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There are bugs in version 1.6 #764

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ColinR01 opened this issue Jan 19, 2024 · 4 comments
Closed

There are bugs in version 1.6 #764

ColinR01 opened this issue Jan 19, 2024 · 4 comments
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@ColinR01
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Have you checked the FAQ? https://github.com/google/deepvariant/blob/r1.6/docs/FAQ.md:

Describe the issue:
When variant is not detected, the program will freeze in the last step;

Setup

  • Operating system:Centos7.6
  • DeepVariant version: 1.6
  • Installation method (Docker, built from source, etc.): singularity
  • Type of data: (sequencing instrument, reference genome, anything special that is unlike the case studies?) PACBIO-SMART;A reference sequence for a normal person;

Steps to reproduce:

  • Command: /bin/singularity run -B /work/:/work/ /work/deepvariant.sif /opt/deepvariant/bin/run_deepvariant --model_type=PACBIO --ref=human_geneA_reference.fa --reads=reference.align.bam --output_vcf=out.vcf --output_gvcf=out.gvcf --num_shards=32
  • Error trace: Last line: I0119 11:43:53.450599 47012502976320 call_variants.py:623] Complete: call_variants(Stuck at this step).

Does the quick start test work on your system?
Please test with https://github.com/google/deepvariant/blob/r1.6/docs/deepvariant-quick-start.md.
Is there any way to reproduce the issue by using the quick start?

Any additional context:

deepvariant_1.6.pdf

@kishwarshafin
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@ColinR01 ,

Is it possible to provide the input files to reproduce this result?

@pichuan
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pichuan commented Jan 30, 2024

I believe @kishwarshafin was able to reproduce the issue and is currently looking into a fix.
Keeping this open for now.

@kishwarshafin
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Hi @ColinR01 ,

Please try the following docker that has the patch incorporated that should fix your issue:

docker pull google/deepvariant:CL602468145
docker pull google/deepvariant:CL602468145-gpu

@kishwarshafin
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@ColinR01 , Can you please try the v1.6.1 docker? If the issue isn't resolved, please feel free to reopen this bug.

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