Skip to content
New issue

Have a question about this project? # for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “#”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? # to your account

Arbor-compatible NMODL representation of AMPA, NMDA, and GABA synapses #1764

Open
noraabiakar opened this issue Nov 16, 2021 · 10 comments
Open

Comments

@noraabiakar
Copy link
Contributor

Several variants of the synapses can be found here: https://github.com/dbbs-lab/dbbs-mod-collection/tree/master/dbbs_mod_collection/mod

  • AMPA_0
  • AMPA_granule
  • GABA_0
  • GABA_biexp
  • GABA_granule
  • NMDA_granule
  • NMDA_stellate.

These mechanisms employ the use of arrays and net_send. Both of these features are not supported by arbor or the modcc compiler.
This is mostly a placeholder issue.

@schmitts
Copy link
Contributor

Do we have users requesting these mechanisms?

@noraabiakar
Copy link
Contributor Author

The arborio team has been requesting these mechanism. I will tag the issue.

@noraabiakar
Copy link
Contributor Author

Meetings of minutes related to this top can be found here

@noraabiakar noraabiakar added this to the v0.7 milestone Feb 16, 2022
@brenthuisman
Copy link
Contributor

@boeschf will try to get hold of @noraabiakar to see what the status is, and where the code is, if any.

@thorstenhater
Copy link
Contributor

thorstenhater commented May 10, 2022

Code is here: https://github.com/noraabiakar/synapses
but we have no PR or assignee, yet.

@brenthuisman
Copy link
Contributor

@noraabiakar would you still be interested in wrapping this up? A minimal PR would be OK!

@brenthuisman brenthuisman modified the milestones: v0.7, v0.8 Aug 2, 2022
@brenthuisman
Copy link
Contributor

@Helveg Do you still need this? Are there other AMPA/NMDA/GABA nmodl that do work, e.g. from a modeldb or do you need these specific ones? If so, why? We can discuss offline.

@brenthuisman brenthuisman modified the milestones: v0.8, v0.9 Aug 30, 2022
@Helveg
Copy link
Collaborator

Helveg commented Aug 30, 2022

Yes, still a project requirement of arborio

@brenthuisman
Copy link
Contributor

Is the requirement for these specific ones, or could other implementations of these mechs be used? At the dev meet, it was suggested there exist mechs doing e.g. AMPA that don't rely on currently unsupported NMODL. Is that an option?

@thorstenhater
Copy link
Contributor

# for free to join this conversation on GitHub. Already have an account? # to comment
Projects
None yet
Development

No branches or pull requests

5 participants