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DESCRIPTION
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Type: Package
Package: simIDM
Title: Simulating Oncology Trials using an Illness-Death Model
Version: 0.1.0.9006
Authors@R: c(
person("Alexandra", "Erdmann", , "alexandra.erdmann@uni-ulm.de", role = c("aut", "cre")),
person("Kaspar", "Rufibach", , "kaspar.rufibach@roche.com", role = "aut"),
person("Holger", "Löwe", , "hbj.loewe@gmail.com", role = "aut"),
person("Daniel", "Sabanés Bové", , "daniel.sabanes_bove@roche.com", role = "aut"),
person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")),
person("University of Ulm", role = c("cph", "fnd"))
)
Description: Based on the illness-death model a large number of clinical
trials with oncology endpoints progression-free survival (PFS) and
overall survival (OS) can be simulated, see Meller, Beyersmann and
Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows
for random and event-driven censoring, an arbitrary number of
treatment arms, staggered study entry and drop-out. Exponentially,
Weibull and piecewise exponentially distributed survival times can be
generated. The correlation between PFS and OS can be calculated.
License: Apache License 2.0
URL: https://github.com/insightsengineering/simIDM/
BugReports: https://github.com/insightsengineering/simIDM/issues
Depends:
R (>= 3.6)
Imports:
checkmate,
furrr,
future,
mstate,
parallelly,
stats,
survival
Suggests:
coxphw,
knitr,
mvna,
prodlim,
rmarkdown,
rpact,
testthat (>= 3.0.0)
VignetteBuilder:
knitr
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-US
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2