diff --git a/CHANGELOG.md b/CHANGELOG.md
index b91514186..ab656789a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -6,6 +6,10 @@
 -   Optimized icon caching to reduce file size in generated HTML documentation, #2287.
 -   Added `MarkdownEvent.INCLUDE` for plugins, #2284.
 
+### Bug Fixes
+
+-   Comments are no longer removed from classes/interfaces containing call signatures, #2290.
+
 ### Thanks!
 
 -   @krisztianb
diff --git a/src/lib/converter/plugins/CommentPlugin.ts b/src/lib/converter/plugins/CommentPlugin.ts
index 42e167aa9..ae4e3e295 100644
--- a/src/lib/converter/plugins/CommentPlugin.ts
+++ b/src/lib/converter/plugins/CommentPlugin.ts
@@ -376,12 +376,16 @@ export class CommentPlugin extends ConverterComponent {
             return;
         }
 
-        const comment = reflection.comment;
+        const comment = reflection.kindOf(ReflectionKind.ClassOrInterface)
+            ? undefined
+            : reflection.comment;
 
         // Since this reflection has signatures, remove the comment from the parent
         // reflection. This is important so that in type aliases we don't end up with
         // a comment rendered twice.
-        delete reflection.comment;
+        if (!reflection.kindOf(ReflectionKind.ClassOrInterface)) {
+            delete reflection.comment;
+        }
 
         for (const signature of signatures) {
             const childComment = (signature.comment ||= comment?.clone());
diff --git a/src/test/converter/interface/specs.json b/src/test/converter/interface/specs.json
index 801ed129f..df317345b 100644
--- a/src/test/converter/interface/specs.json
+++ b/src/test/converter/interface/specs.json
@@ -1870,6 +1870,14 @@
               "variant": "declaration",
               "kind": 256,
               "flags": {},
+              "comment": {
+                "summary": [
+                  {
+                    "kind": "text",
+                    "text": "Function signature of an event listener callback"
+                  }
+                ]
+              },
               "sources": [
                 {
                   "fileName": "interface-implementation.ts",
diff --git a/src/test/converter2/issues/gh2290.ts b/src/test/converter2/issues/gh2290.ts
new file mode 100644
index 000000000..f0d7906b5
--- /dev/null
+++ b/src/test/converter2/issues/gh2290.ts
@@ -0,0 +1,14 @@
+/** Int comment */
+export interface CallSignature {
+    /** Sig comment */
+    (x: string): void;
+}
+
+/** Int comment */
+export interface CallSignature2 {
+    /** Sig comment */
+    (x: string): void;
+
+    /** Prop comment */
+    prop: 123;
+}
diff --git a/src/test/issues.c2.test.ts b/src/test/issues.c2.test.ts
index c0d851fa8..e531ddd10 100644
--- a/src/test/issues.c2.test.ts
+++ b/src/test/issues.c2.test.ts
@@ -27,7 +27,7 @@ import { TestLogger } from "./TestLogger";
 import { clearCommentCache } from "../lib/converter/comments";
 import { join } from "path";
 import { existsSync } from "fs";
-import { getLinks, query } from "./utils";
+import { getComment, getLinks, query } from "./utils";
 
 const base = getConverter2Base();
 const app = getConverter2App();
@@ -1111,4 +1111,26 @@ describe("Issue Tests", () => {
             },
         ]);
     });
+
+    it("Handles comments on interfaces with call signatures #2290", () => {
+        const project = convert();
+
+        equal(getComment(project, "CallSignature"), "Int comment");
+        equal(getComment(project, "CallSignature2"), "Int comment");
+        equal(getComment(project, "CallSignature2.prop"), "Prop comment");
+
+        equal(
+            Comment.combineDisplayParts(
+                query(project, "CallSignature").signatures![0].comment?.summary
+            ),
+            "Sig comment"
+        );
+
+        equal(
+            Comment.combineDisplayParts(
+                query(project, "CallSignature2").signatures![0].comment?.summary
+            ),
+            "Sig comment"
+        );
+    });
 });
diff --git a/src/test/utils.ts b/src/test/utils.ts
index 9f87dfcad..756dd3eae 100644
--- a/src/test/utils.ts
+++ b/src/test/utils.ts
@@ -1,5 +1,6 @@
 import { ok } from "assert";
 import {
+    Comment,
     DeclarationReflection,
     ProjectReflection,
     Reflection,
@@ -13,6 +14,10 @@ export function query(project: ProjectReflection, name: string) {
     return reflection;
 }
 
+export function getComment(project: ProjectReflection, name: string) {
+    return Comment.combineDisplayParts(query(project, name).comment?.summary);
+}
+
 export function getLinks(refl: Reflection): Array<{
     display: string;
     target: undefined | string | [ReflectionKind, string];