diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index ec6546f4d4..28016f16d3 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -37,6 +37,8 @@ v33.0.0 (next next, roadmap)
   of these in other summary plugins.
   See https://github.com/nexB/scancode-toolkit/issues/1745
 
+- Update intbitset and related dependencies for Python 3.13.0 support.
+
 v32.3.0 - 2024-10-21
 --------------------
 
diff --git a/requirements-native.txt b/requirements-native.txt
index f1f2b09b80..672f0b1bd7 100644
--- a/requirements-native.txt
+++ b/requirements-native.txt
@@ -1,6 +1,6 @@
-cffi==1.16.0
+cffi==1.17.1
 intbitset==3.1.0
-lxml==5.1.0
+lxml==5.3.0
 MarkupSafe==2.1.5
 pyahocorasick==2.1.0
 PyYAML==6.0.1
diff --git a/requirements.txt b/requirements.txt
index e32ea2d6a4..f1c183ab45 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -5,7 +5,7 @@ binaryornot==0.4.4
 beartype==0.17.2
 boolean.py==4.0
 certifi==2024.2.2
-cffi==1.16.0
+cffi==1.17.1
 chardet==5.0.0
 charset-normalizer==2.1.0
 click==8.1.7
@@ -36,7 +36,7 @@ javaproperties==0.8.1
 Jinja2==3.1.3
 jsonstreams==0.6.0
 license-expression==30.3.0
-lxml==5.1.0
+lxml==5.3.0
 MarkupSafe==2.1.5
 more-itertools==8.13.0
 normality==2.3.3
diff --git a/setup.cfg b/setup.cfg
index af17fdd362..9ac458f144 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -21,6 +21,7 @@ classifiers =
     Programming Language :: Python :: 3.10
     Programming Language :: Python :: 3.11
     Programming Language :: Python :: 3.12
+    Programming Language :: Python :: 3.13
     Topic :: Software Development
     Topic :: Utilities
 
@@ -85,7 +86,7 @@ install_requires =
     jinja2 >= 2.7.0
     jsonstreams >= 0.5.0
     license_expression >= 30.1.1
-    lxml >= 4.9.2
+    lxml >= 5.3.0
     MarkupSafe >= 2.1.2
     packageurl_python >= 0.9.0
     packvers >= 21.0.0