("config.service", None)
+    
+    def identify_and_extract(self, input_string):
+        # regular expressions for different types
+        patterns = {
+            "sha256": re.compile(r"^[a-fA-F0-9]{64}$"),
+            "md5": re.compile(r"^[a-fA-F0-9]{32}$"),
+            "sha1": re.compile(r"^[a-fA-F0-9]{40}$"),
+            "ipv4": re.compile(r"^(\d{1,3}\.){3}\d{1,3}$"),
+            "ipv6": re.compile(r"^([0-9a-fA-F]{1,4}:){7}([0-9a-fA-F]{1,4}|:)|(([0-9a-fA-F]{1,4}:){1,7}|:)(:([0-9a-fA-F]{1,4}|:)){1,7}$"),
+            "domain": re.compile(r"^(?!:\/\/)([a-zA-Z0-9-_]+\.)*([a-zA-Z0-9-_]{2,})(\.[a-zA-Z]{2,11})$")
+        }
+
+        # check if the input_string matches any of the patterns
+        for key, pattern in patterns.items():
+            if pattern.match(input_string):
+                return key, input_string
+
+        # check if the input_string is a URL and extract the domain
+        try:
+            parsed_url = urlparse(input_string)
+            if parsed_url.scheme and parsed_url.netloc:
+                domain = parsed_url.netloc
+                # handle URLs with "www."
+                if domain.startswith("www."):
+                    domain = domain[4:]
+                return "domain", domain
+        except Exception as e:
+            self.error(f"Error parsing URL: {e}")
+
+        return None
+
+    def get_jamf_token(self, base_url: str, client_id: str, password: str) -> str:
+        """
+        Function to obtain a token from the Jamf Protect API.
+
+        Parameters:
+        - base_url (str): The base URL of your Jamf Protect instance (e.g., "https://mycompany.protect.jamfcloud.com").
+        - client_id (str): The client ID for authentication.
+        - password (str): The password for authentication.
+
+        Returns:
+        - str: The access token if successful, raises an exception if it fails.
+        """
+        token_url = f"{base_url}/token"
+        headers = {'content-type': 'application/json'}
+        data = {
+            "client_id": client_id,
+            "password": password
+        }
+
+        try:
+            response = requests.post(token_url, headers=headers, data=json.dumps(data))
+            response.raise_for_status()
+            access_token = response.json().get('access_token')
+            if access_token:
+                return access_token
+            else:
+                raise ValueError("Failed to retrieve access token.")
+        except requests.exceptions.RequestException as e:
+            raise RuntimeError(f"Failed to obtain token: {e}")
+
+    def add_hash_to_prevention_list(self, base_url: str, token: str, list_name: str, description: str, hash_value: str, tags: list):
+        """
+        Function to add a hash to a custom prevention list in Jamf Protect using GraphQL.
+        """
+        graphql_url = f"{base_url}/graphql"
+        headers = {
+            "Authorization": f"{token}",
+            "Content-Type": "application/json"
+        }
+
+        # Construct the GraphQL mutation payload
+        payload = {
+            "operationName": "createPreventList",
+            "variables": {
+                "name": list_name,
+                "description": description,
+                "type": "FILEHASH",
+                "list": [hash_value],
+                "tags": tags
+            },
+            "query": """
+            mutation createPreventList($name: String!, $tags: [String]!, $type: PREVENT_LIST_TYPE!, $list: [String]!, $description: String) {
+                createPreventList(
+                    input: {name: $name, tags: $tags, type: $type, list: $list, description: $description}
+                ) {
+                    ...PreventListFields
+                    __typename
+                }
+            }
+            
+            fragment PreventListFields on PreventList {
+                id
+                name
+                type
+                count
+                list
+                created
+                description
+                __typename
+            }
+            """
+        }
+        # Make the GraphQL request
+        response = requests.post(graphql_url, headers=headers, json=payload)
+        response.raise_for_status()
+
+        result = response.json()
+        if 'errors' in result:
+            return f"Failed to add hash to prevention list: {result['errors']}"
+        else:
+            return f"Hash {hash_value} successfully added to prevention list {list_name}."
+
+    def get_prevention_list_id(self, base_url: str, token: str, list_name: str) -> str:
+        """
+        Function to get the ID of a prevention list by its name.
+        """
+        graphql_url = f"{base_url}/graphql"
+        headers = {
+            "Authorization": f"{token}",
+            "Content-Type": "application/json"
+        }
+
+        payload = {
+            "operationName": "listPreventLists",
+            "variables": {
+                "nextToken": None,
+                "direction": "ASC",
+                "field": "created",
+                "filter": None
+            },
+            "query": """
+            query listPreventLists($nextToken: String, $direction: OrderDirection!, $field: PreventListOrderField!, $filter: PreventListFilterInput) {
+                listPreventLists(
+                    input: {next: $nextToken, order: {direction: $direction, field: $field}, pageSize: 100, filter: $filter}
+                ) {
+                    items {
+                        ...PreventListFields
+                        __typename
+                    }
+                    pageInfo {
+                        next
+                        total
+                        __typename
+                    }
+                    __typename
+                }
+            }
+
+            fragment PreventListFields on PreventList {
+                id
+                name
+                type
+                count
+                list
+                created
+                description
+                __typename
+            }
+            """
+        }
+
+
+        response = requests.post(graphql_url, headers=headers, json=payload)
+        response.raise_for_status()
+
+        # check if the response contains valid json data
+        try:
+            result = response.json()
+        except ValueError as e:
+            raise RuntimeError(f"Failed to decode JSON response: {e}")
+
+        prevention_lists = result['data']['listPreventLists']['items']
+
+        prevention_lists_ids = []
+        # Search for the list with the specified name
+        for prevention_list in prevention_lists:
+            if prevention_list['name'] == list_name:
+                prevention_lists_ids.append(prevention_list['id'])
+        
+        if prevention_lists_ids == []:
+            raise ValueError(f"No prevention list found with name: {list_name}")
+        
+        return prevention_lists_ids
+
+
+
+    def delete_prevention_list(self, base_url: str, token: str, prevent_list_ids: list):
+        """
+        Function to delete a prevention list in Jamf Protect using GraphQL.
+        """
+        graphql_url = f"{base_url}/graphql"
+        headers = {
+            "Authorization": f"{token}",
+            "Content-Type": "application/json"
+        }
+
+        failed_deletions = []
+        
+        for prevent_list_id in prevent_list_ids:
+            # Construct the GraphQL mutation payload
+            payload = {
+                "operationName": "deletePreventList",
+                "variables": {
+                    "id": prevent_list_id
+                },
+                "query": """
+                mutation deletePreventList($id: ID!) {
+                    deletePreventList(id: $id) {
+                        id
+                        __typename
+                    }
+                }
+                """
+            }
+
+            # Make the GraphQL request
+            response = requests.post(graphql_url, headers=headers, json=payload)
+            response.raise_for_status()
+
+            result = response.json()
+            if 'errors' in result:
+                failed_deletions.append(prevent_list_id)
+
+        if failed_deletions:
+            return f"Failed to delete prevention list(s): {', '.join(failed_deletions)}"
+        
+        return f"Prevention list with ID(s) {', '.join(prevent_list_ids)} successfully deleted."
+
+    
+    def run(self):
+        result = ""
+        observable_value = self.get_param("data.data", None)
+        ioc_type, ioc_value = self.identify_and_extract(observable_value)
+        if ioc_type not in ["sha256", "sha1"]:
+            self.error("error -- Not a hash or a valid hash : sha1 or sha256")
+
+        case_title = self.get_param("data.case.title", None, "Can't get case title")
+        case_id = self.get_param("data.case.id", None, "Can't get case ID")
+        description = f"Pushed from TheHive - {case_title} - {case_id}"
+
+        if self.service == "addIOC":
+
+            token = self.get_jamf_token(self.base_url, self.client_id, self.password)
+
+            result = self.add_hash_to_prevention_list(self.base_url,token, description, description, ioc_value, ["TheHive", f"{case_id}"])      
+        elif self.service == "removeIOC":
+            token = self.get_jamf_token(self.base_url, self.client_id, self.password)
+
+            prevention_list_ids = self.get_prevention_list_id(self.base_url, token, description)
+            result = self.delete_prevention_list(self.base_url, token, prevention_list_ids)
+        
+        if 'error' in result:
+           self.error(result)
+        
+        self.report({"message": result})
+            
+
+
+
+if __name__ == '__main__':
+    JAMFProtect_IOC().run()
\ No newline at end of file
diff --git a/responders/JAMFProtect/JAMFProtect_addHashtoPreventList.json b/responders/JAMFProtect/JAMFProtect_addHashtoPreventList.json
new file mode 100644
index 000000000..162521b72
--- /dev/null
+++ b/responders/JAMFProtect/JAMFProtect_addHashtoPreventList.json
@@ -0,0 +1,50 @@
+{
+  "name": "JAMFProtect_addHashtoPreventList",
+  "version": "1.0",
+  "author": "nusantara-self, StrangeBee",
+  "url": "https://github.com/TheHive-Project/Cortex-Analyzers",
+  "license": "AGPL-V3",
+  "description": "Add IOC to JAMF Protect - creates a custom prevent list for a hash",
+  "dataTypeList": [
+    "thehive:case_artifact"
+  ],
+  "command": "JAMFProtect/JAMFProtect_IOC.py",
+  "baseConfig": "JAMFProtect",
+  "config": {
+    "service": "addIOC"
+  },
+  "configurationItems": [
+    {
+      "name": "base_url",
+      "description": "JAMF Protect base url",
+      "type": "string",
+      "multi": false,
+      "required": true,
+      "defaultValue": "https://mycompany.protect.jamfcloud.com"
+    },
+    {
+      "name": "client_id",
+      "description": "JAMF Protect client ID",
+      "type": "string",
+      "multi": false,
+      "required": true,
+      "defaultValue": ""
+    },
+    {
+      "name": "password",
+      "description": "JAMF Protect password",
+      "type": "string",
+      "multi": false,
+      "required": true,
+      "defaultValue": ""
+    }
+  ],
+  "registration_required": true,
+  "subscription_required": true,
+  "free_subscription": false,
+  "service_homepage": "https://www.jamf.com/products/jamf-protect/",
+  "service_logo": {
+    "path": "assets/jamfprotect.png",
+    "caption": "JAMF Protect logo"
+  }
+}
diff --git a/responders/JAMFProtect/JAMFProtect_removeHashfromPreventList.json b/responders/JAMFProtect/JAMFProtect_removeHashfromPreventList.json
new file mode 100644
index 000000000..d152136c0
--- /dev/null
+++ b/responders/JAMFProtect/JAMFProtect_removeHashfromPreventList.json
@@ -0,0 +1,50 @@
+{
+  "name": "JAMFProtect_removeHashfromPreventList",
+  "version": "1.0",
+  "author": "nusantara-self, StrangeBee",
+  "url": "https://github.com/TheHive-Project/Cortex-Analyzers",
+  "license": "AGPL-V3",
+  "description": "Remove IOC on JAMF Protect - removes associated custom prevent list(s) containing the hash",
+  "dataTypeList": [
+    "thehive:case_artifact"
+  ],
+  "command": "JAMFProtect/JAMFProtect_IOC.py",
+  "baseConfig": "JAMFProtect",
+  "config": {
+    "service": "removeIOC"
+  },
+  "configurationItems": [
+    {
+      "name": "base_url",
+      "description": "JAMF Protect base url",
+      "type": "string",
+      "multi": false,
+      "required": true,
+      "defaultValue": "https://mycompany.protect.jamfcloud.com"
+    },
+    {
+      "name": "client_id",
+      "description": "JAMF Protect client ID",
+      "type": "string",
+      "multi": false,
+      "required": true,
+      "defaultValue": ""
+    },
+    {
+      "name": "password",
+      "description": "JAMF Protect password",
+      "type": "string",
+      "multi": false,
+      "required": true,
+      "defaultValue": ""
+    }
+  ],
+  "registration_required": true,
+  "subscription_required": true,
+  "free_subscription": false,
+  "service_homepage": "https://www.jamf.com/products/jamf-protect/",
+  "service_logo": {
+    "path": "assets/jamfprotect.png",
+    "caption": "JAMF Protect logo"
+  }
+}
diff --git a/responders/JAMFProtect/README.md b/responders/JAMFProtect/README.md
new file mode 100644
index 000000000..e61dc54d6
--- /dev/null
+++ b/responders/JAMFProtect/README.md
@@ -0,0 +1,10 @@
+### JAMF Protect Prevent List
+
+This responder manages [JAMF Protect prevent lists](https://docs.jamf.com/jamf-protect/administrator-guide/Prevent_Lists.html) by adding or removing hashes as needed.
+
+#### Setup
+- Navigate to **Administrative** > **Account**
+- Create a role **PreventList-Write** with permissions **Prevent Lists: Read & Write**
+- Create an API client and assign the above role
+- Use these API credentials in your responders
+
diff --git a/responders/JAMFProtect/assets/jamfprotect.png b/responders/JAMFProtect/assets/jamfprotect.png
new file mode 100644
index 000000000..b3e566f23
Binary files /dev/null and b/responders/JAMFProtect/assets/jamfprotect.png differ
diff --git a/responders/JAMFProtect/requirements.txt b/responders/JAMFProtect/requirements.txt
new file mode 100644
index 000000000..4a21dbf63
--- /dev/null
+++ b/responders/JAMFProtect/requirements.txt
@@ -0,0 +1,2 @@
+cortexutils
+requests
\ No newline at end of file