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Reconstruction likelihood #30

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ttgump opened this issue Mar 13, 2024 · 0 comments
Open

Reconstruction likelihood #30

ttgump opened this issue Mar 13, 2024 · 0 comments

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@ttgump
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ttgump commented Mar 13, 2024

Hi,
In other scVI models, it uses negative binomial (NB) or zero-inflated negative binomial (ZINB) to characterize discrete count of mRNA data directly. So I just want to know why you choose normal distribution to model unspliced and spliced mRNA counts in veloVI model but not NB or ZINB?
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