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[Stretch] Implement modifications to getSubnetworkFromIndra #16

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tonywu1999 opened this issue Sep 12, 2024 · 0 comments
Open

[Stretch] Implement modifications to getSubnetworkFromIndra #16

tonywu1999 opened this issue Sep 12, 2024 · 0 comments

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@tonywu1999
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Context

MSstatsBioNet consists of a function called getSubnetworkFromIndra that fetches a subnetwork from INDRA. This is particularly useful for protein discovery applications. This task involves some minor tweaks to this function.

Subtasks

  • Add a logFC and p-value cutoff parameters to filter on the proteins
  • Add exception handling when INDRA returns an error
    • Particularly when INDRA returns an error related to a 400 node limit to its API, MSstatsBioNet should notify users of this limit and to consider adjusting p-value/logFC cutoffs.
  • Add unit tests
  • PR and merge

Acceptance Criteria

We should be able to produce a subnetwork with proper filtering using this CCRCC dataset. If an error occurs, it's clear what action is required of users.

@tonywu1999 tonywu1999 changed the title [Pruthvi] Implement modifications to getSubnetworkFromIndra [Stretch] Implement modifications to getSubnetworkFromIndra Nov 13, 2024
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