Genomic Grammar Data Processing.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Signals Analysis Data Processing"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "### header ###\n",
    "__author__ = \"Jenhan Tao\"\n",
    "__license__ = \"BSD\"\n",
    "__email__ = \"jenhantao@gmail.com\"\n",
    "%load_ext autoreload\n",
    "%autoreload 2\n",
    "### imports ###\n",
    "import sys\n",
    "%matplotlib inline\n",
    "import os\n",
    "import pandas as pd\n",
    "import numpy as np\n",
    "import matplotlib\n",
    "import threading\n",
    "import matplotlib.pyplot as plt \n",
    "import seaborn as sns\n",
    "from collections import Counter\n",
    "matplotlib.pylab.rcParams['savefig.dpi'] = 200\n",
    "sys.setrecursionlimit(3000)\n",
    "import pickle\n",
    "from sklearn import preprocessing\n",
    "import time\n",
    "sns.set_context('talk')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Preprocessing"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "workingDirectory = '/home/jtao/analysis/genomic_grammar_analysis/'\n",
    "os.chdir(workingDirectory)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 86,
   "metadata": {},
   "outputs": [],
   "source": [
    "%%capture\n",
    "!summarize_logs.py atac ./qc_atac ./tag_directories_atac/*/"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [],
   "source": [
    "summary_atac_frame = pd.read_csv('./qc_atac/mapping_stats.tsv', sep='\\t')\n",
    "summary_atac_frame['genome'] = 'mm10'\n",
    "sample_names = summary_atac_frame['sample'].values\n",
    "summary_atac_frame['strain'] = [x.split('_')[0] for x in sample_names]\n",
    "summary_atac_frame['date'] = [x.split('_')[5] for x in sample_names]\n",
    "summary_atac_frame['treatment'] = [x.split('_')[3] for x in sample_names]\n",
    "\n"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## C57Bl6 ATAC-seq"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Mapping Quality Control"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 88,
   "metadata": {
    "scrolled": false
   },
   "outputs": [
    {
     "data": {
      "image/png": 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GjB4HlbjMriTvqQ6c3qucJC6c099JdmCvLyIzq2ojBZGXQ2rYeuDUDqtQx7xj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\nJKFb33I/n2+z7A+x9cycwEWuv/xeVSeEN3Lz3Xc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epLL5/I46e2NUzy4h3cFu3qSy/fN5MQ+p3z3JO61npZ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\n",
      "text/plain": [
       "<matplotlib.figure.Figure at 0x7ff27a98ab00>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "image/png": 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x3uMaNqX3PtcvgD2MGeD+c1wjf6PMD/1AVr9GPpCZg577HeCwEVKL1yMx67ru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\nxJzpDyPippRzt1n3npiZ35x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      "text/plain": [
       "<matplotlib.figure.Figure at 0x7ff2716e72e8>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "image/png": 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47wAROUdVn+pAnc7GFIAzhGtvJiJz5oUrDYihBuP7+mMH6lSF8zCBUNzQ7kBi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\n7n3AViLytfaqNKI5k2zowOWA/ZudFIx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vczJd1Ve8jXWNnyam7awO2UC8rTq9eWwD9PslKSxici3gC8iakH5/MoN5k2p1w4Qrlo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\nWp4nUQJLnTLawLeA/QbJODNPpwRCfsbU7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      "text/plain": [
       "<matplotlib.figure.Figure at 0x7ff28bd5f390>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "text/plain": [
       "<matplotlib.text.Text at 0x7ff27d0f7278>"
      ]
     },
     "execution_count": 88,
     "metadata": {},
     "output_type": "execute_result"
    },
    {
     "data": {
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lhtK/x5OUpg39Xozx0QaVKkmSJEmSJEmSpDmgEWsGjkrV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\nIcnRJH89ycCbDjud5J8n+XOllK8ppRwopfzfpZSHkrwryU8kOZuL4dh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      "text/plain": [
       "<matplotlib.figure.Figure at 0x7ff27874a320>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# plot distribution of uniquely mapped reads\n",
    "sns.distplot(summary_atac_frame['uniquelyMappedFraction'], bins=20, kde=False)\n",
    "plt.title('Distribution of Fraction of Uniquely Mapped Reads per Sample (Pre-filtering)')\n",
    "plt.xlabel('Uniquely Mapped Reads Fraction')\n",
    "plt.ylabel('Frequency')\n",
    "plt.show()\n",
    "\n",
    "sns.distplot(summary_atac_frame['clonality'].values, bins=20, kde=False)\n",
    "plt.title('Distribution of Tags Per Position (Pre-filtering)')\n",
    "plt.xlabel('Tags Per Position')\n",
    "plt.ylabel('Frequency')\n",
    "plt.show()\n",
    "\n",
    "\n",
    "# Distribution of Uniquely Mapped Reads per Sample\n",
    "sns.distplot(summary_atac_frame['uniquelyMappedReads'], bins=20, kde=False, color=sns.xkcd_rgb[\"royal blue\"])\n",
    "plt.title('Distribution of Uniquely Mapped Reads per Sample (Pre-filtering)')\n",
    "plt.show()\n",
    "\n",
    "\n",
    "plt.scatter(x = summary_atac_frame['totalReads'].astype(float).values, y=summary_atac_frame['uniquelyMappedReads'].astype(float).values)\n",
    "plt.xlabel('Total Reads')\n",
    "plt.ylabel('Uniquely Mapped Reads')\n",
    "# sns.distplot(summary_frame['spot'], kde=False, bins =50)\n",
    "# plt.show()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Filter Samples According to Mapping Quality"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 90,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Number of Samples: 27\n",
      "Number of discarded samples: 0\n",
      "Number of Samples remaining after filtering: 27\n"
     ]
    }
   ],
   "source": [
    "# filter samples according to threshold for the fraction of uniquely mapped reads\n",
    "mappedFractionThreshold = -1\n",
    "uniquelyMappedReadThreshold = -1\n",
    "\n",
    "filtered_summary_atac_frame = summary_atac_frame.copy()\n",
    "# # filter on fraction of mapped reads\n",
    "# filtered_summary_atac_frame = filtered_summary_atac_frame[filtered_summary_atac_frame['mappedFraction'] >= mappedFractionThreshold]\n",
    "# # filter on total mapped reads\n",
    "# filtered_summary_atac_frame = filtered_summary_atac_frame[filtered_summary_atac_frame['uniquelyMappedReads'] >= uniquelyMappedReadThreshold]\n",
    "\n",
    "# get samples that were discarded\n",
    "discardedSampleNames = [x for x in summary_atac_frame['sample'].values if not x in filtered_summary_atac_frame['sample'].values]\n",
    "discarded_summary_atac_frame = summary_atac_frame[summary_atac_frame['sample'].isin(discardedSampleNames)]\n",
    "print(\"Number of Samples:\", summary_atac_frame.shape[0])\n",
    "print(\"Number of discarded samples:\",discarded_summary_atac_frame.shape[0])\n",
    "print(\"Number of Samples remaining after filtering:\", filtered_summary_atac_frame.shape[0])\n",
    "\n",
    "# generate simplified name for naming output files\n",
    "factorTreatment_count_dict = {} #{factor-treatment:count}\n",
    "simplifiedNames = []\n",
    "for simpleNameRoot in list((filtered_summary_atac_frame['strain'] \n",
    "                            + '_' + filtered_summary_atac_frame['treatment'] \n",
    "                            + '_' + filtered_summary_atac_frame['date']).values):\n",
    "    if not simpleNameRoot in factorTreatment_count_dict:\n",
    "        factorTreatment_count_dict[simpleNameRoot] = 1\n",
    "    else:\n",
    "        factorTreatment_count_dict[simpleNameRoot] += 1\n",
    "    simplifiedName = (simpleNameRoot + '_' + str(factorTreatment_count_dict[simpleNameRoot])).lower()\n",
    "    simplifiedNames.append(simplifiedName)\n",
    "\n",
    "filtered_summary_atac_frame[\"simplifiedName\"] = simplifiedNames\n",
    "\n",
    "originalName_simpleName_dict = dict(zip(filtered_summary_atac_frame['sample'].values,\n",
    "                                       filtered_summary_atac_frame['simplifiedName'].values))\n",
    "simpleName_originalName_dict = dict(zip(filtered_summary_atac_frame['simplifiedName'].values,\n",
    "                                       filtered_summary_atac_frame['sample'].values))\n",
    "\n"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Peak Calling"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 91,
   "metadata": {},
   "outputs": [],
   "source": [
    "# %%capture \n",
    "# suppress output - this can be saved to a variable (like a log file)\n",
    "\n",
    "### call peaks ###\n",
    "# iterate through each individual file\n",
    "peakDirectory = workingDirectory + '/' + 'atac_peak_files'\n",
    "\n",
    "if not os.path.exists(peakDirectory):\n",
    "    os.makedirs(peakDirectory)\n",
    "\n",
    "# make peak files with simplified names\n",
    "# filteredSamples = list(filtered_mappingStats_frame['sampleName'].values)\n",
    "scriptFile1 = open('./peakCalling_homer_idr.sh', 'w')\n",
    "scriptFile2 = open('./peakCalling_homer.sh', 'w')\n",
    "\n",
    "atacTagDirPath = './tag_directories_atac/'\n",
    "for tagDir in filtered_summary_atac_frame['sample'].values:\n",
    "    # call peaks only for experiments that passed thresholding\n",
    "    metaDataTokens = tagDir.split(\"_\")\n",
    "    treatment = metaDataTokens[4]\n",
    "\n",
    "    peakFileName1 = originalName_simpleName_dict[tagDir] + \"_peaks.tsv\"\n",
    "    peakFileName2 = originalName_simpleName_dict[tagDir] + \"_default_peaks.tsv\"\n",
    "\n",
    "    scriptFile1.write('findPeaks ' + atacTagDirPath + '/' + tagDir \n",
    "                     + ' -L 0 -C 0 -fdr 0.9' \n",
    "                     + ' -style factor -size 200  > ' + \n",
    "                     peakDirectory + '/' + peakFileName1 + ' &\\n')\n",
    "    scriptFile2.write('findPeaks ' + atacTagDirPath + '/' + tagDir\n",
    "                 + ' -style factor -size 200 > ' + \n",
    "                 peakDirectory +'/' + peakFileName2 + ' &\\n')\n",
    "scriptFile1.close()\n",
    "scriptFile2.close()\n",
    "\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "\tFragment Length = 77\n",
      "\tTotal Tags = 23688056.0\n",
      "\tTags per bp = 0.011844\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 73\n",
      "\tFragment Length = 77\n",
      "\tTotal Tags = 15990733.0\n",
      "\tTags per bp = 0.007995\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tTotal Tags = 16739327.0\n",
      "\tTags per bp = 0.008370\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 77\n",
      "\tTotal Tags = 21056721.0\n",
      "\tTags per bp = 0.010528\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 67\n",
      "\tTotal Tags = 7825213.0\n",
      "\tTags per bp = 0.003913\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 71\n",
      "\tTotal Tags = 46329172.0\n",
      "\tTags per bp = 0.023165\n",
      "\tMax tags per bp set automatically to 2.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 78\n",
      "\tTotal Tags = 23549529.0\n",
      "\tTags per bp = 0.011775\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 76\n",
      "\tTotal Tags = 7718694.0\n",
      "\tTags per bp = 0.003859\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 237\n",
      "\tTotal Tags = 5063449.0\n",
      "\tTags per bp = 0.002532\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 67\n",
      "\tTotal Tags = 7912771.0\n",
      "\tTags per bp = 0.003956\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 77\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tTotal Tags = 22257432.0\n",
      "\tTags per bp = 0.011129\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 525\n",
      "\tTotal Tags = 24132118.0\n",
      "\tTags per bp = 0.012066\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 67\n",
      "\tTotal Tags = 15183467.0\n",
      "\tTags per bp = 0.007592\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 76\n",
      "\tTotal Tags = 18428481.0\n",
      "\tTags per bp = 0.009214\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 122\n",
      "\tTotal Tags = 19031322.0\n",
      "\tTags per bp = 0.009516\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 60\n",
      "\tTotal Tags = 9202597.0\n",
      "\tTags per bp = 0.004601\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 71\n",
      "\tTotal Tags = 15576423.0\n",
      "\tTags per bp = 0.007788\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 88\n",
      "\tTotal Tags = 14360460.0\n",
      "\tTags per bp = 0.007180\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 77\n",
      "\tTotal Tags = 6389374.0\n",
      "\tTags per bp = 0.003195\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 77\n",
      "\tTotal Tags = 21472882.0\n",
      "\tTags per bp = 0.010736\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 53\n",
      "\tTotal Tags = 13884980.0\n",
      "\tTags per bp = 0.006942\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 67\n",
      "\tTotal Tags = 14924511.0\n",
      "\tTags per bp = 0.007462\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 77\n",
      "\tTotal Tags = 6849708.0\n",
      "\tTags per bp = 0.003425\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFragment Length = 77\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tTotal Tags = 23448604.0\n",
      "\tTags per bp = 0.011724\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 77\n",
      "\tTotal Tags = 14233363.0\n",
      "\tTags per bp = 0.007117\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 71\n",
      "\tTotal Tags = 7272783.0\n",
      "\tTags per bp = 0.003636\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\tFragment Length = 66\n",
      "\tTotal Tags = 9775226.0\n",
      "\tTags per bp = 0.004888\n",
      "\tMax tags per bp set automatically to 1.0\n",
      "\tFinding peaks of size 200, no closer than 400\n",
      "\t\tFinding peaks on chr1 (minCount=0.4), total tags positions = 163295\n",
      "\t\tFinding peaks on chr1 (minCount=0.9), total tags positions = 128882\n",
      "\t\tFinding peaks on chr1 (minCount=-0.5), total tags positions = 236186\n",
      "\t\tFinding peaks on chr1 (minCount=-0.2), total tags positions = 122470\n",
      "\t\tFinding peaks on chr1 (minCount=-0.2), total tags positions = 287901\n",
      "\t\tFinding peaks on chr1 (minCount=0.4), total tags positions = 333975\n",
      "\t\tFinding peaks on chr2 (minCount=0.9), total tags positions = 122848\n",
      "\t\tFinding peaks on chr2 (minCount=0.4), total tags positions = 155252\n",
      "\t\tFinding peaks on chr1 (minCount=-0.4), total tags positions = 277193\n",
      "\t\tFinding peaks on chr3 (minCount=0.9), total tags positions = 98926\n",
      "\t\tFinding peaks on chr1 (minCount=-0.2), total tags positions = 285912\n",
      "\t\tFinding peaks on chr1 (minCount=1.4), total tags positions = 578684\n",
      "\t\tFinding peaks on chr3 (minCount=0.4), total tags positions = 123375\n",
      "\t\tFinding peaks on chr1 (minCount=-0.3), total tags positions = 298063\n",
      "\t\tFinding peaks on chr2 (minCount=-0.2), total tags positions = 118559\n",
      "\t\tFinding peaks on chr1 (minCount=1.4), total tags positions = 612782\n",
      "\t\tFinding peaks on chr4 (minCount=0.9), total tags positions = 99501\n",
      "\t\tFinding peaks on chr1 (minCount=-0.0), total tags positions = 486733\n",
      "\t\tFinding peaks on chr4 (minCount=0.4), total tags positions = 111650\n",
      "\t\tFinding peaks on chr2 (minCount=-0.2), total tags positions = 312710\n",
      "\t\tFinding peaks on chr2 (minCount=-0.5), total tags positions = 241214\n",
      "\t\tFinding peaks on chr1 (minCount=-0.3), total tags positions = 416415\n",
      "\t\tFinding peaks on chr5 (minCount=0.9), total tags positions = 103634\n",
      "\t\tFinding peaks on chr1 (minCount=0.5), total tags positions = 422668\n",
      "\t\tFinding peaks on chr1 (minCount=0.6), total tags positions = 944888\n",
      "\t\tFinding peaks on chr1 (minCount=0.6), total tags positions = 765420\n",
      "\t\tFinding peaks on chr1 (minCount=-0.1), total tags positions = 471910\n",
      "\t\tFinding peaks on chr1 (minCount=0.5), total tags positions = 477222\n",
      "\t\tFinding peaks on chr3 (minCount=-0.2), total tags positions = 94145\n",
      "\t\tFinding peaks on chr6 (minCount=0.9), total tags positions = 98109\n",
      "\t\tFinding peaks on chr5 (minCount=0.4), total tags positions = 117390\n",
      "\t\tFinding peaks on chr1 (minCount=1.1), total tags positions = 1150474\n",
      "\t\tFinding peaks on chr2 (minCount=0.4), total tags positions = 321810\n",
      "\t\tFinding peaks on chr3 (minCount=-0.2), total tags positions = 244927\n",
      "\t\tFinding peaks on chr7 (minCount=0.9), total tags positions = 100306\n",
      "\t\tFinding peaks on chr4 (minCount=-0.2), total tags positions = 92694\n",
      "\t\tFinding peaks on chr6 (minCount=0.4), total tags positions = 113629\n",
      "\t\tFinding peaks on chr2 (minCount=-0.4), total tags positions = 275534\n",
      "\t\tFinding peaks on chr3 (minCount=-0.5), total tags positions = 183945\n",
      "\t\tFinding peaks on chr2 (minCount=-0.2), total tags positions = 289662\n",
      "\t\tFinding peaks on chr1 (minCount=1.2), total tags positions = 1207671\n",
      "\t\tFinding peaks on chr8 (minCount=0.9), total tags positions = 90209\n",
      "\t\tFinding peaks on chr2 (minCount=1.4), total tags positions = 613362\n",
      "\t\tFinding peaks on chr2 (minCount=-0.3), total tags positions = 284864\n",
      "\t\tFinding peaks on chr5 (minCount=-0.2), total tags positions = 94733\n",
      "\t\tFinding peaks on chr4 (minCount=-0.2), total tags positions = 229327\n",
      "\t\tFinding peaks on chr1 (minCount=0.4), total tags positions = 790624\n",
      "\t\tFinding peaks on chr2 (minCount=-0.0), total tags positions = 486172\n",
      "\t\tFinding peaks on chr7 (minCount=0.4), total tags positions = 135924\n",
      "\t\tFinding peaks on chr1 (minCount=1.1), total tags positions = 1123297\n",
      "\t\tFinding peaks on chr3 (minCount=0.4), total tags positions = 270284\n",
      "\t\tFinding peaks on chr1 (minCount=1.3), total tags positions = 1241807\n",
      "\t\tFinding peaks on chr9 (minCount=0.9), total tags positions = 89959\n",
      "\t\tFinding peaks on chr6 (minCount=-0.2), total tags positions = 92974\n",
      "\t\tFinding peaks on chr5 (minCount=-0.2), total tags positions = 238643\n",
      "\t\tFinding peaks on chr1 (minCount=0.7), total tags positions = 951186\n",
      "\t\tFinding peaks on chr4 (minCount=-0.5), total tags positions = 186392\n",
      "\t\tFinding peaks on chr8 (minCount=0.4), total tags positions = 109021\n",
      "\t\tFinding peaks on chr1 (minCount=0.8), total tags positions = 1029045\n",
      "\t\tFinding peaks on chr10 (minCount=0.9), total tags positions = 90277\n",
      "\t\tFinding peaks on chr3 (minCount=-0.4), total tags positions = 223519\n",
      "\t\tFinding peaks on chr7 (minCount=-0.2), total tags positions = 91642\n",
      "\t\tFinding peaks on chr2 (minCount=0.5), total tags positions = 413052\n",
      "\t\tFinding peaks on chr2 (minCount=-0.3), total tags positions = 434227\n",
      "\t\tFinding peaks on chr3 (minCount=-0.2), total tags positions = 215975\n",
      "\t\tFinding peaks on chr3 (minCount=-0.3), total tags positions = 227146\n",
      "\t\tFinding peaks on chr6 (minCount=-0.2), total tags positions = 236339\n",
      "\t\tFinding peaks on chr2 (minCount=1.4), total tags positions = 612131\n",
      "\t\tFinding peaks on chr11 (minCount=0.9), total tags positions = 87660\n",
      "\t\tFinding peaks on chr8 (minCount=-0.2), total tags positions = 79684\n",
      "\t\tFinding peaks on chr4 (minCount=0.4), total tags positions = 238018\n",
      "\t\tFinding peaks on chr9 (minCount=0.4), total tags positions = 113214\n",
      "\t\tFinding peaks on chr2 (minCount=0.5), total tags positions = 517362\n",
      "\t\tFinding peaks on chr5 (minCount=-0.5), total tags positions = 182688\n",
      "\t\tFinding peaks on chr2 (minCount=-0.1), total tags positions = 504881\n",
      "\t\tFinding peaks on chr2 (minCount=0.6), total tags positions = 735633\n",
      "\t\tFinding peaks on chr1 (minCount=1.4), total tags positions = 1263414\n",
      "\t\tFinding peaks on chr7 (minCount=-0.2), total tags positions = 235596\n",
      "\t\tFinding peaks on chr9 (minCount=-0.2), total tags positions = 84710\n",
      "\t\tFinding peaks on chr12 (minCount=0.9), total tags positions = 86671\n",
      "\t\tFinding peaks on chr4 (minCount=-0.3), total tags positions = 227781\n",
      "\t\tFinding peaks on chr4 (minCount=-0.4), total tags positions = 212233\n",
      "\t\tFinding peaks on chr10 (minCount=0.4), total tags positions = 116491\n",
      "\t\tFinding peaks on chr3 (minCount=1.4), total tags positions = 474709\n",
      "\t\tFinding peaks on chr4 (minCount=-0.2), total tags positions = 227699\n",
      "\t\tFinding peaks on chr3 (minCount=-0.0), total tags positions = 378188\n",
      "\t\tFinding peaks on chr10 (minCount=-0.2), total tags positions = 82400\n",
      "\t\tFinding peaks on chr6 (minCount=-0.5), total tags positions = 171469\n",
      "\t\tFinding peaks on chr8 (minCount=-0.2), total tags positions = 207311\n",
      "\t\tFinding peaks on chr13 (minCount=0.9), total tags positions = 79613\n",
      "\t\tFinding peaks on chr2 (minCount=0.6), total tags positions = 991495\n",
      "\t\tFinding peaks on chr5 (minCount=0.4), total tags positions = 238423\n",
      "\t\tFinding peaks on chr11 (minCount=0.4), total tags positions = 120590\n",
      "\t\tFinding peaks on chr11 (minCount=-0.2), total tags positions = 84544\n",
      "\t\tFinding peaks on chr5 (minCount=-0.3), total tags positions = 221138\n",
      "\t\tFinding peaks on chr14 (minCount=0.9), total tags positions = 69297\n",
      "\t\tFinding peaks on chr3 (minCount=1.4), total tags positions = 501916\n",
      "\t\tFinding peaks on chr9 (minCount=-0.2), total tags positions = 204330\n",
      "\t\tFinding peaks on chr3 (minCount=0.5), total tags positions = 345176\n",
      "\t\tFinding peaks on chr3 (minCount=-0.3), total tags positions = 318959\n",
      "\t\tFinding peaks on chr2 (minCount=1.2), total tags positions = 1266973\n",
      "\t\tFinding peaks on chr12 (minCount=-0.2), total tags positions = 69536\n",
      "\t\tFinding peaks on chr5 (minCount=-0.4), total tags positions = 215441\n",
      "\t\tFinding peaks on chr15 (minCount=0.9), total tags positions = 70815\n",
      "\t\tFinding peaks on chr7 (minCount=-0.5), total tags positions = 193067\n",
      "\t\tFinding peaks on chr12 (minCount=0.4), total tags positions = 111707\n",
      "\t\tFinding peaks on chr5 (minCount=-0.2), total tags positions = 222638\n",
      "\t\tFinding peaks on chr10 (minCount=-0.2), total tags positions = 220005\n",
      "\t\tFinding peaks on chr13 (minCount=-0.2), total tags positions = 76062\n",
      "\t\tFinding peaks on chr16 (minCount=0.9), total tags positions = 57661\n",
      "\t\tFinding peaks on chr3 (minCount=-0.1), total tags positions = 379783\n",
      "\t\tFinding peaks on chr3 (minCount=0.5), total tags positions = 400100\n",
      "\t\tFinding peaks on chr2 (minCount=0.7), total tags positions = 993996\n",
      "\t\tFinding peaks on chr6 (minCount=-0.3), total tags positions = 208553\n",
      "\t\tFinding peaks on chr14 (minCount=-0.2), total tags positions = 69398\n",
      "\t\tFinding peaks on chr13 (minCount=0.4), total tags positions = 102949\n",
      "\t\tFinding peaks on chr11 (minCount=-0.2), total tags positions = 216131\n",
      "\t\tFinding peaks on chr17 (minCount=0.9), total tags positions = 65796\n",
      "\t\tFinding peaks on chr6 (minCount=0.4), total tags positions = 247649\n",
      "\t\tFinding peaks on chr2 (minCount=0.4), total tags positions = 825972\n",
      "\t\tFinding peaks on chr8 (minCount=-0.5), total tags positions = 165443\n",
      "\t\tFinding peaks on chr6 (minCount=-0.4), total tags positions = 209702\n",
      "\t\tFinding peaks on chr4 (minCount=1.4), total tags positions = 475590\n",
      "\t\tFinding peaks on chr15 (minCount=-0.2), total tags positions = 62697\n",
      "\t\tFinding peaks on chr18 (minCount=0.9), total tags positions = 60930\n",
      "\t\tFinding peaks on chr1 (minCount=3.6), total tags positions = 2050087\n",
      "\t\tFinding peaks on chr4 (minCount=-0.0), total tags positions = 390907\n",
      "\t\tFinding peaks on chr12 (minCount=-0.2), total tags positions = 187780\n",
      "\t\tFinding peaks on chr14 (minCount=0.4), total tags positions = 90528\n",
      "\t\tFinding peaks on chr6 (minCount=-0.2), total tags positions = 213815\n",
      "\t\tFinding peaks on chr19 (minCount=0.9), total tags positions = 37075\n",
      "\t\tFinding peaks on chr16 (minCount=-0.2), total tags positions = 58145\n",
      "\t\tFinding peaks on chr4 (minCount=0.5), total tags positions = 311177\n",
      "\t\tFinding peaks on chr2 (minCount=1.1), total tags positions = 1204202\n",
      "\t\tFinding peaks on chr4 (minCount=-0.3), total tags positions = 332219\n",
      "\t\tFinding peaks on chr3 (minCount=0.6), total tags positions = 597799\n",
      "\t\tFinding peaks on chrX (minCount=0.9), total tags positions = 47602\n",
      "\t\tFinding peaks on chr4 (minCount=1.4), total tags positions = 479044\n",
      "\t\tFinding peaks on chr17 (minCount=-0.2), total tags positions = 62107\n",
      "\t\tFinding peaks on chr7 (minCount=-0.3), total tags positions = 224993\n",
      "\t\tFinding peaks on chr15 (minCount=0.4), total tags positions = 77599\n",
      "\t\tFinding peaks on chrY (minCount=0.9), total tags positions = 2279\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.9), total tags positions = 36\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.9), total tags positions = 59\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.9), total tags positions = 37\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.9), total tags positions = 34\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.9), total tags positions = 46\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.9), total tags positions = 8\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.9), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.9), total tags positions = 6\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.9), total tags positions = 2\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.9), total tags positions = 3\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.9), total tags positions = 38\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.9), total tags positions = 90\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.9), total tags positions = 11\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.9), total tags positions = 17\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.9), total tags positions = 49\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.9), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.9), total tags positions = 3\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.9), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.9), total tags positions = 8\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.9), total tags positions = 21\n",
      "\t\tFinding peaks on chr13 (minCount=-0.2), total tags positions = 197840\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.9), total tags positions = 12\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.9), total tags positions = 18\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.9), total tags positions = 8\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.9), total tags positions = 44\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.9), total tags positions = 8\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.9), total tags positions = 35\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.9), total tags positions = 83\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.9), total tags positions = 34\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.9), total tags positions = 276\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.9), total tags positions = 51\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.9), total tags positions = 9\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.9), total tags positions = 21\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.9), total tags positions = 1558\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.9), total tags positions = 57\n",
      "\t\tFinding peaks on chrY_JH584300_random (minCount=0.9), total tags positions = 1\n",
      "\t\tFinding peaks on chr9 (minCount=-0.5), total tags positions = 155478\n",
      "\t\tFinding peaks on chr18 (minCount=-0.2), total tags positions = 56943\n",
      "\t\tFinding peaks on chr7 (minCount=0.4), total tags positions = 225095\n",
      "\t\tFinding peaks on chr7 (minCount=-0.4), total tags positions = 208356\n",
      "\t\tFinding peaks on chr16 (minCount=0.4), total tags positions = 83144\n",
      "\t\tFinding peaks on chr14 (minCount=-0.2), total tags positions = 178065\n",
      "\t\tFinding peaks on chr19 (minCount=-0.2), total tags positions = 39611\n",
      "\t\tFinding peaks on chr4 (minCount=-0.1), total tags positions = 375969\n",
      "\t\tFinding peaks on chr4 (minCount=0.5), total tags positions = 383355\n",
      "\t\tFinding peaks on chr2 (minCount=1.1), total tags positions = 1192006\n",
      "\t\tFinding peaks on chr7 (minCount=-0.2), total tags positions = 211139\n",
      "\t\tFinding peaks on chrX (minCount=-0.2), total tags positions = 36999\n",
      "\t\tFinding peaks on chrY (minCount=-0.2), total tags positions = 1297\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=-0.2), total tags positions = 36\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=-0.2), total tags positions = 41\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=-0.2), total tags positions = 21\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=-0.2), total tags positions = 26\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=-0.2), total tags positions = 106\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=-0.2), total tags positions = 10\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=-0.2), total tags positions = 4\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=-0.2), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=-0.2), total tags positions = 2\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=-0.2), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=-0.2), total tags positions = 25\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=-0.2), total tags positions = 80\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=-0.2), total tags positions = 48\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=-0.2), total tags positions = 5\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=-0.2), total tags positions = 15\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=-0.2), total tags positions = 7\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=-0.2), total tags positions = 5\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=-0.2), total tags positions = 2\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=-0.2), total tags positions = 9\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=-0.2), total tags positions = 16\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=-0.2), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=-0.2), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=-0.2), total tags positions = 4\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=-0.2), total tags positions = 24\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=-0.2), total tags positions = 15\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=-0.2), total tags positions = 27\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=-0.2), total tags positions = 58\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=-0.2), total tags positions = 27\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=-0.2), total tags positions = 191\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=-0.2), total tags positions = 47\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=-0.2), total tags positions = 7\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=-0.2), total tags positions = 20\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=-0.2), total tags positions = 1497\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=-0.2), total tags positions = 80\n",
      "\t\tFinding peaks on chr10 (minCount=-0.5), total tags positions = 164741\n",
      "\t\tFinding peaks on chr15 (minCount=-0.2), total tags positions = 165936\n",
      "\t\tFinding peaks on chr17 (minCount=0.4), total tags positions = 83275\n",
      "\t\tFinding peaks on chr8 (minCount=0.4), total tags positions = 203619\n",
      "\t\tFinding peaks on chr2 (minCount=0.8), total tags positions = 1065447\n",
      "\t\tFinding peaks on chr8 (minCount=-0.3), total tags positions = 201052\n",
      "\t\tFinding peaks on chr3 (minCount=0.6), total tags positions = 717631\n",
      "\t\tFinding peaks on chr2 (minCount=1.3), total tags positions = 1300953\n",
      "\t\tFinding peaks on chr5 (minCount=0.5), total tags positions = 314402\n",
      "\t\tFinding peaks on chr18 (minCount=0.4), total tags positions = 85578\n",
      "\t\tFinding peaks on chr3 (minCount=1.2), total tags positions = 924699\n",
      "\t\tFinding peaks on chr5 (minCount=-0.3), total tags positions = 329931\n",
      "\t\tFinding peaks on chr16 (minCount=-0.2), total tags positions = 156271\n",
      "\t\tFinding peaks on chr8 (minCount=-0.4), total tags positions = 186772\n",
      "\t\tFinding peaks on chr3 (minCount=0.4), total tags positions = 602647\n",
      "\t\tFinding peaks on chr19 (minCount=0.4), total tags positions = 52139\n",
      "\t\tFinding peaks on chr5 (minCount=1.4), total tags positions = 465097\n",
      "\t\tFinding peaks on chr5 (minCount=-0.0), total tags positions = 400478\n",
      "\t\tFinding peaks on chrX (minCount=0.4), total tags positions = 56457\n",
      "\t\tFinding peaks on chr8 (minCount=-0.2), total tags positions = 188239\n",
      "\t\tFinding peaks on chrY (minCount=0.4), total tags positions = 2236\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.4), total tags positions = 41\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.4), total tags positions = 55\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.4), total tags positions = 38\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.4), total tags positions = 38\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.4), total tags positions = 85\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.4), total tags positions = 12\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.4), total tags positions = 7\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.4), total tags positions = 4\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.4), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.4), total tags positions = 25\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.4), total tags positions = 91\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.4), total tags positions = 33\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.4), total tags positions = 26\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.4), total tags positions = 29\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.4), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.4), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.4), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.4), total tags positions = 12\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.4), total tags positions = 26\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.4), total tags positions = 17\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.4), total tags positions = 7\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.4), total tags positions = 5\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.4), total tags positions = 26\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.4), total tags positions = 13\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.4), total tags positions = 27\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.4), total tags positions = 64\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.4), total tags positions = 22\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.4), total tags positions = 221\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.4), total tags positions = 67\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.4), total tags positions = 8\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.4), total tags positions = 24\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.4), total tags positions = 1846\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.4), total tags positions = 108\n",
      "\t\tFinding peaks on chr17 (minCount=-0.2), total tags positions = 170749\n",
      "\t\tFinding peaks on chr11 (minCount=-0.5), total tags positions = 182516\n",
      "\t\tFinding peaks on chr9 (minCount=0.4), total tags positions = 211125\n",
      "\t\tFinding peaks on chr9 (minCount=-0.3), total tags positions = 199592\n",
      "\t\tFinding peaks on chr5 (minCount=1.4), total tags positions = 475746\n",
      "\t\tFinding peaks on chr18 (minCount=-0.2), total tags positions = 141097\n",
      "\t\tTags Used for cluster (less clonal tags) = 1690758.0 / 19031322.0\n",
      "\tExpected tags per peak = 0.169076 (tbp = 0.000845)\n",
      "\t\tTags Used for cluster (less clonal tags) = 1573831.0 / 7825213.0\n",
      "\tExpected tags per peak = 0.157383 (tbp = 0.000787)\n",
      "\t\tFinding peaks on chr9 (minCount=-0.4), total tags positions = 190465\n",
      "\t\tFinding peaks on chr19 (minCount=-0.2), total tags positions = 101571\n",
      "\t\tFinding peaks on chr5 (minCount=0.5), total tags positions = 393590\n",
      "\t\tFinding peaks on chr12 (minCount=-0.5), total tags positions = 131151\n",
      "\t\tFinding peaks on chr5 (minCount=-0.1), total tags positions = 382865\n",
      "\t\tFinding peaks on chr3 (minCount=1.1), total tags positions = 872260\n",
      "\t\tFinding peaks on chr6 (minCount=0.5), total tags positions = 319764\n",
      "\t\tFinding peaks on chr4 (minCount=0.6), total tags positions = 605594\n",
      "\t\tFinding peaks on chr9 (minCount=-0.2), total tags positions = 200691\n",
      "\t\tFinding peaks on chr3 (minCount=0.7), total tags positions = 720276\n",
      "\t\tFinding peaks on chr2 (minCount=1.4), total tags positions = 1316650\n",
      "\t\tFinding peaks on chrX (minCount=-0.2), total tags positions = 93174\n",
      "\t\tFinding peaks on chrY (minCount=-0.2), total tags positions = 3212\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=-0.2), total tags positions = 37\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=-0.2), total tags positions = 84\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=-0.2), total tags positions = 48\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=-0.2), total tags positions = 49\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=-0.2), total tags positions = 267\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=-0.2), total tags positions = 13\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=-0.2), total tags positions = 7\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=-0.2), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=-0.2), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=-0.2), total tags positions = 39\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=-0.2), total tags positions = 135\n",
      "\t\tFinding peaks on chr10 (minCount=0.4), total tags positions = 226142\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=-0.2), total tags positions = 102\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=-0.2), total tags positions = 33\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=-0.2), total tags positions = 34\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=-0.2), total tags positions = 5\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=-0.2), total tags positions = 7\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=-0.2), total tags positions = 8\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=-0.2), total tags positions = 12\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=-0.2), total tags positions = 19\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=-0.2), total tags positions = 16\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=-0.2), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=-0.2), total tags positions = 7\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=-0.2), total tags positions = 70\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=-0.2), total tags positions = 25\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=-0.2), total tags positions = 60\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=-0.2), total tags positions = 64\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=-0.2), total tags positions = 35\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=-0.2), total tags positions = 264\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=-0.2), total tags positions = 67\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=-0.2), total tags positions = 18\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=-0.2), total tags positions = 34\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=-0.2), total tags positions = 2847\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=-0.2), total tags positions = 206\n",
      "\t\tFinding peaks on chr6 (minCount=-0.3), total tags positions = 324776\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t5\t25851.000\t14.118\t5.46e-04\t7.06e-07\n",
      "\t\t4\t35318.000\t450.936\t1.28e-02\t2.25e-05\n",
      "\t\t3\t59754.000\t11552.967\t1.93e-01\t5.78e-04\n",
      "\t\t2\t186492.000\t223177.286\t1.00e+00\t1.12e-02\n",
      "\t\t1\t946120.000\t2912466.298\t1.00e+00\t1.46e-01\n",
      "\t\t0\t946120.000\t19999999.999\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 5.78e-04)\n",
      "\t\tFinding peaks on chr10 (minCount=-0.3), total tags positions = 205748\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t6\t2942.000\t0.561\t1.91e-04\t2.81e-08\n",
      "\t\t5\t5880.000\t20.007\t3.40e-03\t1.00e-06\n",
      "\t\t4\t15346.000\t595.071\t3.88e-02\t2.98e-05\n",
      "\t\t3\t58787.000\t14199.942\t2.42e-01\t7.10e-04\n",
      "\t\t2\t268086.000\t255598.251\t9.53e-01\t1.28e-02\n",
      "\t\t1\t1098415.000\t3111102.192\t1.00e+00\t1.56e-01\n",
      "\t\t0\t1098415.000\t19999999.999\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 7.10e-04)\n",
      "\t\tFinding peaks on chr4 (minCount=0.4), total tags positions = 666066\n",
      "\t\tFinding peaks on chr13 (minCount=-0.5), total tags positions = 138686\n",
      "\t\tFinding peaks on chr6 (minCount=1.4), total tags positions = 423530\n",
      "\t\tFinding peaks on chr10 (minCount=-0.4), total tags positions = 198110\n",
      "\t\tFinding peaks on chr6 (minCount=-0.0), total tags positions = 377908\n",
      "\t\tFinding peaks on chr3 (minCount=1.1), total tags positions = 850306\n",
      "\t59754 peaks passed threshold\n",
      "\t\tFinding peaks on chr10 (minCount=-0.2), total tags positions = 200070\n",
      "\t\tFinding peaks on chr6 (minCount=-0.1), total tags positions = 374491\n",
      "\t\tFinding peaks on chr11 (minCount=0.4), total tags positions = 208703\n",
      "\t\tFinding peaks on chr6 (minCount=0.5), total tags positions = 382590\n",
      "\t\tFinding peaks on chr3 (minCount=1.3), total tags positions = 949628\n",
      "\t\tFinding peaks on chr14 (minCount=-0.5), total tags positions = 122790\n",
      "\t58787 peaks passed threshold\n",
      "\t\tFinding peaks on chr7 (minCount=0.5), total tags positions = 292651\n",
      "\t\tFinding peaks on chr11 (minCount=-0.3), total tags positions = 201422\n",
      "\t\tFinding peaks on chr6 (minCount=1.4), total tags positions = 466181\n",
      "\t\tTags Used for cluster (less clonal tags) = 2128451.0 / 13884980.0\n",
      "\tExpected tags per peak = 0.212845 (tbp = 0.001064)\n",
      "\t\tFinding peaks on chr11 (minCount=-0.4), total tags positions = 187000\n",
      "\t\tTags Used for cluster (less clonal tags) = 4033543.0 / 7912771.0\n",
      "\tExpected tags per peak = 0.403354 (tbp = 0.002017)\n",
      "\t\tFinding peaks on chr15 (minCount=-0.5), total tags positions = 121675\n",
      "\t\tFinding peaks on chr7 (minCount=-0.3), total tags positions = 326963\n",
      "\t\tFinding peaks on chr11 (minCount=-0.2), total tags positions = 200666\n",
      "\t\tFinding peaks on chr5 (minCount=0.4), total tags positions = 678457\n",
      "\t\tFinding peaks on chr12 (minCount=0.4), total tags positions = 185861\n",
      "\t\tFinding peaks on chr4 (minCount=0.6), total tags positions = 809144\n",
      "\t\tFinding peaks on chr12 (minCount=-0.3), total tags positions = 168273\n",
      "\t\tFinding peaks on chr3 (minCount=0.8), total tags positions = 793631\n",
      "\t\tFinding peaks on chr16 (minCount=-0.5), total tags positions = 107194\n",
      "\t\tFinding peaks on chr8 (minCount=0.5), total tags positions = 266658\n",
      "\t\tFinding peaks on chr12 (minCount=-0.4), total tags positions = 164471\n",
      "\t\tFinding peaks on chr7 (minCount=1.4), total tags positions = 476475\n",
      "\t\tFinding peaks on chr7 (minCount=-0.1), total tags positions = 381465\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t7\t51717.000\t4.848\t9.37e-05\t2.42e-07\n",
      "\t\t6\t60501.000\t84.766\t1.40e-03\t4.24e-06\n",
      "\t\t5\t74095.000\t1273.563\t1.72e-02\t6.37e-05\n",
      "\t\t4\t102487.000\t16009.950\t1.56e-01\t8.00e-04\n",
      "\t\t3\t196175.000\t162148.337\t8.27e-01\t8.11e-03\n",
      "\t\t2\t565065.000\t1249071.550\t1.00e+00\t6.25e-02\n",
      "\t\t1\t1644973.000\t6638493.055\t1.00e+00\t3.32e-01\n",
      "\t\t0\t1644973.000\t19999999.994\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 8.11e-03)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t6\t16575.000\t2.153\t1.30e-04\t1.08e-07\n",
      "\t\t5\t22927.000\t61.000\t2.66e-03\t3.05e-06\n",
      "\t\t4\t37152.000\t1443.407\t3.89e-02\t7.22e-05\n",
      "\t\t3\t88981.000\t27422.990\t3.08e-01\t1.37e-03\n",
      "\t\t2\t325244.000\t393598.937\t1.00e+00\t1.97e-02\n",
      "\t\t1\t1222954.000\t3834373.183\t1.00e+00\t1.92e-01\n",
      "\t\t0\t1222954.000\t19999999.999\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 1.37e-03)\n",
      "\t\tFinding peaks on chr3 (minCount=1.4), total tags positions = 961230\n",
      "\t\tFinding peaks on chr7 (minCount=0.5), total tags positions = 374443\n",
      "\t\tFinding peaks on chr5 (minCount=0.6), total tags positions = 596308\n",
      "\t\tFinding peaks on chr7 (minCount=-0.0), total tags positions = 387951\n",
      "\t\tFinding peaks on chr12 (minCount=-0.2), total tags positions = 164911\n",
      "\t\tFinding peaks on chr17 (minCount=-0.5), total tags positions = 127039\n",
      "\t\tFinding peaks on chr13 (minCount=0.4), total tags positions = 201765\n",
      "\t\tFinding peaks on chr4 (minCount=1.2), total tags positions = 1043955\n",
      "\t\tFinding peaks on chr13 (minCount=-0.3), total tags positions = 196041\n",
      "\t196175 peaks passed threshold\n",
      "\t\tFinding peaks on chr8 (minCount=-0.3), total tags positions = 270650\n",
      "\t\tFinding peaks on chr13 (minCount=-0.4), total tags positions = 181020\n",
      "\t\tFinding peaks on chr18 (minCount=-0.5), total tags positions = 104071\n",
      "\t88981 peaks passed threshold\n",
      "\t\tFinding peaks on chr7 (minCount=1.4), total tags positions = 460940\n",
      "\t\tFinding peaks on chr4 (minCount=1.3), total tags positions = 1062758\n",
      "\t\tFinding peaks on chr9 (minCount=0.5), total tags positions = 273086\n",
      "\t\tFinding peaks on chr4 (minCount=1.1), total tags positions = 982158\n",
      "\t\tFinding peaks on chr4 (minCount=0.7), total tags positions = 814638\n",
      "\t\tFinding peaks on chr19 (minCount=-0.5), total tags positions = 86906\n",
      "\t\tFinding peaks on chr13 (minCount=-0.2), total tags positions = 175011\n",
      "\t\tFinding peaks on chr6 (minCount=0.4), total tags positions = 599382\n",
      "\t\tFinding peaks on chrX (minCount=-0.5), total tags positions = 68425\n",
      "\t\tFinding peaks on chrY (minCount=-0.5), total tags positions = 1383\n",
      "\t\tFinding peaks on chr8 (minCount=-0.1), total tags positions = 331432\n",
      "\t\tFinding peaks on chr14 (minCount=-0.3), total tags positions = 162173\n",
      "\t\tFinding peaks on chr9 (minCount=-0.3), total tags positions = 285332\n",
      "\t\tFinding peaks on chr14 (minCount=0.4), total tags positions = 184281\n",
      "\t\tFinding peaks on chr8 (minCount=0.5), total tags positions = 340431\n",
      "\t\tFinding peaks on chr14 (minCount=-0.4), total tags positions = 156548\n",
      "\t\tFinding peaks on chr8 (minCount=1.4), total tags positions = 395410\n",
      "\t\tFinding peaks on chr8 (minCount=-0.0), total tags positions = 334902\n",
      "\t\tFinding peaks on chr14 (minCount=-0.2), total tags positions = 165210\n",
      "\t\tFinding peaks on chr15 (minCount=-0.3), total tags positions = 148945\n",
      "\t\tFinding peaks on chr10 (minCount=-0.3), total tags positions = 303404\n",
      "\t\tFinding peaks on chr15 (minCount=-0.4), total tags positions = 145107\n",
      "\t\tFinding peaks on chr15 (minCount=0.4), total tags positions = 163007\n",
      "\t\tFinding peaks on chr4 (minCount=1.1), total tags positions = 965031\n",
      "\t\tFinding peaks on chr10 (minCount=0.5), total tags positions = 291663\n",
      "\t\tFinding peaks on chr15 (minCount=-0.2), total tags positions = 142792\n",
      "\t\tFinding peaks on chr6 (minCount=0.6), total tags positions = 596668\n",
      "\t\tFinding peaks on chr8 (minCount=1.4), total tags positions = 397523\n",
      "\t\tFinding peaks on chr9 (minCount=0.5), total tags positions = 325213\n",
      "\t\tFinding peaks on chr16 (minCount=-0.3), total tags positions = 143249\n",
      "\t\tTags Used for cluster (less clonal tags) = 3072459.0 / 5063449.0\n",
      "\tExpected tags per peak = 0.307246 (tbp = 0.001536)\n",
      "\t\tFinding peaks on chr9 (minCount=-0.1), total tags positions = 351579\n",
      "\t\tFinding peaks on chr16 (minCount=-0.4), total tags positions = 133559\n",
      "\t\tFinding peaks on chr16 (minCount=0.4), total tags positions = 160344\n",
      "\t\tFinding peaks on chr11 (minCount=-0.3), total tags positions = 309874\n",
      "\t\tFinding peaks on chr5 (minCount=0.6), total tags positions = 826280\n",
      "\t\tFinding peaks on chr5 (minCount=1.3), total tags positions = 1084746\n",
      "\t\tFinding peaks on chr16 (minCount=-0.2), total tags positions = 139101\n",
      "\t\tFinding peaks on chr7 (minCount=0.4), total tags positions = 659726\n",
      "\t\tFinding peaks on chr9 (minCount=-0.0), total tags positions = 337857\n",
      "\t\tFinding peaks on chr9 (minCount=1.4), total tags positions = 423209\n",
      "\t\tFinding peaks on chr4 (minCount=0.8), total tags positions = 875339\n",
      "\t\tFinding peaks on chr17 (minCount=-0.4), total tags positions = 142035\n",
      "\t\tFinding peaks on chr17 (minCount=-0.3), total tags positions = 149254\n",
      "\t\tFinding peaks on chr2 (minCount=3.6), total tags positions = 2136911\n",
      "\t\tFinding peaks on chr11 (minCount=0.5), total tags positions = 273016\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t6\t45626.000\t17.970\t3.94e-04\t8.99e-07\n",
      "\t\t5\t56144.000\t353.588\t6.30e-03\t1.77e-05\n",
      "\t\t4\t74081.000\t5815.289\t7.85e-02\t2.91e-04\n",
      "\t\t3\t119557.000\t76920.572\t6.43e-01\t3.85e-03\n",
      "\t\t2\t316460.000\t771204.348\t1.00e+00\t3.86e-02\n",
      "\t\t1\t1191323.000\t5290605.613\t1.00e+00\t2.65e-01\n",
      "\t\t0\t1191323.000\t19999999.997\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 3.85e-03)\n",
      "\t\tFinding peaks on chr17 (minCount=0.4), total tags positions = 155212\n",
      "\t\tFinding peaks on chr12 (minCount=-0.3), total tags positions = 248719\n",
      "\t\tFinding peaks on chr17 (minCount=-0.2), total tags positions = 138404\n",
      "\t\tFinding peaks on chr10 (minCount=0.5), total tags positions = 331792\n",
      "\t\tFinding peaks on chr4 (minCount=1.4), total tags positions = 1073888\n",
      "\t\tFinding peaks on chr18 (minCount=-0.3), total tags positions = 132787\n",
      "\t\tFinding peaks on chr18 (minCount=-0.4), total tags positions = 134457\n",
      "\t119557 peaks passed threshold\n",
      "\t\tFinding peaks on chr5 (minCount=1.1), total tags positions = 1004171\n",
      "\t\tFinding peaks on chr9 (minCount=1.4), total tags positions = 424881\n",
      "\t\tFinding peaks on chr18 (minCount=0.4), total tags positions = 151742\n",
      "\t\tFinding peaks on chr10 (minCount=-0.1), total tags positions = 349817\n",
      "\t\tFinding peaks on chr18 (minCount=-0.2), total tags positions = 131186\n",
      "\t\tFinding peaks on chr5 (minCount=0.7), total tags positions = 825175\n",
      "\t\tFinding peaks on chr8 (minCount=0.4), total tags positions = 575041\n",
      "\t\tFinding peaks on chr19 (minCount=-0.4), total tags positions = 91579\n",
      "\t\tFinding peaks on chr19 (minCount=-0.3), total tags positions = 96097\n",
      "\t\tFinding peaks on chr12 (minCount=0.5), total tags positions = 240661\n",
      "\t\tFinding peaks on chr10 (minCount=-0.0), total tags positions = 345631\n",
      "\t\tFinding peaks on chr13 (minCount=-0.3), total tags positions = 261601\n",
      "\t\tFinding peaks on chr5 (minCount=1.2), total tags positions = 1057037\n",
      "\t\tFinding peaks on chr19 (minCount=0.4), total tags positions = 103032\n",
      "\t\tFinding peaks on chr19 (minCount=-0.2), total tags positions = 99768\n",
      "\t\tFinding peaks on chr7 (minCount=0.6), total tags positions = 557236\n",
      "\t\tFinding peaks on chrX (minCount=-0.4), total tags positions = 91173\n",
      "\t\tFinding peaks on chrX (minCount=-0.3), total tags positions = 90701\n",
      "\t\tFinding peaks on chr10 (minCount=1.4), total tags positions = 424633\n",
      "\t\tFinding peaks on chr6 (minCount=1.3), total tags positions = 959927\n",
      "\t\tFinding peaks on chrY (minCount=-0.4), total tags positions = 2680\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=-0.4), total tags positions = 50\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=-0.4), total tags positions = 69\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=-0.4), total tags positions = 57\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=-0.4), total tags positions = 43\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=-0.4), total tags positions = 230\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=-0.4), total tags positions = 19\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=-0.4), total tags positions = 4\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=-0.4), total tags positions = 2\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=-0.4), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=-0.4), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=-0.4), total tags positions = 43\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=-0.4), total tags positions = 133\n",
      "\t\tFinding peaks on chrY (minCount=-0.3), total tags positions = 3086\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=-0.4), total tags positions = 93\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=-0.4), total tags positions = 20\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=-0.4), total tags positions = 40\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=-0.4), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=-0.4), total tags positions = 25\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=-0.3), total tags positions = 64\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=-0.4), total tags positions = 8\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=-0.3), total tags positions = 85\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=-0.4), total tags positions = 17\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=-0.3), total tags positions = 62\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=-0.4), total tags positions = 34\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=-0.3), total tags positions = 61\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=-0.4), total tags positions = 21\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=-0.4), total tags positions = 13\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=-0.3), total tags positions = 277\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=-0.4), total tags positions = 3\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=-0.3), total tags positions = 24\n",
      "\t\tFinding peaks on chr4_JH584293_random (minCount=-0.3), total tags positions = 1\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=-0.3), total tags positions = 8\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=-0.4), total tags positions = 55\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=-0.4), total tags positions = 17\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=-0.3), total tags positions = 6\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=-0.4), total tags positions = 53\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=-0.3), total tags positions = 1\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=-0.4), total tags positions = 78\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=-0.3), total tags positions = 4\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=-0.3), total tags positions = 55\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=-0.4), total tags positions = 36\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=-0.3), total tags positions = 181\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=-0.4), total tags positions = 273\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=-0.3), total tags positions = 99\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=-0.4), total tags positions = 94\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=-0.3), total tags positions = 23\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=-0.4), total tags positions = 9\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=-0.3), total tags positions = 34\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=-0.4), total tags positions = 28\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=-0.3), total tags positions = 23\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=-0.3), total tags positions = 20\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=-0.3), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=-0.3), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=-0.4), total tags positions = 2684\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=-0.3), total tags positions = 42\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=-0.3), total tags positions = 21\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=-0.3), total tags positions = 19\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=-0.3), total tags positions = 11\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=-0.4), total tags positions = 171\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=-0.3), total tags positions = 94\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=-0.3), total tags positions = 24\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=-0.3), total tags positions = 55\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=-0.3), total tags positions = 104\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=-0.3), total tags positions = 53\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=-0.3), total tags positions = 326\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=-0.3), total tags positions = 95\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=-0.3), total tags positions = 18\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=-0.3), total tags positions = 45\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=-0.3), total tags positions = 3128\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=-0.3), total tags positions = 207\n",
      "\t\tFinding peaks on chrX (minCount=-0.2), total tags positions = 90258\n",
      "\t\tFinding peaks on chr11 (minCount=0.5), total tags positions = 346562\n",
      "\t\tFinding peaks on chrY (minCount=-0.2), total tags positions = 2871\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=-0.2), total tags positions = 62\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=-0.2), total tags positions = 99\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=-0.2), total tags positions = 59\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=-0.2), total tags positions = 67\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=-0.2), total tags positions = 273\n",
      "\t\tFinding peaks on chr4_GL456350_random (minCount=-0.2), total tags positions = 1\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=-0.2), total tags positions = 14\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=-0.2), total tags positions = 8\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=-0.2), total tags positions = 12\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=-0.2), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=-0.2), total tags positions = 5\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=-0.2), total tags positions = 56\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=-0.2), total tags positions = 175\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=-0.2), total tags positions = 87\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=-0.2), total tags positions = 30\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=-0.2), total tags positions = 23\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=-0.2), total tags positions = 15\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=-0.2), total tags positions = 11\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=-0.2), total tags positions = 11\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=-0.2), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=-0.2), total tags positions = 30\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=-0.2), total tags positions = 19\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=-0.2), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=-0.2), total tags positions = 10\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=-0.2), total tags positions = 41\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=-0.2), total tags positions = 11\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=-0.2), total tags positions = 38\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=-0.2), total tags positions = 68\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=-0.2), total tags positions = 38\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=-0.2), total tags positions = 226\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=-0.2), total tags positions = 74\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=-0.2), total tags positions = 16\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=-0.2), total tags positions = 31\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=-0.2), total tags positions = 2590\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=-0.2), total tags positions = 202\n",
      "\t\tFinding peaks on chrX (minCount=0.4), total tags positions = 180845\n",
      "\t\tFinding peaks on chr6 (minCount=0.6), total tags positions = 723636\n",
      "\t\tFinding peaks on chr9 (minCount=0.4), total tags positions = 576244\n",
      "\t\tFinding peaks on chr13 (minCount=0.5), total tags positions = 259765\n",
      "\t\tFinding peaks on chr14 (minCount=-0.3), total tags positions = 230891\n",
      "\t\tFinding peaks on chrY (minCount=0.4), total tags positions = 287\n",
      "\tTotal Peaks identified = 59754\n",
      "\t\tFinding peaks on chr11 (minCount=-0.1), total tags positions = 374383\n",
      "\t\tFinding peaks on chr10 (minCount=1.4), total tags positions = 443980\n",
      "\t\tFinding peaks on chr5 (minCount=1.1), total tags positions = 984383\n",
      "\tCentering peaks of size 200 using a fragment length of 67\n",
      "\t\tFinding peaks on chr11 (minCount=-0.0), total tags positions = 369383\n",
      "\t\tFinding peaks on chr5 (minCount=0.8), total tags positions = 889743\n",
      "\t\tFinding peaks on chr12 (minCount=0.5), total tags positions = 305187\n",
      "\t\tFinding peaks on chr11 (minCount=1.4), total tags positions = 441156\n",
      "\t\tFinding peaks on chr14 (minCount=0.5), total tags positions = 235629\n",
      "\t\tFinding peaks on chr10 (minCount=0.4), total tags positions = 556976\n",
      "\t\tFinding peaks on chr15 (minCount=-0.3), total tags positions = 221439\n",
      "\tTotal Peaks identified = 58787\n",
      "\t\tFinding peaks on chr8 (minCount=0.6), total tags positions = 520230\n",
      "\t\tFinding peaks on chr7 (minCount=1.3), total tags positions = 1050411\n",
      "\t\tFinding peaks on chr12 (minCount=-0.1), total tags positions = 279371\n",
      "\tCentering peaks of size 200 using a fragment length of 122\n",
      "\t\tFinding peaks on chr6 (minCount=1.1), total tags positions = 888816\n",
      "\t\tFinding peaks on chr6 (minCount=0.7), total tags positions = 732709\n",
      "\t\tTags Used for cluster (less clonal tags) = 3631392.0 / 6389374.0\n",
      "\tExpected tags per peak = 0.363139 (tbp = 0.001816)\n",
      "\t\tFinding peaks on chr5 (minCount=1.4), total tags positions = 1105367\n",
      "\t\tFinding peaks on chr11 (minCount=1.4), total tags positions = 423963\n",
      "\t\tFinding peaks on chr12 (minCount=-0.0), total tags positions = 280162\n",
      "\t\tTags Used for cluster (less clonal tags) = 3796256.0 / 6849708.0\n",
      "\tExpected tags per peak = 0.379626 (tbp = 0.001898)\n",
      "\t\tFinding peaks on chr15 (minCount=0.5), total tags positions = 214845\n",
      "\t\tFinding peaks on chr6 (minCount=1.2), total tags positions = 927601\n",
      "\t\tFinding peaks on chr16 (minCount=-0.3), total tags positions = 205220\n",
      "\t\tTags Used for cluster (less clonal tags) = 3710445.0 / 7718694.0\n",
      "\tExpected tags per peak = 0.371045 (tbp = 0.001855)\n",
      "\t\tFinding peaks on chr13 (minCount=0.5), total tags positions = 308550\n",
      "\t\tFinding peaks on chr12 (minCount=1.4), total tags positions = 354419\n",
      "\t\tFinding peaks on chr11 (minCount=0.4), total tags positions = 632319\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t6\t60071.000\t46.709\t7.78e-04\t2.34e-06\n",
      "\t\t5\t71774.000\t778.699\t1.08e-02\t3.89e-05\n",
      "\t\t4\t93318.000\t10857.340\t1.16e-01\t5.43e-04\n",
      "\t\t3\t161124.000\t121874.170\t7.56e-01\t6.09e-03\n",
      "\t\t2\t468950.000\t1039016.920\t1.00e+00\t5.20e-02\n",
      "\t\t1\t1538885.000\t6090207.872\t1.00e+00\t3.05e-01\n",
      "\t\t0\t1538885.000\t19999999.996\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 6.09e-03)\n",
      "\t\tFinding peaks on chr7 (minCount=0.6), total tags positions = 797954\n",
      "\t\tFinding peaks on chr13 (minCount=-0.1), total tags positions = 306521\n",
      "\t\tFinding peaks on chr16 (minCount=0.5), total tags positions = 207896\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t6\t49166.000\t60.118\t1.22e-03\t3.01e-06\n",
      "\t\t5\t59877.000\t959.112\t1.60e-02\t4.80e-05\n",
      "\t\t4\t83412.000\t12799.648\t1.53e-01\t6.40e-04\n",
      "\t\t3\t171046.000\t137559.793\t8.04e-01\t6.88e-03\n",
      "\t\t2\t553987.000\t1123479.750\t1.00e+00\t5.62e-02\n",
      "\t\t1\t1683540.000\t6317649.943\t1.00e+00\t3.16e-01\n",
      "\t\t0\t1683540.000\t19999999.995\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 6.88e-03)\n",
      "\t\tFinding peaks on chr17 (minCount=-0.3), total tags positions = 226454\n",
      "\t\tTags Used for cluster (less clonal tags) = 4211219.0 / 14360460.0\n",
      "\tExpected tags per peak = 0.421122 (tbp = 0.002106)\n",
      "\t\tFinding peaks on chr8 (minCount=1.3), total tags positions = 915384\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t6\t52215.000\t52.796\t1.01e-03\t2.64e-06\n",
      "\t\t5\t63495.000\t861.586\t1.36e-02\t4.31e-05\n",
      "\t\t4\t86420.000\t11760.425\t1.36e-01\t5.88e-04\n",
      "\t\t3\t167350.000\t129254.023\t7.72e-01\t6.46e-03\n",
      "\t\t2\t520262.000\t1079223.057\t1.00e+00\t5.40e-02\n",
      "\t\t1\t1616306.000\t6199735.518\t1.00e+00\t3.10e-01\n",
      "\t\t0\t1616306.000\t19999999.995\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 3.0 (poisson pvalue ~ 6.46e-03)\n",
      "\t\tFinding peaks on chr13 (minCount=-0.0), total tags positions = 303331\n",
      "\t\tFinding peaks on chr12 (minCount=1.4), total tags positions = 352262\n",
      "\t161124 peaks passed threshold\n",
      "\t\tFinding peaks on chr9 (minCount=0.6), total tags positions = 535610\n",
      "\t\tFinding peaks on chr14 (minCount=0.5), total tags positions = 283863\n",
      "\t\tFinding peaks on chr6 (minCount=0.8), total tags positions = 802379\n",
      "\t\tFinding peaks on chr6 (minCount=1.1), total tags positions = 874103\n",
      "\t\tFinding peaks on chr12 (minCount=0.4), total tags positions = 477188\n",
      "\t\tFinding peaks on chr14 (minCount=-0.1), total tags positions = 279927\n",
      "\t\tFinding peaks on chr3 (minCount=3.6), total tags positions = 1548526\n",
      "\t\tFinding peaks on chr18 (minCount=-0.3), total tags positions = 192982\n",
      "\t\tFinding peaks on chr17 (minCount=0.5), total tags positions = 204499\n",
      "\t\tFinding peaks on chr13 (minCount=1.4), total tags positions = 366645\n",
      "\t171046 peaks passed threshold\n",
      "\t167350 peaks passed threshold\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t7\t49622.000\t6.455\t1.30e-04\t3.23e-07\n",
      "\t\t6\t58472.000\t108.139\t1.85e-03\t5.41e-06\n",
      "\t\t5\t71341.000\t1556.901\t2.18e-02\t7.78e-05\n",
      "\t\t4\t97889.000\t18758.116\t1.92e-01\t9.38e-04\n",
      "\t\t3\t192687.000\t182142.779\t9.45e-01\t9.11e-03\n",
      "\t\t2\t618257.000\t1346067.060\t1.00e+00\t6.73e-02\n",
      "\t\t1\t1842291.000\t6873798.086\t1.00e+00\t3.44e-01\n",
      "\t\t0\t1842291.000\t19999999.994\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 9.38e-04)\n",
      "\t\tFinding peaks on chr19 (minCount=-0.3), total tags positions = 153103\n",
      "\t\tFinding peaks on chr14 (minCount=-0.0), total tags positions = 268779\n",
      "\t\tFinding peaks on chr15 (minCount=0.5), total tags positions = 267514\n",
      "\tTotal Peaks identified = 196175\n",
      "\t\tFinding peaks on chr18 (minCount=0.5), total tags positions = 197507\n",
      "\t\tFinding peaks on chr7 (minCount=1.1), total tags positions = 974094\n",
      "\t\tFinding peaks on chr13 (minCount=1.4), total tags positions = 395943\n",
      "\t\tFinding peaks on chr7 (minCount=0.7), total tags positions = 801641\n",
      "\t\tFinding peaks on chr9 (minCount=1.3), total tags positions = 912459\n",
      "\t\tFinding peaks on chr15 (minCount=-0.1), total tags positions = 268541\n",
      "\t\tFinding peaks on chrX (minCount=-0.3), total tags positions = 129211\n",
      "\t\tFinding peaks on chr14 (minCount=1.4), total tags positions = 313277\n",
      "\t\tFinding peaks on chr6 (minCount=1.4), total tags positions = 966095\n",
      "\t\tFinding peaks on chrY (minCount=-0.3), total tags positions = 3915\n",
      "\tCentering peaks of size 200 using a fragment length of 67\n",
      "\t\tFinding peaks on chr13 (minCount=0.4), total tags positions = 497800\n",
      "\t\tFinding peaks on chr8 (minCount=0.6), total tags positions = 692460\n",
      "\t\tFinding peaks on chr7 (minCount=1.2), total tags positions = 1014072\n",
      "\t\tFinding peaks on chr19 (minCount=0.5), total tags positions = 137236\n",
      "\t97889 peaks passed threshold\n",
      "\t\tFinding peaks on chr10 (minCount=0.6), total tags positions = 523953\n",
      "\tTotal Peaks identified = 88981\n",
      "\t\tFinding peaks on chr16 (minCount=0.5), total tags positions = 236588\n",
      "\t\tFinding peaks on chr15 (minCount=-0.0), total tags positions = 261439\n",
      "\t\tFinding peaks on chr16 (minCount=-0.1), total tags positions = 244351\n",
      "\tCentering peaks of size 200 using a fragment length of 53\n",
      "\t\tFinding peaks on chrX (minCount=0.5), total tags positions = 223295\n",
      "\t\tFinding peaks on chr14 (minCount=1.4), total tags positions = 344072\n",
      "\t\tFinding peaks on chr14 (minCount=0.4), total tags positions = 450053\n",
      "\t\tFinding peaks on chr15 (minCount=1.4), total tags positions = 318161\n",
      "\t\tFinding peaks on chrY (minCount=0.5), total tags positions = 444\n",
      "\t\tFinding peaks on chr17 (minCount=-0.1), total tags positions = 264487\n",
      "\t\tFinding peaks on chr17 (minCount=0.5), total tags positions = 256711\n",
      "\t\tFinding peaks on chr7 (minCount=0.8), total tags positions = 857110\n",
      "\t\tFinding peaks on chr10 (minCount=1.3), total tags positions = 872035\n",
      "\t\tFinding peaks on chr16 (minCount=-0.0), total tags positions = 237352\n",
      "\t\tFinding peaks on chr18 (minCount=-0.1), total tags positions = 234474\n",
      "\t\tFinding peaks on chr8 (minCount=1.2), total tags positions = 874829\n",
      "\t\tFinding peaks on chr15 (minCount=1.4), total tags positions = 307142\n",
      "\t\tFinding peaks on chr7 (minCount=1.1), total tags positions = 953258\n",
      "\t\tFinding peaks on chr15 (minCount=0.4), total tags positions = 449986\n",
      "\t\tFinding peaks on chr16 (minCount=1.4), total tags positions = 278847\n",
      "\t\tFinding peaks on chr19 (minCount=-0.1), total tags positions = 183793\n",
      "\t\tFinding peaks on chr18 (minCount=0.5), total tags positions = 240086\n",
      "\t\tFinding peaks on chr11 (minCount=0.6), total tags positions = 548777\n",
      "\t\tFinding peaks on chr8 (minCount=1.1), total tags positions = 851106\n",
      "\t\tFinding peaks on chr8 (minCount=0.7), total tags positions = 697220\n",
      "\t\tFinding peaks on chrX (minCount=-0.1), total tags positions = 164349\n",
      "\t\tFinding peaks on chrY (minCount=-0.1), total tags positions = 3634\n",
      "\t\tFinding peaks on chr17 (minCount=-0.0), total tags positions = 273298\n",
      "\t\tFinding peaks on chr9 (minCount=0.6), total tags positions = 701113\n",
      "\t\tFinding peaks on chr16 (minCount=0.4), total tags positions = 390665\n",
      "\t\tFinding peaks on chr16 (minCount=1.4), total tags positions = 303846\n",
      "\t\tFinding peaks on chr19 (minCount=0.5), total tags positions = 159677\n",
      "\t\tTags Used for cluster (less clonal tags) = 5526285.0 / 7272783.0\n",
      "\tExpected tags per peak = 0.552629 (tbp = 0.002763)\n",
      "\t\tFinding peaks on chr11 (minCount=1.3), total tags positions = 1007507\n",
      "\t\tFinding peaks on chr7 (minCount=1.4), total tags positions = 1058793\n",
      "\t\tFinding peaks on chr17 (minCount=1.4), total tags positions = 323509\n",
      "\t\tTags Used for cluster (less clonal tags) = 5445090.0 / 14924511.0\n",
      "\tExpected tags per peak = 0.544509 (tbp = 0.002723)\n",
      "\t\tFinding peaks on chr9 (minCount=1.2), total tags positions = 897520\n",
      "\t\tFinding peaks on chrX (minCount=0.5), total tags positions = 173487\n",
      "\t\tFinding peaks on chr8 (minCount=0.8), total tags positions = 752165\n",
      "\t\tFinding peaks on chr4 (minCount=3.6), total tags positions = 1755902\n",
      "\t\tFinding peaks on chr18 (minCount=-0.0), total tags positions = 237091\n",
      "\t\tFinding peaks on chr17 (minCount=0.4), total tags positions = 439389\n",
      "\t\tFinding peaks on chrY (minCount=0.5), total tags positions = 6874\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.5), total tags positions = 95\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.5), total tags positions = 194\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.5), total tags positions = 126\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.5), total tags positions = 117\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.5), total tags positions = 244\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.5), total tags positions = 44\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.5), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.5), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.5), total tags positions = 3\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.5), total tags positions = 5\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.5), total tags positions = 129\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.5), total tags positions = 337\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.5), total tags positions = 103\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.5), total tags positions = 74\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.5), total tags positions = 96\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.5), total tags positions = 39\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.5), total tags positions = 27\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.5), total tags positions = 29\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.5), total tags positions = 32\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.5), total tags positions = 65\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.5), total tags positions = 80\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.5), total tags positions = 22\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.5), total tags positions = 14\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.5), total tags positions = 112\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.5), total tags positions = 59\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.5), total tags positions = 92\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.5), total tags positions = 130\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.5), total tags positions = 76\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.5), total tags positions = 456\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.5), total tags positions = 200\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.5), total tags positions = 35\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.5), total tags positions = 69\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.5), total tags positions = 4299\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.5), total tags positions = 335\n",
      "\t\tFinding peaks on chr17 (minCount=1.4), total tags positions = 313082\n",
      "\t\tFinding peaks on chr12 (minCount=0.6), total tags positions = 459342\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t7\t54594.000\t38.589\t7.07e-04\t1.93e-06\n",
      "\t\t6\t63379.000\t493.884\t7.79e-03\t2.47e-05\n",
      "\t\t5\t78137.000\t5437.124\t6.96e-02\t2.72e-04\n",
      "\t\t4\t115281.000\t50161.923\t4.35e-01\t2.51e-03\n",
      "\t\t3\t254381.000\t373886.071\t1.00e+00\t1.87e-02\n",
      "\t\t2\t765152.000\t2131255.501\t1.00e+00\t1.07e-01\n",
      "\t\t1\t1945492.000\t8491294.403\t1.00e+00\t4.25e-01\n",
      "\t\t0\t1945492.000\t19999999.988\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 2.51e-03)\n",
      "\t\tFinding peaks on chr18 (minCount=1.4), total tags positions = 258945\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t7\t54775.000\t35.037\t6.40e-04\t1.75e-06\n",
      "\t\t6\t64796.000\t455.038\t7.02e-03\t2.28e-05\n",
      "\t\t5\t81465.000\t5083.074\t6.24e-02\t2.54e-04\n",
      "\t\t4\t124004.000\t47580.412\t3.84e-01\t2.38e-03\n",
      "\t\t3\t287039.000\t359768.736\t1.00e+00\t1.80e-02\n",
      "\t\t2\t882808.000\t2079786.224\t1.00e+00\t1.04e-01\n",
      "\t\t1\t2118117.000\t8397468.803\t1.00e+00\t4.20e-01\n",
      "\t\t0\t2118117.000\t19999999.989\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 2.38e-03)\n",
      "\t\tFinding peaks on chr19 (minCount=-0.0), total tags positions = 177157\n",
      "\t\tFinding peaks on chr18 (minCount=0.4), total tags positions = 376636\n",
      "\t\tFinding peaks on chr9 (minCount=1.1), total tags positions = 856084\n",
      "\t\tFinding peaks on chr12 (minCount=1.3), total tags positions = 755216\n",
      "\t\tTags Used for cluster (less clonal tags) = 6508023.0 / 9202597.0\n",
      "\tExpected tags per peak = 0.650802 (tbp = 0.003254)\n",
      "\t\tFinding peaks on chr9 (minCount=0.7), total tags positions = 705005\n",
      "\t\tFinding peaks on chr8 (minCount=1.1), total tags positions = 830410\n",
      "\t\tFinding peaks on chr19 (minCount=1.4), total tags positions = 219300\n",
      "\t\tFinding peaks on chr18 (minCount=1.4), total tags positions = 294333\n",
      "\t\tFinding peaks on chrX (minCount=-0.0), total tags positions = 152570\n",
      "\t\tFinding peaks on chr10 (minCount=0.6), total tags positions = 658984\n",
      "\t\tFinding peaks on chr19 (minCount=0.4), total tags positions = 288914\n",
      "\t115281 peaks passed threshold\n",
      "\t124004 peaks passed threshold\n",
      "\t\tFinding peaks on chrY (minCount=-0.0), total tags positions = 4938\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t8\t65788.000\t8.970\t1.36e-04\t4.49e-07\n",
      "\t\t7\t74077.000\t111.324\t1.50e-03\t5.57e-06\n",
      "\t\t6\t85531.000\t1212.235\t1.42e-02\t6.06e-05\n",
      "\t\t5\t104375.000\t11361.961\t1.09e-01\t5.68e-04\n",
      "\t\t4\t149648.000\t89340.526\t5.97e-01\t4.47e-03\n",
      "\t\t3\t304073.000\t568617.040\t1.00e+00\t2.84e-02\n",
      "\t\t2\t835890.000\t2777935.507\t1.00e+00\t1.39e-01\n",
      "\t\t1\t1994484.000\t9567457.984\t1.00e+00\t4.78e-01\n",
      "\t\t0\t1994484.000\t19999999.983\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 4.47e-03)\n",
      "\t\tFinding peaks on chrX (minCount=1.4), total tags positions = 185223\n",
      "\t\tFinding peaks on chr19 (minCount=1.4), total tags positions = 205356\n",
      "\t\tFinding peaks on chrX (minCount=0.4), total tags positions = 237776\n",
      "\t\tFinding peaks on chrY (minCount=1.4), total tags positions = 6256\n",
      "\t\tFinding peaks on chr13 (minCount=0.6), total tags positions = 476832\n",
      "\t\tFinding peaks on chr13 (minCount=1.3), total tags positions = 766995\n",
      "\tTotal Peaks identified = 119557\n",
      "\t\tFinding peaks on chr10 (minCount=1.1), total tags positions = 810545\n",
      "\t\tFinding peaks on chrY (minCount=0.4), total tags positions = 8023\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.4), total tags positions = 222\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.4), total tags positions = 376\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.4), total tags positions = 209\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.4), total tags positions = 196\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.4), total tags positions = 569\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.4), total tags positions = 67\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.4), total tags positions = 33\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.4), total tags positions = 22\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.4), total tags positions = 7\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.4), total tags positions = 8\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.4), total tags positions = 183\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.4), total tags positions = 597\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.4), total tags positions = 222\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.4), total tags positions = 104\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.4), total tags positions = 108\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.4), total tags positions = 44\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.4), total tags positions = 42\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.4), total tags positions = 111\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.4), total tags positions = 39\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.4), total tags positions = 120\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.4), total tags positions = 94\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.4), total tags positions = 109\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.4), total tags positions = 17\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.4), total tags positions = 148\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.4), total tags positions = 71\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.4), total tags positions = 279\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.4), total tags positions = 174\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.4), total tags positions = 93\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.4), total tags positions = 474\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.4), total tags positions = 481\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.4), total tags positions = 62\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.4), total tags positions = 95\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.4), total tags positions = 7001\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.4), total tags positions = 420\n",
      "\t\tFinding peaks on chrY_JH584301_random (minCount=0.4), total tags positions = 1\n",
      "\t\tFinding peaks on chr9 (minCount=0.8), total tags positions = 757215\n",
      "\t\tFinding peaks on chrX (minCount=1.4), total tags positions = 206369\n",
      "\t\tFinding peaks on chr8 (minCount=1.4), total tags positions = 926091\n",
      "\t\tFinding peaks on chrY (minCount=1.4), total tags positions = 5550\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=1.4), total tags positions = 112\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=1.4), total tags positions = 158\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=1.4), total tags positions = 113\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=1.4), total tags positions = 66\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=1.4), total tags positions = 533\n",
      "\t\tFinding peaks on chr10 (minCount=1.2), total tags positions = 841729\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=1.4), total tags positions = 49\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=1.4), total tags positions = 13\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=1.4), total tags positions = 17\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=1.4), total tags positions = 4\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=1.4), total tags positions = 5\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=1.4), total tags positions = 84\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=1.4), total tags positions = 248\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=1.4), total tags positions = 209\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=1.4), total tags positions = 47\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=1.4), total tags positions = 55\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=1.4), total tags positions = 51\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=1.4), total tags positions = 22\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=1.4), total tags positions = 18\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=1.4), total tags positions = 32\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=1.4), total tags positions = 60\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=1.4), total tags positions = 45\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=1.4), total tags positions = 28\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=1.4), total tags positions = 11\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=1.4), total tags positions = 47\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=1.4), total tags positions = 44\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=1.4), total tags positions = 95\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=1.4), total tags positions = 73\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=1.4), total tags positions = 31\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=1.4), total tags positions = 202\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=1.4), total tags positions = 145\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=1.4), total tags positions = 42\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=1.4), total tags positions = 32\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=1.4), total tags positions = 3861\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=1.4), total tags positions = 413\n",
      "\t149648 peaks passed threshold\n",
      "\tCentering peaks of size 200 using a fragment length of 237\n",
      "\t\tFinding peaks on chr10 (minCount=0.7), total tags positions = 661083\n",
      "\t\tFinding peaks on chr11 (minCount=0.6), total tags positions = 770898\n",
      "\t\tFinding peaks on chr14 (minCount=1.3), total tags positions = 720179\n",
      "\t\tFinding peaks on chr9 (minCount=1.1), total tags positions = 834610\n",
      "\t\tTags Used for cluster (less clonal tags) = 7816437.0 / 24132118.0\n",
      "\tExpected tags per peak = 0.781644 (tbp = 0.003908)\n",
      "\t\tFinding peaks on chr14 (minCount=0.6), total tags positions = 442200\n",
      "\t\tTags Used for cluster (less clonal tags) = 6518953.0 / 15183467.0\n",
      "\tExpected tags per peak = 0.651895 (tbp = 0.003259)\n",
      "\t\tFinding peaks on chr11 (minCount=1.1), total tags positions = 945532\n",
      "\t\tTags Used for cluster (less clonal tags) = 8034007.0 / 23688056.0\n",
      "\tExpected tags per peak = 0.803401 (tbp = 0.004017)\n",
      "\t\tFinding peaks on chr9 (minCount=1.4), total tags positions = 935794\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t8\t67147.000\t34.609\t5.15e-04\t1.73e-06\n",
      "\t\t7\t77422.000\t358.350\t4.63e-03\t1.79e-05\n",
      "\t\t6\t92537.000\t3257.608\t3.52e-02\t1.63e-04\n",
      "\t\t5\t120195.000\t25512.696\t2.12e-01\t1.28e-03\n",
      "\t\t4\t190051.000\t167873.524\t8.83e-01\t8.39e-03\n",
      "\t\t3\t408757.000\t896393.847\t1.00e+00\t4.48e-02\n",
      "\t\t2\t1030571.000\t3692502.925\t1.00e+00\t1.85e-01\n",
      "\t\t1\t1030571.000\t10846936.905\t1.00e+00\t5.42e-01\n",
      "\t\t0\t1030571.000\t19999999.974\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 8.39e-03)\n",
      "\t\tTags Used for cluster (less clonal tags) = 6492227.0 / 9775226.0\n",
      "\tExpected tags per peak = 0.649223 (tbp = 0.003246)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t8\t83427.000\t42.292\t5.07e-04\t2.11e-06\n",
      "\t\t7\t93785.000\t426.187\t4.54e-03\t2.13e-05\n",
      "\t\t6\t109119.000\t3771.049\t3.46e-02\t1.89e-04\n",
      "\t\t5\t139032.000\t28751.326\t2.07e-01\t1.44e-03\n",
      "\t\t4\t219585.000\t184217.198\t8.39e-01\t9.21e-03\n",
      "\t\t3\t470587.000\t958256.223\t1.00e+00\t4.79e-02\n",
      "\t\t2\t1139558.000\t3848616.080\t1.00e+00\t1.92e-01\n",
      "\t\t1\t1139558.000\t11043929.403\t1.00e+00\t5.52e-01\n",
      "\t\t0\t1139558.000\t19999999.972\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 9.21e-03)\n",
      "\t190051 peaks passed threshold\n",
      "\t\tFinding peaks on chr10 (minCount=0.8), total tags positions = 721961\n",
      "\t\tFinding peaks on chr15 (minCount=1.3), total tags positions = 719633\n",
      "\t\tFinding peaks on chr10 (minCount=1.1), total tags positions = 788379\n",
      "\t\tFinding peaks on chr15 (minCount=0.6), total tags positions = 417416\n",
      "\t219585 peaks passed threshold\n",
      "\t\tFinding peaks on chr12 (minCount=1.1), total tags positions = 703596\n",
      "\t\tTags Used for cluster (less clonal tags) = 10792682.0 / 14233363.0\n",
      "\tExpected tags per peak = 1.079268 (tbp = 0.005396)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t8\t46188.000\t8.810\t1.91e-04\t4.40e-07\n",
      "\t\t7\t53011.000\t109.596\t2.07e-03\t5.48e-06\n",
      "\t\t6\t63246.000\t1196.286\t1.89e-02\t5.98e-05\n",
      "\t\t5\t84700.000\t11239.282\t1.33e-01\t5.62e-04\n",
      "\t\t4\t149672.000\t88585.598\t5.92e-01\t4.43e-03\n",
      "\t\t3\t375453.000\t565132.823\t1.00e+00\t2.83e-02\n",
      "\t\t2\t1031257.000\t2767215.044\t1.00e+00\t1.38e-01\n",
      "\t\t1\t2169908.000\t9550965.276\t1.00e+00\t4.78e-01\n",
      "\t\t0\t2169908.000\t19999999.983\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 4.43e-03)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t8\t29309.000\t9.083\t3.10e-04\t4.54e-07\n",
      "\t\t7\t35385.000\t112.532\t3.18e-03\t5.63e-06\n",
      "\t\t6\t46025.000\t1223.369\t2.66e-02\t6.12e-05\n",
      "\t\t5\t72997.000\t11447.429\t1.57e-01\t5.72e-04\n",
      "\t\t4\t166116.000\t89865.395\t5.41e-01\t4.49e-03\n",
      "\t\t3\t478335.000\t571034.496\t1.00e+00\t2.86e-02\n",
      "\t\t2\t1254347.000\t2785358.426\t1.00e+00\t1.39e-01\n",
      "\t\t1\t2342450.000\t9578854.214\t1.00e+00\t4.79e-01\n",
      "\t\t0\t2342450.000\t19999999.983\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 4.0 (poisson pvalue ~ 4.49e-03)\n",
      "\t\tFinding peaks on chr12 (minCount=0.6), total tags positions = 578040\n",
      "\t\tFinding peaks on chr11 (minCount=0.7), total tags positions = 777928\n",
      "\t\tFinding peaks on chr10 (minCount=1.4), total tags positions = 878049\n",
      "\t\tFinding peaks on chr11 (minCount=1.2), total tags positions = 990377\n",
      "\t\tFinding peaks on chr16 (minCount=0.6), total tags positions = 379304\n",
      "\t\tFinding peaks on chr5 (minCount=3.6), total tags positions = 1783029\n",
      "\t\tFinding peaks on chr16 (minCount=1.3), total tags positions = 603710\n",
      "\t149672 peaks passed threshold\n",
      "\tTotal Peaks identified = 161124\n",
      "\t\tFinding peaks on chr17 (minCount=0.6), total tags positions = 395769\n",
      "\t\tFinding peaks on chr11 (minCount=1.1), total tags positions = 938648\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t10\t42758.000\t4.449\t1.04e-04\t2.22e-07\n",
      "\t\t9\t48850.000\t41.664\t8.53e-04\t2.08e-06\n",
      "\t\t8\t59048.000\t351.994\t5.96e-03\t1.76e-05\n",
      "\t\t7\t80180.000\t2652.296\t3.31e-02\t1.33e-04\n",
      "\t\t6\t131065.000\t17571.771\t1.34e-01\t8.79e-04\n",
      "\t\t5\t253521.000\t100513.949\t3.96e-01\t5.03e-03\n",
      "\t\t4\t524545.000\t484765.884\t9.24e-01\t2.42e-02\n",
      "\t\t3\t1028395.000\t1908886.155\t1.00e+00\t9.54e-02\n",
      "\t\t2\t1755910.000\t5867458.113\t1.00e+00\t2.93e-01\n",
      "\t\t1\t2505337.000\t13203117.409\t1.00e+00\t6.60e-01\n",
      "\t\t0\t2505337.000\t19999999.945\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 5.03e-03)\n",
      "\t\tFinding peaks on chr13 (minCount=0.6), total tags positions = 586097\n",
      "\t\tFinding peaks on chr12 (minCount=0.7), total tags positions = 575294\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\t166116 peaks passed threshold\n",
      "\t\tFinding peaks on chr13 (minCount=1.1), total tags positions = 722767\n",
      "\t\tFinding peaks on chr18 (minCount=0.6), total tags positions = 361491\n",
      "\t\tFinding peaks on chr17 (minCount=1.3), total tags positions = 700823\n",
      "\t\tFinding peaks on chr11 (minCount=1.4), total tags positions = 1015811\n",
      "\t\tFinding peaks on chr11 (minCount=0.8), total tags positions = 827482\n",
      "\t253521 peaks passed threshold\n",
      "\t\tFinding peaks on chr14 (minCount=0.6), total tags positions = 551352\n",
      "\tTotal Peaks identified = 171046\n",
      "\t\tFinding peaks on chr19 (minCount=0.6), total tags positions = 268822\n",
      "\t\tFinding peaks on chr13 (minCount=0.7), total tags positions = 592217\n",
      "\t\tFinding peaks on chr12 (minCount=1.1), total tags positions = 686337\n",
      "\t\tFinding peaks on chr12 (minCount=1.2), total tags positions = 733993\n",
      "\tTotal Peaks identified = 97889\n",
      "\t\tFinding peaks on chrX (minCount=0.6), total tags positions = 236052\n",
      "\t\tFinding peaks on chr18 (minCount=1.3), total tags positions = 583406\n",
      "\t\tFinding peaks on chr14 (minCount=1.1), total tags positions = 675032\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\t\tFinding peaks on chrY (minCount=0.6), total tags positions = 10085\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.6), total tags positions = 183\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.6), total tags positions = 329\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.6), total tags positions = 205\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.6), total tags positions = 181\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.6), total tags positions = 319\n",
      "\t\tFinding peaks on chr4_GL456350_random (minCount=0.6), total tags positions = 1\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.6), total tags positions = 54\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.6), total tags positions = 14\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.6), total tags positions = 13\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.6), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.6), total tags positions = 6\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.6), total tags positions = 144\n",
      "\t\tFinding peaks on chr7_GL456219_random (minCount=0.6), total tags positions = 1\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.6), total tags positions = 479\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.6), total tags positions = 137\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.6), total tags positions = 92\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.6), total tags positions = 103\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.6), total tags positions = 61\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.6), total tags positions = 43\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.6), total tags positions = 29\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.6), total tags positions = 42\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.6), total tags positions = 108\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.6), total tags positions = 79\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.6), total tags positions = 38\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.6), total tags positions = 11\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.6), total tags positions = 229\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.6), total tags positions = 81\n",
      "\tCentering peaks of size 200 using a fragment length of 88\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.6), total tags positions = 129\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.6), total tags positions = 166\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.6), total tags positions = 113\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.6), total tags positions = 581\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.6), total tags positions = 266\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.6), total tags positions = 51\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.6), total tags positions = 87\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.6), total tags positions = 6083\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.6), total tags positions = 503\n",
      "\t\tFinding peaks on chr15 (minCount=0.6), total tags positions = 543688\n",
      "\t\tFinding peaks on chr14 (minCount=0.7), total tags positions = 547703\n",
      "\t\tFinding peaks on chr12 (minCount=1.4), total tags positions = 765723\n",
      "\t\tFinding peaks on chr12 (minCount=0.8), total tags positions = 624127\n",
      "\t\tFinding peaks on chr19 (minCount=1.3), total tags positions = 439390\n",
      "\t\tFinding peaks on chr13 (minCount=1.1), total tags positions = 706012\n",
      "\t\tFinding peaks on chr13 (minCount=1.2), total tags positions = 761970\n",
      "\t\tFinding peaks on chr15 (minCount=1.1), total tags positions = 659271\n",
      "\t\tFinding peaks on chr6 (minCount=3.6), total tags positions = 1583034\n",
      "\tTotal Peaks identified = 167350\n",
      "\t\tFinding peaks on chr16 (minCount=0.6), total tags positions = 459705\n",
      "\t\tFinding peaks on chrX (minCount=1.3), total tags positions = 363808\n",
      "\t\tFinding peaks on chr15 (minCount=0.7), total tags positions = 541356\n",
      "\t\tFinding peaks on chrY (minCount=1.3), total tags positions = 13233\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=1.3), total tags positions = 377\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=1.3), total tags positions = 549\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=1.3), total tags positions = 370\n",
      "\tCentering peaks of size 200 using a fragment length of 76\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=1.3), total tags positions = 359\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=1.3), total tags positions = 690\n",
      "\t\tFinding peaks on chr4_GL456350_random (minCount=1.3), total tags positions = 1\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=1.3), total tags positions = 103\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=1.3), total tags positions = 48\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=1.3), total tags positions = 29\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=1.3), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=1.3), total tags positions = 30\n",
      "\t\tFinding peaks on chr5_JH584298_random (minCount=1.3), total tags positions = 1\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=1.3), total tags positions = 309\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=1.3), total tags positions = 1072\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=1.3), total tags positions = 258\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=1.3), total tags positions = 156\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=1.3), total tags positions = 164\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=1.3), total tags positions = 93\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=1.3), total tags positions = 73\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=1.3), total tags positions = 186\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=1.3), total tags positions = 68\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=1.3), total tags positions = 195\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=1.3), total tags positions = 126\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=1.3), total tags positions = 144\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=1.3), total tags positions = 26\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=1.3), total tags positions = 175\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=1.3), total tags positions = 90\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=1.3), total tags positions = 424\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=1.3), total tags positions = 210\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=1.3), total tags positions = 117\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=1.3), total tags positions = 509\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=1.3), total tags positions = 686\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=1.3), total tags positions = 115\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=1.3), total tags positions = 129\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=1.3), total tags positions = 9040\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=1.3), total tags positions = 706\n",
      "\t\tFinding peaks on chr13 (minCount=0.8), total tags positions = 645960\n",
      "\t\tFinding peaks on chr13 (minCount=1.4), total tags positions = 784022\n",
      "\t\tFinding peaks on chr14 (minCount=1.1), total tags positions = 653534\n",
      "\t\tFinding peaks on chr16 (minCount=1.1), total tags positions = 565234\n",
      "\t\tFinding peaks on chr17 (minCount=0.6), total tags positions = 532557\n",
      "\t\tFinding peaks on chr14 (minCount=1.2), total tags positions = 705319\n",
      "\t\tFinding peaks on chr16 (minCount=0.7), total tags positions = 462242\n",
      "\t\tTags Used for cluster (less clonal tags) = 10041511.0 / 15990733.0\n",
      "\tExpected tags per peak = 1.004151 (tbp = 0.005021)\n",
      "\t\tFinding peaks on chr14 (minCount=0.8), total tags positions = 599557\n",
      "\t\tFinding peaks on chr18 (minCount=0.6), total tags positions = 441131\n",
      "\t\tFinding peaks on chr15 (minCount=1.1), total tags positions = 648011\n",
      "\t\tFinding peaks on chr17 (minCount=1.1), total tags positions = 649089\n",
      "\t\tFinding peaks on chr17 (minCount=0.7), total tags positions = 529784\n",
      "\t\tFinding peaks on chr14 (minCount=1.4), total tags positions = 733199\n",
      "\t\tFinding peaks on chr15 (minCount=1.2), total tags positions = 692091\n",
      "\t\tTags Used for cluster (less clonal tags) = 17041645.0 / 23448604.0\n",
      "\tExpected tags per peak = 1.704164 (tbp = 0.008521)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t9\t31987.000\t23.273\t7.28e-04\t1.16e-06\n",
      "\t\t8\t38655.000\t211.120\t5.46e-03\t1.06e-05\n",
      "\t\t7\t49946.000\t1707.685\t3.42e-02\t8.54e-05\n",
      "\t\t6\t77376.000\t12140.334\t1.57e-01\t6.07e-04\n",
      "\t\t5\t160577.000\t74477.463\t4.64e-01\t3.72e-03\n",
      "\t\t4\t403506.000\t384874.625\t9.54e-01\t1.92e-02\n",
      "\t\t3\t973117.000\t1621330.619\t1.00e+00\t8.11e-02\n",
      "\t\t2\t1858279.000\t5315364.349\t1.00e+00\t2.66e-01\n",
      "\t\t1\t2622232.000\t12672889.956\t1.00e+00\t6.34e-01\n",
      "\t\t0\t2622232.000\t19999999.953\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 3.72e-03)\n",
      "\t\tFinding peaks on chr19 (minCount=0.6), total tags positions = 339410\n",
      "\t\tFinding peaks on chr15 (minCount=0.8), total tags positions = 594723\n",
      "\t\tFinding peaks on chr16 (minCount=1.1), total tags positions = 548735\n",
      "\t\tFinding peaks on chr18 (minCount=0.7), total tags positions = 447556\n",
      "\t\tFinding peaks on chrX (minCount=0.6), total tags positions = 273174\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t12\t42790.000\t5.237\t1.22e-04\t2.62e-07\n",
      "\t\t11\t51345.000\t37.328\t7.27e-04\t1.87e-06\n",
      "\t\t10\t65916.000\t244.472\t3.71e-03\t1.22e-05\n",
      "\t\t9\t93219.000\t1459.990\t1.57e-02\t7.30e-05\n",
      "\t\t8\t145620.000\t7879.357\t5.41e-02\t3.94e-04\n",
      "\t\t7\t245056.000\t38014.308\t1.55e-01\t1.90e-03\n",
      "\t\t6\t424673.000\t161796.220\t3.81e-01\t8.09e-03\n",
      "\t\t5\t721042.000\t597605.990\t8.29e-01\t2.99e-02\n",
      "\t\t4\t1151630.000\t1876267.210\t1.00e+00\t9.38e-02\n",
      "\t\t3\t1685659.000\t4877529.849\t1.00e+00\t2.44e-01\n",
      "\t\t2\t2233656.000\t10160933.357\t1.00e+00\t5.08e-01\n",
      "\t\t1\t2233656.000\t16361513.022\t1.00e+00\t8.18e-01\n",
      "\t\t0\t2233656.000\t19999999.847\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 2.99e-02)\n",
      "\tTotal Peaks identified = 124004\n",
      "\t\tFinding peaks on chrY (minCount=0.6), total tags positions = 9577\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.6), total tags positions = 270\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.6), total tags positions = 473\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.6), total tags positions = 298\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.6), total tags positions = 223\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.6), total tags positions = 521\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.6), total tags positions = 85\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.6), total tags positions = 19\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.6), total tags positions = 32\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.6), total tags positions = 4\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.6), total tags positions = 12\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.6), total tags positions = 236\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.6), total tags positions = 815\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.6), total tags positions = 201\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.6), total tags positions = 120\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.6), total tags positions = 134\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.6), total tags positions = 67\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.6), total tags positions = 46\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.6), total tags positions = 124\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.6), total tags positions = 70\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.6), total tags positions = 129\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.6), total tags positions = 102\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.6), total tags positions = 146\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.6), total tags positions = 16\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.6), total tags positions = 118\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.6), total tags positions = 69\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.6), total tags positions = 345\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.6), total tags positions = 140\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.6), total tags positions = 70\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.6), total tags positions = 370\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.6), total tags positions = 575\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.6), total tags positions = 83\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.6), total tags positions = 80\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.6), total tags positions = 7333\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.6), total tags positions = 444\n",
      "\t160577 peaks passed threshold\n",
      "\t\tFinding peaks on chr7 (minCount=3.6), total tags positions = 1702535\n",
      "\tCentering peaks of size 200 using a fragment length of 67\n",
      "\t\tFinding peaks on chr15 (minCount=1.4), total tags positions = 719539\n",
      "\t\tFinding peaks on chr19 (minCount=0.7), total tags positions = 340484\n",
      "\t\tFinding peaks on chr16 (minCount=1.2), total tags positions = 592350\n",
      "\t\tFinding peaks on chr18 (minCount=1.1), total tags positions = 540072\n",
      "\tTotal Peaks identified = 115281\n",
      "\t\tFinding peaks on chr16 (minCount=0.8), total tags positions = 511988\n",
      "\t\tFinding peaks on chr17 (minCount=1.1), total tags positions = 645754\n",
      "\t\tFinding peaks on chrX (minCount=0.7), total tags positions = 279573\n",
      "\tCentering peaks of size 200 using a fragment length of 71\n",
      "\t\tFinding peaks on chrY (minCount=0.7), total tags positions = 9608\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.7), total tags positions = 276\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.7), total tags positions = 419\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.7), total tags positions = 323\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.7), total tags positions = 267\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.7), total tags positions = 531\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.7), total tags positions = 78\n",
      "\t\tFinding peaks on chr4_JH584293_random (minCount=0.7), total tags positions = 1\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.7), total tags positions = 41\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.7), total tags positions = 22\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.7), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.7), total tags positions = 5\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.7), total tags positions = 240\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.7), total tags positions = 744\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.7), total tags positions = 188\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.7), total tags positions = 109\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.7), total tags positions = 124\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.7), total tags positions = 56\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.7), total tags positions = 54\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.7), total tags positions = 129\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.7), total tags positions = 65\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.7), total tags positions = 144\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.7), total tags positions = 109\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.7), total tags positions = 121\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.7), total tags positions = 23\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.7), total tags positions = 135\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.7), total tags positions = 64\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.7), total tags positions = 306\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.7), total tags positions = 144\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.7), total tags positions = 83\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.7), total tags positions = 380\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.7), total tags positions = 531\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.7), total tags positions = 91\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.7), total tags positions = 75\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.7), total tags positions = 7160\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.7), total tags positions = 528\n",
      "\t\tFinding peaks on chr19 (minCount=1.1), total tags positions = 415967\n",
      "\t721042 peaks passed threshold\n",
      "\t\tFinding peaks on chr16 (minCount=1.4), total tags positions = 613361\n",
      "\t\tFinding peaks on chr17 (minCount=1.2), total tags positions = 676129\n",
      "\t\tFinding peaks on chr17 (minCount=0.8), total tags positions = 569359\n",
      "\t\tFinding peaks on chr18 (minCount=1.1), total tags positions = 534444\n",
      "\t\tFinding peaks on chrX (minCount=1.1), total tags positions = 337828\n",
      "\t\tFinding peaks on chrY (minCount=1.1), total tags positions = 12147\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=1.1), total tags positions = 332\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=1.1), total tags positions = 501\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=1.1), total tags positions = 349\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=1.1), total tags positions = 291\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=1.1), total tags positions = 736\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=1.1), total tags positions = 89\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=1.1), total tags positions = 35\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=1.1), total tags positions = 34\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=1.1), total tags positions = 7\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=1.1), total tags positions = 15\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=1.1), total tags positions = 276\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=1.1), total tags positions = 922\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=1.1), total tags positions = 240\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=1.1), total tags positions = 151\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=1.1), total tags positions = 164\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=1.1), total tags positions = 76\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=1.1), total tags positions = 68\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=1.1), total tags positions = 175\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=1.1), total tags positions = 56\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=1.1), total tags positions = 155\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=1.1), total tags positions = 115\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=1.1), total tags positions = 142\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=1.1), total tags positions = 16\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=1.1), total tags positions = 154\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=1.1), total tags positions = 77\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=1.1), total tags positions = 396\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=1.1), total tags positions = 196\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=1.1), total tags positions = 102\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=1.1), total tags positions = 464\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=1.1), total tags positions = 736\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=1.1), total tags positions = 133\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=1.1), total tags positions = 108\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=1.1), total tags positions = 8553\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=1.1), total tags positions = 612\n",
      "\t\tFinding peaks on chr18 (minCount=0.8), total tags positions = 487248\n",
      "\t\tFinding peaks on chr19 (minCount=1.1), total tags positions = 414757\n",
      "\t\tFinding peaks on chr17 (minCount=1.4), total tags positions = 702830\n",
      "\t\tFinding peaks on chr18 (minCount=1.2), total tags positions = 570330\n",
      "\t\tTags Used for cluster (less clonal tags) = 12962984.0 / 15576423.0\n",
      "\tExpected tags per peak = 1.296298 (tbp = 0.006481)\n",
      "\t\tFinding peaks on chrX (minCount=1.1), total tags positions = 327232\n",
      "\t\tFinding peaks on chr8 (minCount=3.6), total tags positions = 1501346\n",
      "\t\tFinding peaks on chr19 (minCount=0.8), total tags positions = 363464\n",
      "\t\tFinding peaks on chrY (minCount=1.1), total tags positions = 10303\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=1.1), total tags positions = 287\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=1.1), total tags positions = 408\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=1.1), total tags positions = 306\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=1.1), total tags positions = 262\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=1.1), total tags positions = 592\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=1.1), total tags positions = 93\n",
      "\t\tFinding peaks on chr4_JH584293_random (minCount=1.1), total tags positions = 1\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=1.1), total tags positions = 49\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=1.1), total tags positions = 23\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=1.1), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=1.1), total tags positions = 9\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=1.1), total tags positions = 229\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=1.1), total tags positions = 849\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=1.1), total tags positions = 235\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=1.1), total tags positions = 136\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=1.1), total tags positions = 158\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=1.1), total tags positions = 53\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=1.1), total tags positions = 53\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=1.1), total tags positions = 145\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=1.1), total tags positions = 65\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=1.1), total tags positions = 153\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=1.1), total tags positions = 93\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=1.1), total tags positions = 120\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=1.1), total tags positions = 24\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=1.1), total tags positions = 108\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=1.1), total tags positions = 67\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=1.1), total tags positions = 343\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=1.1), total tags positions = 152\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=1.1), total tags positions = 78\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=1.1), total tags positions = 358\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=1.1), total tags positions = 590\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=1.1), total tags positions = 86\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=1.1), total tags positions = 64\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=1.1), total tags positions = 7448\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=1.1), total tags positions = 627\n",
      "\t\tFinding peaks on chr19 (minCount=1.2), total tags positions = 434928\n",
      "\tTotal Peaks identified = 149648\n",
      "\t\tTags Used for cluster (less clonal tags) = 13020249.0 / 16739327.0\n",
      "\tExpected tags per peak = 1.302025 (tbp = 0.006510)\n",
      "\t\tFinding peaks on chr18 (minCount=1.4), total tags positions = 595212\n",
      "\t\tFinding peaks on chrX (minCount=0.8), total tags positions = 308720\n",
      "\tCentering peaks of size 200 using a fragment length of 60\n",
      "\t\tFinding peaks on chrY (minCount=0.8), total tags positions = 11200\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=0.8), total tags positions = 271\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=0.8), total tags positions = 485\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=0.8), total tags positions = 282\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=0.8), total tags positions = 295\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=0.8), total tags positions = 529\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=0.8), total tags positions = 113\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=0.8), total tags positions = 37\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=0.8), total tags positions = 26\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=0.8), total tags positions = 5\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=0.8), total tags positions = 5\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=0.8), total tags positions = 253\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=0.8), total tags positions = 863\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=0.8), total tags positions = 211\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=0.8), total tags positions = 135\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=0.8), total tags positions = 158\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=0.8), total tags positions = 72\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=0.8), total tags positions = 63\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=0.8), total tags positions = 159\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=0.8), total tags positions = 77\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=0.8), total tags positions = 141\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=0.8), total tags positions = 112\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=0.8), total tags positions = 136\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=0.8), total tags positions = 29\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=0.8), total tags positions = 204\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=0.8), total tags positions = 85\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=0.8), total tags positions = 327\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=0.8), total tags positions = 195\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=0.8), total tags positions = 96\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=0.8), total tags positions = 520\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=0.8), total tags positions = 602\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=0.8), total tags positions = 104\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=0.8), total tags positions = 125\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=0.8), total tags positions = 8143\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=0.8), total tags positions = 536\n",
      "\t\tFinding peaks on chrX (minCount=1.2), total tags positions = 350306\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t10\t36547.000\t22.865\t6.26e-04\t1.14e-06\n",
      "\t\t9\t48599.000\t178.690\t3.68e-03\t8.93e-06\n",
      "\t\t8\t73091.000\t1260.558\t1.72e-02\t6.30e-05\n",
      "\t\t7\t125149.000\t7937.212\t6.34e-02\t3.97e-04\n",
      "\t\t6\t233540.000\t43991.101\t1.88e-01\t2.20e-03\n",
      "\t\t5\t442609.000\t210868.833\t4.76e-01\t1.05e-02\n",
      "\t\t4\t805792.000\t854539.068\t1.00e+00\t4.27e-02\n",
      "\t\t3\t1341982.000\t2840718.317\t1.00e+00\t1.42e-01\n",
      "\t\t2\t1987021.000\t7437297.263\t1.00e+00\t3.72e-01\n",
      "\t\t1\t2584974.000\t14529150.511\t1.00e+00\t7.26e-01\n",
      "\t\t0\t2584974.000\t19999999.917\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 1.05e-02)\n",
      "\t\tFinding peaks on chrY (minCount=1.2), total tags positions = 12098\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=1.2), total tags positions = 332\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=1.2), total tags positions = 568\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=1.2), total tags positions = 360\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=1.2), total tags positions = 272\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=1.2), total tags positions = 631\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=1.2), total tags positions = 102\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=1.2), total tags positions = 30\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=1.2), total tags positions = 29\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=1.2), total tags positions = 6\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=1.2), total tags positions = 11\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=1.2), total tags positions = 261\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=1.2), total tags positions = 935\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=1.2), total tags positions = 254\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=1.2), total tags positions = 111\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=1.2), total tags positions = 149\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=1.2), total tags positions = 76\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=1.2), total tags positions = 62\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=1.2), total tags positions = 177\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=1.2), total tags positions = 84\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=1.2), total tags positions = 154\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=1.2), total tags positions = 117\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=1.2), total tags positions = 141\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=1.2), total tags positions = 33\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=1.2), total tags positions = 164\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=1.2), total tags positions = 94\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=1.2), total tags positions = 412\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=1.2), total tags positions = 175\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=1.2), total tags positions = 94\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=1.2), total tags positions = 424\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=1.2), total tags positions = 646\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=1.2), total tags positions = 116\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=1.2), total tags positions = 110\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=1.2), total tags positions = 8397\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=1.2), total tags positions = 632\n",
      "\t\tFinding peaks on chr19 (minCount=1.4), total tags positions = 447545\n",
      "\t\tTags Used for cluster (less clonal tags) = 15836921.0 / 21472882.0\n",
      "\tExpected tags per peak = 1.583692 (tbp = 0.007918)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t10\t41221.000\t23.773\t5.77e-04\t1.19e-06\n",
      "\t\t9\t52484.000\t184.978\t3.52e-03\t9.25e-06\n",
      "\t\t8\t75343.000\t1299.277\t1.72e-02\t6.50e-05\n",
      "\t\t7\t124097.000\t8145.834\t6.56e-02\t4.07e-04\n",
      "\t\t6\t226349.000\t44954.584\t1.99e-01\t2.25e-03\n",
      "\t\t5\t429885.000\t214576.912\t4.99e-01\t1.07e-02\n",
      "\t\t4\t789624.000\t865955.873\t1.00e+00\t4.33e-02\n",
      "\t\t3\t1331045.000\t2867081.760\t1.00e+00\t1.43e-01\n",
      "\t\t2\t1987636.000\t7477882.598\t1.00e+00\t3.74e-01\n",
      "\t\t1\t2589474.000\t14560390.210\t1.00e+00\t7.28e-01\n",
      "\t\t0\t2589474.000\t19999999.916\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 1.07e-02)\n",
      "\t\tFinding peaks on chrX (minCount=1.4), total tags positions = 371000\n",
      "\tTotal Peaks identified = 190051\n",
      "\t442609 peaks passed threshold\n",
      "\t\tFinding peaks on chrY (minCount=1.4), total tags positions = 13319\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=1.4), total tags positions = 347\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=1.4), total tags positions = 551\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=1.4), total tags positions = 397\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=1.4), total tags positions = 383\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=1.4), total tags positions = 668\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=1.4), total tags positions = 116\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=1.4), total tags positions = 48\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=1.4), total tags positions = 33\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=1.4), total tags positions = 11\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=1.4), total tags positions = 20\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=1.4), total tags positions = 310\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=1.4), total tags positions = 1092\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=1.4), total tags positions = 238\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=1.4), total tags positions = 132\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=1.4), total tags positions = 181\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=1.4), total tags positions = 72\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=1.4), total tags positions = 72\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=1.4), total tags positions = 189\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=1.4), total tags positions = 75\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=1.4), total tags positions = 189\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=1.4), total tags positions = 121\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=1.4), total tags positions = 159\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=1.4), total tags positions = 35\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=1.4), total tags positions = 169\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=1.4), total tags positions = 106\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=1.4), total tags positions = 449\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=1.4), total tags positions = 217\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=1.4), total tags positions = 95\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=1.4), total tags positions = 508\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=1.4), total tags positions = 740\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=1.4), total tags positions = 106\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=1.4), total tags positions = 122\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=1.4), total tags positions = 9075\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=1.4), total tags positions = 742\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t11\t45384.000\t18.586\t4.10e-04\t9.29e-07\n",
      "\t\t10\t57060.000\t130.836\t2.29e-03\t6.54e-06\n",
      "\t\t9\t79068.000\t839.622\t1.06e-02\t4.20e-05\n",
      "\t\t8\t122226.000\t4867.596\t3.98e-02\t2.43e-04\n",
      "\t\t7\t207090.000\t25214.849\t1.22e-01\t1.26e-03\n",
      "\t\t6\t365372.000\t115150.771\t3.15e-01\t5.76e-03\n",
      "\t\t5\t635441.000\t455883.391\t7.17e-01\t2.28e-02\n",
      "\t\t4\t1044926.000\t1531637.434\t1.00e+00\t7.66e-02\n",
      "\t\t3\t1574548.000\t4248716.250\t1.00e+00\t2.12e-01\n",
      "\t\t2\t2148446.000\t9395699.522\t1.00e+00\t4.70e-01\n",
      "\t\t1\t2148446.000\t15895679.369\t1.00e+00\t7.95e-01\n",
      "\t\t0\t2148446.000\t19999999.870\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 2.28e-02)\n",
      "\t\tTags Used for cluster (less clonal tags) = 15523823.0 / 21056721.0\n",
      "\tExpected tags per peak = 1.552382 (tbp = 0.007762)\n",
      "\t\tFinding peaks on chr9 (minCount=3.6), total tags positions = 1500642\n",
      "\tCentering peaks of size 200 using a fragment length of 525\n",
      "\t429885 peaks passed threshold\n",
      "\tTotal Peaks identified = 149672\n",
      "\tTotal Peaks identified = 219585\n",
      "\t\tTags Used for cluster (less clonal tags) = 14103257.0 / 18428481.0\n",
      "\tExpected tags per peak = 1.410326 (tbp = 0.007052)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t11\t43570.000\t15.351\t3.52e-04\t7.68e-07\n",
      "\t\t10\t54630.000\t110.206\t2.02e-03\t5.51e-06\n",
      "\t\t9\t75868.000\t721.238\t9.51e-03\t3.61e-05\n",
      "\t\t8\t117447.000\t4263.723\t3.63e-02\t2.13e-04\n",
      "\t\t7\t198898.000\t22519.448\t1.13e-01\t1.13e-03\n",
      "\t\t6\t351141.000\t104838.158\t2.99e-01\t5.24e-03\n",
      "\t\t5\t612148.000\t423002.217\t6.91e-01\t2.12e-02\n",
      "\t\t4\t1012469.000\t1447762.865\t1.00e+00\t7.24e-02\n",
      "\t\t3\t1538529.000\t4088248.058\t1.00e+00\t2.04e-01\n",
      "\t\t2\t2118443.000\t9191021.699\t1.00e+00\t4.60e-01\n",
      "\t\t1\t2118443.000\t15765141.342\t1.00e+00\t7.88e-01\n",
      "\t\t0\t2118443.000\t19999999.876\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 2.12e-02)\n",
      "\t\tTags Used for cluster (less clonal tags) = 16592136.0 / 22257432.0\n",
      "\tExpected tags per peak = 1.659214 (tbp = 0.008296)\n",
      "\tCentering peaks of size 200 using a fragment length of 66\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\t635441 peaks passed threshold\n",
      "\t\tTags Used for cluster (less clonal tags) = 17264700.0 / 23549529.0\n",
      "\tExpected tags per peak = 1.726470 (tbp = 0.008632)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t11\t34437.000\t6.076\t1.76e-04\t3.04e-07\n",
      "\t\t10\t40993.000\t47.952\t1.17e-03\t2.40e-06\n",
      "\t\t9\t52751.000\t344.876\t6.54e-03\t1.72e-05\n",
      "\t\t8\t77353.000\t2239.698\t2.90e-02\t1.12e-04\n",
      "\t\t7\t132461.000\t12987.970\t9.81e-02\t6.49e-04\n",
      "\t\t6\t251045.000\t66335.880\t2.64e-01\t3.32e-03\n",
      "\t\t5\t485638.000\t293295.831\t6.04e-01\t1.47e-02\n",
      "\t\t4\t890126.000\t1097932.474\t1.00e+00\t5.49e-02\n",
      "\t\t3\t1465268.000\t3380062.362\t1.00e+00\t1.69e-01\n",
      "\t\t2\t2108814.000\t8234536.390\t1.00e+00\t4.12e-01\n",
      "\t\t1\t2644778.000\t15118724.647\t1.00e+00\t7.56e-01\n",
      "\t\t0\t2644778.000\t19999999.900\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 1.47e-02)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t12\t41539.000\t3.959\t9.53e-05\t1.98e-07\n",
      "\t\t11\t49180.000\t28.975\t5.89e-04\t1.45e-06\n",
      "\t\t10\t62068.000\t194.820\t3.14e-03\t9.74e-06\n",
      "\t\t9\t86117.000\t1194.360\t1.39e-02\t5.97e-05\n",
      "\t\t8\t133303.000\t6616.122\t4.96e-02\t3.31e-04\n",
      "\t\t7\t225679.000\t32757.471\t1.45e-01\t1.64e-03\n",
      "\t\t6\t396143.000\t143044.360\t3.61e-01\t7.15e-03\n",
      "\t\t5\t682952.000\t541860.622\t7.93e-01\t2.71e-02\n",
      "\t\t4\t1106238.000\t1743683.847\t1.00e+00\t8.72e-02\n",
      "\t\t3\t1640364.000\t4641016.103\t1.00e+00\t2.32e-01\n",
      "\t\t2\t2197290.000\t9879640.739\t1.00e+00\t4.94e-01\n",
      "\t\t1\t2197290.000\t16194228.355\t1.00e+00\t8.10e-01\n",
      "\t\t0\t2197290.000\t19999999.856\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 2.71e-02)\n",
      "\t612148 peaks passed threshold\n",
      "\t\tFinding peaks on chr10 (minCount=3.6), total tags positions = 1440002\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t12\t40092.000\t5.998\t1.50e-04\t3.00e-07\n",
      "\t\t11\t48517.000\t42.208\t8.70e-04\t2.11e-06\n",
      "\t\t10\t63343.000\t272.915\t4.31e-03\t1.36e-05\n",
      "\t\t9\t91468.000\t1609.208\t1.76e-02\t8.05e-05\n",
      "\t\t8\t146609.000\t8575.239\t5.85e-02\t4.29e-04\n",
      "\t\t7\t251088.000\t40853.947\t1.63e-01\t2.04e-03\n",
      "\t\t6\t438375.000\t171728.522\t3.92e-01\t8.59e-03\n",
      "\t\t5\t740969.000\t626556.851\t8.46e-01\t3.13e-02\n",
      "\t\t4\t1173811.000\t1943777.378\t1.00e+00\t9.72e-02\n",
      "\t\t3\t1702578.000\t4995601.127\t1.00e+00\t2.50e-01\n",
      "\t\t2\t2239216.000\t10298601.736\t1.00e+00\t5.15e-01\n",
      "\t\t1\t2239216.000\t16441773.224\t1.00e+00\t8.22e-01\n",
      "\t\t0\t2239216.000\t19999999.843\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 5.0 (poisson pvalue ~ 3.13e-02)\n",
      "\tTotal Peaks identified = 166116\n",
      "\t485638 peaks passed threshold\n",
      "\t682952 peaks passed threshold\n",
      "\tCentering peaks of size 200 using a fragment length of 67\n",
      "\t740969 peaks passed threshold\n",
      "\t\tFinding peaks on chr11 (minCount=3.6), total tags positions = 1670835\n",
      "\t\tFinding peaks on chr12 (minCount=3.6), total tags positions = 1244183\n",
      "\t\tFinding peaks on chr13 (minCount=3.6), total tags positions = 1268389\n",
      "\tTotal Peaks identified = 253521\n",
      "\tTotal Peaks identified = 160577\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\tCentering peaks of size 200 using a fragment length of 73\n",
      "\t\tFinding peaks on chr14 (minCount=3.6), total tags positions = 1197735\n",
      "\t\tFinding peaks on chr15 (minCount=3.6), total tags positions = 1175521\n",
      "\t\tFinding peaks on chr16 (minCount=3.6), total tags positions = 997210\n",
      "\t\tFinding peaks on chr17 (minCount=3.6), total tags positions = 1141355\n",
      "\t\tFinding peaks on chr18 (minCount=3.6), total tags positions = 951848\n",
      "\t\tFinding peaks on chr19 (minCount=3.6), total tags positions = 731845\n",
      "\t\tFinding peaks on chrX (minCount=3.6), total tags positions = 603921\n",
      "\t\tFinding peaks on chrY (minCount=3.6), total tags positions = 21035\n",
      "\t\tFinding peaks on chr1_GL456210_random (minCount=3.6), total tags positions = 580\n",
      "\t\tFinding peaks on chr1_GL456211_random (minCount=3.6), total tags positions = 912\n",
      "\t\tFinding peaks on chr1_GL456212_random (minCount=3.6), total tags positions = 641\n",
      "\t\tFinding peaks on chr1_GL456221_random (minCount=3.6), total tags positions = 495\n",
      "\t\tFinding peaks on chr4_GL456216_random (minCount=3.6), total tags positions = 1046\n",
      "\t\tFinding peaks on chr4_JH584292_random (minCount=3.6), total tags positions = 174\n",
      "\t\tFinding peaks on chr4_JH584295_random (minCount=3.6), total tags positions = 84\n",
      "\t\tFinding peaks on chr5_GL456354_random (minCount=3.6), total tags positions = 46\n",
      "\t\tFinding peaks on chr5_JH584296_random (minCount=3.6), total tags positions = 18\n",
      "\t\tFinding peaks on chr5_JH584297_random (minCount=3.6), total tags positions = 29\n",
      "\t\tFinding peaks on chr5_JH584299_random (minCount=3.6), total tags positions = 486\n",
      "\t\tFinding peaks on chr7_GL456219_random (minCount=3.6), total tags positions = 1\n",
      "\t\tFinding peaks on chrUn_GL456239 (minCount=3.6), total tags positions = 1588\n",
      "\t\tFinding peaks on chrUn_GL456359 (minCount=3.6), total tags positions = 378\n",
      "\t\tFinding peaks on chrUn_GL456360 (minCount=3.6), total tags positions = 259\n",
      "\t\tFinding peaks on chrUn_GL456366 (minCount=3.6), total tags positions = 320\n",
      "\t\tFinding peaks on chrUn_GL456367 (minCount=3.6), total tags positions = 109\n",
      "\t\tFinding peaks on chrUn_GL456368 (minCount=3.6), total tags positions = 82\n",
      "\t\tFinding peaks on chrUn_GL456370 (minCount=3.6), total tags positions = 296\n",
      "\t\tFinding peaks on chrUn_GL456372 (minCount=3.6), total tags positions = 137\n",
      "\t\tFinding peaks on chrUn_GL456378 (minCount=3.6), total tags positions = 294\n",
      "\t\tFinding peaks on chrUn_GL456379 (minCount=3.6), total tags positions = 196\n",
      "\t\tFinding peaks on chrUn_GL456381 (minCount=3.6), total tags positions = 237\n",
      "\t\tFinding peaks on chrUn_GL456382 (minCount=3.6), total tags positions = 56\n",
      "\t\tFinding peaks on chrUn_GL456383 (minCount=3.6), total tags positions = 256\n",
      "\t\tFinding peaks on chrUn_GL456385 (minCount=3.6), total tags positions = 159\n",
      "\t\tFinding peaks on chrUn_GL456387 (minCount=3.6), total tags positions = 648\n",
      "\t\tFinding peaks on chrUn_GL456389 (minCount=3.6), total tags positions = 302\n",
      "\t\tFinding peaks on chrUn_GL456390 (minCount=3.6), total tags positions = 142\n",
      "\t\tFinding peaks on chrUn_GL456392 (minCount=3.6), total tags positions = 640\n",
      "\t\tFinding peaks on chrUn_GL456393 (minCount=3.6), total tags positions = 1013\n",
      "\t\tFinding peaks on chrUn_GL456394 (minCount=3.6), total tags positions = 178\n",
      "\t\tFinding peaks on chrUn_GL456396 (minCount=3.6), total tags positions = 174\n",
      "\t\tFinding peaks on chrUn_JH584304 (minCount=3.6), total tags positions = 12003\n",
      "\t\tFinding peaks on chrX_GL456233_random (minCount=3.6), total tags positions = 1073\n",
      "\tTotal Peaks identified = 442609\n",
      "\t\tTags Used for cluster (less clonal tags) = 39585571.0 / 46329172.0\n",
      "\tExpected tags per peak = 3.958557 (tbp = 0.019793)\n",
      "\t\tThreshold\tPeak Count\tExpected Peak Count\tFDR\tPoisson\n",
      "\t\t17\t127170.000\t19.727\t1.55e-04\t9.86e-07\n",
      "\t\t16\t162096.000\t86.074\t5.31e-04\t4.30e-06\n",
      "\t\t15\t210299.000\t354.241\t1.68e-03\t1.77e-05\n",
      "\t\t14\t274657.000\t1370.393\t4.99e-03\t6.85e-05\n",
      "\t\t13\t359016.000\t4964.161\t1.38e-02\t2.48e-04\n",
      "\t\t12\t468111.000\t16766.179\t3.58e-02\t8.38e-04\n",
      "\t\t11\t603971.000\t52542.924\t8.70e-02\t2.63e-03\n",
      "\t\t10\t770757.000\t151958.954\t1.97e-01\t7.60e-03\n",
      "\t\t9\t967152.000\t403101.169\t4.17e-01\t2.02e-02\n",
      "\t\t8\t1191458.000\t974086.997\t8.18e-01\t4.87e-02\n",
      "\t\t7\t1437139.000\t2128013.623\t1.00e+00\t1.06e-01\n",
      "\t\t6\t1696506.000\t4168527.017\t1.00e+00\t2.08e-01\n",
      "\t\t5\t1957185.000\t7261340.948\t1.00e+00\t3.63e-01\n",
      "\t\t4\t2214250.000\t11167832.534\t1.00e+00\t5.58e-01\n",
      "\t\t3\t2214250.000\t15115221.923\t1.00e+00\t7.56e-01\n",
      "\t\t2\t2214250.000\t18106758.489\t1.00e+00\t9.05e-01\n",
      "\t\t1\t2214250.000\t19618186.251\t1.00e+00\t9.81e-01\n",
      "\t\t0\t2214250.000\t19999999.047\t1.00e+00\t1.00e+00\n",
      "\t90.00% FDR Threshold set at 8.0 (poisson pvalue ~ 4.87e-02)\n",
      "\tCentering peaks of size 200 using a fragment length of 71\n",
      "\tTotal Peaks identified = 429885\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\t1191458 peaks passed threshold\n",
      "\tTotal Peaks identified = 721042\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\tTotal Peaks identified = 485638\n",
      "\tCentering peaks of size 200 using a fragment length of 76\n",
      "\tTotal Peaks identified = 635441\n",
      "\tTotal Peaks identified = 612148\n",
      "\tTotal Peaks identified = 682952\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\tCentering peaks of size 200 using a fragment length of 77\n",
      "\tTotal Peaks identified = 740969\n",
      "\tCentering peaks of size 200 using a fragment length of 78\n",
      "\tTotal Peaks identified = 1191458\n",
      "\tCentering peaks of size 200 using a fragment length of 71\n"
     ]
    }
   ],
   "source": [
    "%%bash\n",
    "rm ./atac_peak_files/*\n",
    "chmod a+x ./*sh\n",
    "bash ./peakCalling_homer_idr.sh"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Run IDR"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {
    "scrolled": true
   },
   "outputs": [],
   "source": [
    "idrDirectory = './atac_idr/'\n",
    "scriptFile = open('./run_idr.sh', 'w')\n",
    "!rm ./atac_idr/*\n",
    "\n",
    "! if [ ! -d $idrDirectory ]; then mkdir $idrDirectory; fi\n",
    "replicateIndices = []\n",
    "\n",
    "\n",
    "# homer peaks\n",
    "counter = 0\n",
    "for treatment in sorted(set(filtered_summary_atac_frame['treatment'])):\n",
    "    samples = filtered_summary_atac_frame[filtered_summary_atac_frame['treatment'] == treatment]['simplifiedName'].values\n",
    "    \n",
    "    for i in range(len(samples) - 1):\n",
    "        for j in range(i+1, len(samples)):\n",
    "            counter += 1\n",
    "            sample1 = samples[i]\n",
    "            sample2 = samples[j]\n",
    "            peakFile1 = peakDirectory + '/' + sample1 + '_peaks.tsv'\n",
    "            peakFile2 = peakDirectory + '/' + sample2 + '_peaks.tsv'\n",
    "            \n",
    "            # determine IDR threshold based on number of peaks\n",
    "            # https://sites.google.com/site/anshulkundaje/projects/idr\n",
    "            with open(peakFile1) as f:\n",
    "                data = f.readlines()\n",
    "            len_1 = len(data)\n",
    "            with open(peakFile2) as f:\n",
    "                data = f.readlines()\n",
    "            len_2 = len(data)\n",
    "            max_length = max(len_1, len_2)\n",
    "            commandString = ' '.join(['python /home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py',\n",
    "                                     peakFile1,\n",
    "                                     peakFile2,\n",
    "                                     idrDirectory])\n",
    "            if max_length > 150000 + 35: # 35 is the number of header rows in peak files\n",
    "                commandString += \" -threshold 0.01\"\n",
    "            else: \n",
    "                commandString += \" -threshold 0.01\"            \n",
    "            if not counter % 12 == 0:\n",
    "                commandString += ' &'\n",
    "            scriptFile.write(commandString + '\\n')\n",
    "scriptFile.close()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/bin/idr --samples ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks_c57bl6_il4-24h_17-07-31-rep2_1_peaks_idr.out --plot --idr-threshold 0.01\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks_c57bl6_il4-24h_17-07-31-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il1b-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il1b-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il1b-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il1b-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il1b-24h_l20180218-rep1_1_peaks_c57bl6_il1b-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep1_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep1_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks_c57bl6_il4-24h_17-07-31-rep1_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_17-07-31-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_17-07-31-rep1_1_peaks_c57bl6_il4-24h_17-07-31-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il13-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il13-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il13-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il13-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il13-24h_l20180218-rep1_1_peaks_c57bl6_il13-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180305-rep2_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep1_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep1_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks_c57bl6_il4-24h_17-07-31-rep1_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il5-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il5-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il5-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il5-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il5-24h_l20180218-rep1_1_peaks_c57bl6_il5-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep3_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep3_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks_c57bl6_il4-24h_17-07-31-rep3_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180305-rep2_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep3_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep3_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks_c57bl6_il4-24h_17-07-31-rep3_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_veh-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_veh-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_veh-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_veh-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_veh-24h_l20180218-rep1_1_peaks_c57bl6_veh-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180305-rep2_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks_c57bl6_il4-24h_17-07-31-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_ifng-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_ifng-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_ifng-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_ifng-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_ifng-24h_l20180218-rep1_1_peaks_c57bl6_ifng-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_l20180218-rep1_1_peaks_c57bl6_il4-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_kla-1h_16-02-11-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_kla-1h_16-05-06-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_kla-1h_16-02-11-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_kla-1h_16-05-06-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_kla-1h_16-02-11-rep1_1_peaks_c57bl6_kla-1h_16-05-06-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il6-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il6-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il6-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il6-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il6-24h_l20180218-rep1_1_peaks_c57bl6_il6-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il23-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il23-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il23-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il23-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il23-24h_l20180218-rep1_1_peaks_c57bl6_il23-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep2_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep3_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_17-07-31-rep2_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep3_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_17-07-31-rep2_1_peaks_c57bl6_il4-24h_17-07-31-rep3_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_il4-24h_17-07-31-rep3_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_il4-24h_17-07-31-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_il4-24h_17-07-31-rep3_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_il4-24h_17-07-31-rep1_1_peaks_c57bl6_il4-24h_17-07-31-rep3_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_veh_18-01-16-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_veh_18-01-16-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_veh_18-01-16-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_veh_18-01-16-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_veh_18-01-16-rep1_1_peaks_c57bl6_veh_18-01-16-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_tnfa-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_tnfa-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_tnfa-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_tnfa-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_tnfa-24h_l20180218-rep1_1_peaks_c57bl6_tnfa-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n",
      "Performing IDR analysis on the following samples: /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_tgfb-24h_l20180218-rep1_1_peaks.tsv, /home/jtao/analysis/genomic_grammar_analysis//atac_peak_files/c57bl6_tgfb-24h_l20180305-rep2_1_peaks.tsv\n",
      "Output files will be written to: ./atac_idr/\n",
      "Using the following IDR threshold: 0.01\n",
      "Peaks will be ranked using: findPeaks Score\n",
      "Other available scoreColumns: ['Normalized Tag Count' 'focus ratio' 'findPeaks Score' 'Score']\n",
      "idr --samples ./atac_idr//c57bl6_tgfb-24h_l20180218-rep1_1_peaks.narrowPeak ./atac_idr//c57bl6_tgfb-24h_l20180305-rep2_1_peaks.narrowPeak --output-file ./atac_idr//c57bl6_tgfb-24h_l20180218-rep1_1_peaks_c57bl6_tgfb-24h_l20180305-rep2_1_peaks_idr.out --plot --idr-threshold 0.01 &\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "chmod: cannot access ‘./scratch/*’: No such file or directory\n",
      "Traceback (most recent call last):\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/bin/idr\", line 4, in <module>\n",
      "    __import__('pkg_resources').run_script('idr==2.0.3', 'idr')\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/pkg_resources/__init__.py\", line 750, in run_script\n",
      "    self.require(requires)[0].run_script(script_name, ns)\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/pkg_resources/__init__.py\", line 1527, in run_script\n",
      "    exec(code, namespace, namespace)\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/idr-2.0.3-py3.5-linux-x86_64.egg/EGG-INFO/scripts/idr\", line 10, in <module>\n",
      "    idr.idr.main()\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/idr-2.0.3-py3.5-linux-x86_64.egg/idr/idr.py\", line 828, in main\n",
      "    merged_peaks, signal_type = load_samples(args)\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/idr-2.0.3-py3.5-linux-x86_64.egg/idr/idr.py\", line 698, in load_samples\n",
      "    for fp in args.samples]\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/idr-2.0.3-py3.5-linux-x86_64.egg/idr/idr.py\", line 698, in <listcomp>\n",
      "    for fp in args.samples]\n",
      "  File \"/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/idr-2.0.3-py3.5-linux-x86_64.egg/idr/idr.py\", line 53, in load_bed\n",
      "    signal = float(data[signal_index])\n",
      "IndexError: list index out of range\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Final parameter values: [1.65 1.22 0.82 0.61]\n",
      "Number of reported peaks - 13704/43858 (31.2%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 13704/43858 (31.2%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [1.49 1.15 0.72 0.65]\n",
      "Number of reported peaks - 18521/64282 (28.8%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 18521/64282 (28.8%)\n",
      "\n",
      "Final parameter values: [1.67 1.23 0.77 0.70]\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 21744/56093 (38.8%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 21744/56093 (38.8%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Final parameter values: [1.92 1.22 0.86 0.59]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Final parameter values: [1.72 1.15 0.79 0.61]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Number of reported peaks - 23148/65424 (35.4%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 23148/65424 (35.4%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Number of reported peaks - 23487/71338 (32.9%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 23487/71338 (32.9%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Initial parameter values: [0.10 1.00 0.20 0.50]\n",
      "Final parameter values: [1.52 0.98 0.67 0.38]\n",
      "Final parameter values: [1.70 1.26 0.80 0.67]\n",
      "Number of reported peaks - 2139/19257 (11.1%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 2139/19257 (11.1%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 30138/81498 (37.0%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 30138/81498 (37.0%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [1.88 1.30 0.85 0.61]\n",
      "Final parameter values: [1.63 1.20 0.81 0.60]\n",
      "Final parameter values: [1.83 1.15 0.77 0.63]\n",
      "Number of reported peaks - 32039/88315 (36.3%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 32039/88315 (36.3%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 11557/39595 (29.2%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 11557/39595 (29.2%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 28193/76378 (36.9%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 28193/76378 (36.9%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [2.01 1.31 0.88 0.54]\n",
      "Number of reported peaks - 33375/100936 (33.1%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 33375/100936 (33.1%)\n",
      "\n",
      "Final parameter values: [2.01 1.26 0.87 0.55]\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [1.68 1.25 0.84 0.63]\n",
      "Number of reported peaks - 33581/97299 (34.5%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 33581/97299 (34.5%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 21784/65367 (33.3%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 21784/65367 (33.3%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [2.04 1.27 0.87 0.54]\n",
      "Final parameter values: [1.87 1.20 0.84 0.58]\n",
      "Number of reported peaks - 20373/60877 (33.5%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 20373/60877 (33.5%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 33550/100013 (33.5%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 33550/100013 (33.5%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [1.76 1.25 0.80 0.71]\n",
      "Final parameter values: [1.98 1.31 0.86 0.65]\n",
      "Number of reported peaks - 27711/65490 (42.3%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 27711/65490 (42.3%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [2.31 1.49 0.92 0.67]\n",
      "Number of reported peaks - 28890/69028 (41.9%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 28890/69028 (41.9%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 31554/64951 (48.6%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 31554/64951 (48.6%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Final parameter values: [1.90 1.27 0.87 0.59]\n",
      "Final parameter values: [1.96 1.23 0.85 0.59]\n",
      "Number of reported peaks - 31651/90757 (34.9%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 31651/90757 (34.9%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n",
      "Number of reported peaks - 29609/81268 (36.4%)\n",
      "\n",
      "Number of peaks passing IDR cutoff of 0.01 - 29609/81268 (36.4%)\n",
      "\n",
      "/home/jtao/code/seq_merge_pipe/run_idr_homerPeaks.py:178: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "  narrowPeakFrame['pValue'] = -1\n"
     ]
    }
   ],
   "source": [
    "%%bash\n",
    "chmod a+x ./scratch/*\n",
    "bash ./run_idr.sh"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {
    "scrolled": false
   },
   "outputs": [
    {
     "data": {
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YGjWx/Y/ruknwDPBlYAfiHpcOCcapdnAm8ClqV0LFwK/HI4Yc8v6TCIiIiIiIiIiIiIiKY7Fbgd\nWB7Yk44Og8oBlA6CpYFVgA9M+LxzHZF32B7J9XuSkigiYuH7FLAPsG/dgURERERExMD8N3AwcEjd\ngURE1MH2HZQZBp8Cfi1p+Qmf/wF4MaVTAUoHQecPwH3A/ra/O5Sg56HMMIiIWOBs/7juGKInVwN/\nqzuIiIiIiGgG28fVHUNERN1sHzXD5z+q1i84gLL48QbAUsAVlHUODrd9wcADncfSYRARETEP2V5U\ndwwRERERERERC43tK4B3VD8xQToMIqJX7wI+VncQERHzUOrHZvoU8M26g4iu5FprppRb85xPWQAy\nIgYr9WNEzAtj4+MjuXZDRERERERERERjVbm5dwCeCmwGrAosA9xMSW/5G+CMKmd3RETErKTDICJi\nAZE0BjwJeAqwHrAK5aZhNsZt7zeo2CIiIiIiYu4krUJZ3PhVwIqzOOQc4EO2fzjQwCIiYkFIh0FE\nxAIh6c3AvwHr93oO20v2L6LoRtXZszGlk2d5YGy2x9o+c1BxRURERMT8IWkb4BvAWrTbi+NM3nYc\nn7DP14F9bd8z6DgjIqK5soZBRMyJpGUoU19vtH1X3fGMIklLA98Fdq7emulBc6uneOJ+6UGugaSX\nA/sCWwHL9XCKcfJ9Pi+lfpzfJK0P7M4MaRyAE23fX1ecMTNJN1Sb19nerNZgYkpVx/izgG2BTYDV\ngDuAq4CzgZNsX19bgBENUHUW/IgyuKSz7X498Pvq9S5gJcpAFFHaia2Og1cAq0p6nu20/SOikSQd\nNKzfZfuQYf2u+SQzDCLiXyStB2wHrAP8E/i57fOn2Hcv4C3AE4AlqrevBL4HfMr2JYOPOAAkfR54\nLe0bgcuBX1EeQD+0ev9YynTlhwGPA5amfZNxInAdgO19hhn7KJO0GuV6eXr1VmcHzmy/nMcoqaQy\nM2TAUj8uHJI2Bg4Dnku7fGDxEZidrgQ+ZvszQwgveiCp1aFzne01aw1mhEhqXT/jMz14lLQ7ZSHP\nTafZ7Q7gs8BB6WQdHknP7MNp7qJ0tl6bTp/BkbQicAEl7Wjrmvs6cITtc6Y4ZiVgD+DA6jiqY99h\n+7DBRhyzJWlJ4PnAc4BHAGvQ7lA9CzjBtuuLMGJ+qdp+Q3mgPar32ukwiAgkrQz8F2XEycRR56cC\ni2xfVe27FGUK7O7V55ONUr8TeJPtrwwq5igkbQb8kfLQaxz4d+ATtsclnQTsxIQHypJWAPam5D1d\nA7gM2N32ecOOf1RVD1nOpqw1MVfpMBig1I8Li6Q9gC9RZvOMMXUKh4nGKTfsz7d98+AijF503DRe\nnw6D4ZD0SMpoZoBzbG85zb4fAd5d/bN13U3U2WH3a2BX29f2KdyYxgAeuvyDUl8ebfsnfTzvyJP0\nduBTlPK6C3i57e/P8tgVKAMXtq/eugFYy/Z9g4g1Zk/SDsBnWLxDdWJdeT/wVWB/27cOMbyIealj\nsMigjey9djoMIkZcNVLlNOCJPHB0ZauhYuDJtm+T9BngjUyf1maM0qh5he3jBxj+yJP0UcpN+Djw\nRdtv6Phs0g6Djs/XojzwfDQl/cZjc3M+HJIWAcfQvl4uBA6npD+53Pbt9UUXLakfFxZJL6F06LQ6\nWMeA+4DzmDyNw5Mo+aFb+45T0hRtndHP/VOlhpqrSynlcyNlZs8DOoFsX9aH3xMVSW+gzAYYB95g\n+4sz7AeLd9DdSXlguSwlHVhnB9448DNg+zzMHLyODoPpOk+n+l6bbl8o7Zq9bV/eY3jRQdJZwNMo\nf+N/s314l8dPnKGwk+0f9z3QESfpimrzJ7b3mmHffYHPA0uyeCfBVO3OcynldgMRI0zS6QxvhsGz\nhvF75pvkPI6IjwNbsHhlOzZhW8AHJB0NvIH2TYWBb1NGqK8CbEOZRjlOeSDzWUk/ToNmoLbu2P54\nNwfavlrSrpQZCmsCRwAv72NsMbWXdmz/EHhRFp+bl1I/LhCS1qTckLc6C+6ijNL8bGuGyCTHjAE7\nAB+m/H8wVr0eBLxvCGGPikvpzw3fGOXB86WTfJa1Xvpvm47tEyfboUq99zHa5XsPZRTtl21f0LHf\nKpR1mN5NSZs4RmnfvA74XN8jj8lMlhZx4vfdRFN1InT+e1vg55K2tH3lnCIMgIdXr7cCR3Z7sO1b\nJH0B+GDH+dJh0H9rU66P1afbSdKWlLZJa40JKNfP3yjpEJenzDporVcxRhnEcjTt2awRI8n2tnXH\nsNAtMfMuEbFQSdqAdu57KNOHtwFWoDzgeiHwF0rj5HXA62nfBBwGPNr2+20fZftQ27tScnzfUp1z\nNUoe7xicjavXv9m+dKqdJE36oKQacfkVSrnuVuU5jcF7fPV6H/DqdBbMP6kfF5zXUh4mjwM3AdtW\n5TNpZwGA7XHb/wdsCfx39fYY8BZJyw464BEzNsef2Zwn+usx1es104we34+yfhKU/PbPsP2Ozs4C\nANs32f4m8GRKPnYoZfauPscck7C9hO0lKJ0211L+9v8APkT53lqbMhNk2Wp7u+qzf1T7XkOZ0boc\nsCHwMtoPoccp62cdO5z/mgVvRcrf9I9zmOn26wnni/ocxeILUh8DbGJ7I9tPs/14SntxT+DvHfs9\nX9IuNcUcESMiHQYRo+2VtOuBX1Gmfv/M9h22/2n7e5QRXtcCD6Y8FBsHTrH9b5NNE7d9BrAv7Zvz\nvQf9HzHiWg/AJku1cHfH9nLTnKOVX3ZpFh8xGIOzGqXczrd9Td3BxKRSPy4sL+jY3t/2/5vtgVVZ\nvpoyawRKp9H2Ux8RPRhnSNPKo29aKU0unmafHTu232b711PuCdi+F9gHuKh662GSHjWnKGNWqkWp\nT6SsbfU5YDPbB9k+3fY1tu+ufq6p3jsI2Kzad83q2OfYvsz2/9jeEXgT7e+77SQ9ffj/ZQtOa5bG\nXNLidd4fTNlpHoMlaUfgUbS/+95q+9W2L+ncr7ruvgE8FfhTx/5vHlqwEQ0jafk+nmvHmfdamNJh\nEDHantGx/e7JRjnbvpoyWnaMMrII4JDpTmr7BOAP1TEbSlqvP+HGJDqn+U90S8f2OtOco/OB9bpz\njihmo5WG5qZao4jppH5cWDaqXm+kPYJ51mzfDXTmaN94qn1jTk6hPDDu5mff6thxyvfedPtE/7QG\nIky35s7m1evNwHGzOWlV1x7V8dYW3YcW3ZC0DmVk8xhwrO03275zpuNs32n7zZTZA0sCX67O1fr8\nSErqlJYX9zfykfRHSjltNodzaML5oh7P69j+tu3PTLdz1ebcg/Ysg2f386FoxALzbUlzft4taTvg\nu32Ip5GSyzNitD2yer3R9s+m2e9E4CPV9k22fzmLc3+fspgulPQrWexsMG6gdAZMlkro6o7tRwB/\nnuIcq3Vsr9qnuGJ6f6VM61+r7kBiSqkfF5blKDfZF85hEdXfd2wvM/eQovINyvo545QR6XcDb7T9\nj9meQNIx1eZdtr/a/xBjEtdTRpavNs0+q9NOn3J/F+f+bcf2Q3qILbqzL7AyJU3ie3o4/j2UWXkr\nUTroPtLx2Scoqalg8Y746M1xwC7AWpKea3vS9UOmUq3Ns0/1z7/MNOsnBuppHdsfm80Btn8v6UeU\nzoYlgCcBZw4gtoim2xn4EnMYMCJpa+AHtAeFjZzMMIgYba10NlM9SG75a/U6m31bzu/Yzqj1wbmI\nMspko0k+6yyDnaY5xw4d2xnxPhzHV6+bS0qnwfyU+nFhmfXD51nK4p19YntPYDdKaowxYFfgAkmv\nqzWwmEmrvDaWtOQU+9xavXa7Ts+9PUcVvWilbPtjNYq5K9VaMK2Zcy+Y8NlFtNc6yIy6ufs2JU3i\nGPB5SRt2efwHKWuFjAPv7G9o0aVW++862+d1cdwpHdub9jGeiIXmVZI+1MuBkrYCfkhZcHxkpcMg\nYrS1ppPfMt1Otm/r+OfNszz3tR3bWUh3cM6tXleXNPHB42m0UxbtLUkTPkfSFpTc3C2/nbhPDMSx\nwBWUG76Dao4lJpf6cWE5j3K9PWKah5szeUzHdjc39zED2z+g5HL+GqWcVgI+J+l0SXkgMj/9onpd\nianXP7qEUp7dluHDO7bTOTd461Pai9fOtOM0rqteN5jks79Vr5nFOkfVOh8voQxQWA/4laRFkqbN\nHCFpE0nfAd4L3A+8r6p3oz6tgSl/nWnHCf7Ssb1K/8KJWFBaAw/eK+n13Rwo6SmUGeStReG7vUYX\njKQkihhtt1MW65xuQdyJZjulvHM02VJdnD+6cwbw9mp7Zzpyxdr+u6SfAM+mLNL5C0mHA+dUuzyT\nsiDdspQG66XAbNKpxBzZvlnSKymjhF4v6WLbn6o7rlhM6seF5auUhyyrUdLf/Hc3B0taCngtpa78\nre3kfe4z2zdRRoN9C/gCZfTl1sD5kg4GDu0yrU0M1glA6yb8EMoghYm+R0mZ8VBJ21QLv8/GXh3b\nf+g9xJillavXNedwjtaxk3WCt9a5yMLmsyBp71ns9l+UAScPobT9Pynpx5TUeddTUrutSJmBvCVl\nVkHL8cAVkva2fWw/Y4+u3E65Xm6daccJOvfvpo0aMUreQHs9pP+SdJXt7810kKQnACfT/l68FNh+\nIBE2QGYYRIy2aygjvwaREqXzhqHbhlDM3qmUBucYsOcknx8A3EW5SVsF+ABlet0PgXdRHoi2vMN2\nbuaGxPbplAbI9cAnJJ0haQ9JD6seTka9Uj8uIFWe5x9RyvTTkp4022OrnM9HURaKvBd4y0CCDOBf\nZfUo4Mu0FxT/CHBOdSMX88NptNOrbSXp05PsczTtmVdHSppxhLmkt1Fy3Y9TcqyfP8MhMXdXU661\nR04yW3VGktajXLPjlO/OiVrfef/sOcLR8hVK/TfdzxHAGrQXwF2N0il+CPBZynfWf1K+r55c7TNW\nnf9lHeeJ+lxGKZMVZ9pxgs797+hfOBELh+2jgYOrfy4JfF3S06Y5BEmPAf6P8sxkHPg7sL3tvw8y\n1vksMwwiRtvfgE2ADSUtOcNCkMdSKs7fT7NPp84bjkwnHxDbd0h6O7AZMC5pedu3d3z+B0kvBr5J\nmWUwNslp7gMOsP3doQQ9IiR1s7DqGOUByb8WBJwkg9RUxm3n+7z/Uj8uPHtRFpzeGjhD0qHAZ21P\nmYZD0nbARykPXO4AXmv77GEEO8ps/xPYT9LxwBeBh1EWCP+VpP8EPmD7rjpjHHW275f0RqC1KPyb\nJW0GvMX2X6p9rpb0FkodKeDcqs3y/YkDFCStD7yfxRco/Pig/zsCKDNP16e0RT5JmYXVjU9Wx47T\nnsXa6eHVZ5fNIcZRNFmbvdP4hNep9h9n8dkdYx3vx2AtV9Vtk7mQkupwky7PuXbH9g09RRUxAmwf\nXHVo70cZfPIDSc+w/aeJ+0p6JGUg5urVW1cBz7Z9ydACnofygCFitF0IbEepC57I5I18AGwv6vLc\nj+3YHtm8b8Ng+6gZPv9RtX7BAZTFjzegpEG5gjJC8HDbFww80NHTunmezQ3fTDd7MXypHxtG0mzW\nAzkDeAQljcP7gX+XdC6Tp3F4CmWGSetaPhnYRNJBtg/p/39BTGT7FEmPpjyQfA3lenwnsLuk19g+\ns9YAR5zts6tOg89Vb+0IWNLPKaP0fkepSz9KyZ2+AfAd4GZJv6Vcc8sAG1Ouy85R0KfYPmZY/y0j\n7uvAi6rtl0q6HXib7WlnwEl6MPBp4KUdbx83YZ/NaOdqn22n+qi7jDzMXyieSVnLZTqrS9rA9t9m\n2K+lsw2ZTriI6b0OWAd4LmUm1smStrL9rwFb1ffUqbRT611NmVlw0bCDnW/SYRAx2n7Xsf1Mpnkg\n1oNWrrd7SP7Z2tm+AnhH9RPDM5sOgHQSzE+pH5vnP5j9Q5ZWZ96DKLMHnjzJPhNHYe5W/UBJ+xBD\nYPsW4HXVbIOjgA0pi+j+VNJRlPR6URPbX5B0P+XB8bLV20+vfjp1doyvwuILJU/8HjyRkl4lhsD2\ndyWdDmxLKadFwC6SjgN+Qun0uanafRVgc8r32J6Uzleq406fJEf0bh3bPyNmZLm3BSoAACAASURB\nVHvDumOIvprNzI+dKWv3zMZ2HdtZTyliGtVsyJcAp1Pa+usDJ0l6pu1/StqE8j23TnXIdcAOk81C\nGEXpMIgYbb+oXseA5wF9WXRV0uaUm4lx4Dzbd/fjvKOqSr8AcOFMswliXnlW3QHEnKR+bKZeOuBm\nOmbi5xn5WQPbP6nyy36CstjuGGXWwa7VLul8rYntoyT9DPgS8DQW72yb2PE23fVzHSXn8JFZ4Hro\nXkZ5oNL6floT2L/6mUpr9hWUB5d7TLLPSynrWNxPWT8rYlR007bYl1l0GFQjoR9Hue6utH1V7+FF\njIYqhfMuwNmUFGCPAb4n6fWUmQWtVLE3AjvazmCuSjoMIkaY7QskvZrSYLm3j6dujWIfA07p43lH\n1f6UhuEplNGV/yLptGrz/9l+z7ADi6nZPqPuGKJ3qR8b6UzyMH9Bs30b8CZJ/0N5OL0xZVTYbNK/\nxQBVo/GeIemplA6dnVl80fipyucOyoPq/wG+U80oiSGzfa2krYEjWXx2x3Sjo1ufHw+80fYD8qnb\nnvUC81FkoNCCsFGX+8+27fL26nWM0uaJiFmwfZ2knSmdBg+hzHL8PSVNM5SO7Z1t/7amEOelsfHx\n3FdFRH9Vi8a0Kt9Lbd9cZzxNV031H6fk833ubD+LiPkn9WNEf0hajrIo7ptoP9S8zvaaUx8VwyRp\nA8pi1WtQUtksC9wG3AJcSxmV/teJCyBHvSQ9A3gj8Bxg5Sl2u5mSOupI22cNK7ZRMEO7PwOFRpik\nLSnrvkBpQ8523YOIACQ9CfgpsDzttuOtlM6Cs2sLbJ7KDIOI6DvbyafYX1kQN2KBSP0Y0R+27wDe\nKulI2gvV3VNjSDFB9TArD7QapuoAOAtA0iMoi1WvUn18E/C35HeuzbaU+4I7a44jamD7l3XHENFk\ntn8t6cXA/wJLArcDu6SzYHLpMIiImP9uAVYEVq07kIiIiPnE9oWURVkjos+qjoF0DgxXBgpFRMxA\n0kFzOPx3wBOBXwLPkjTt2oO2D5nD72qsdBhERMx/lwGPBh4naS3bV9cdUPSfpBWArYAnUXIrrgyM\n2d6v1sAiIiIiYlgyUCgiYmb/wdzXLtuu+plJOgwiImJeOovSYbA0cI6ko4G/s/hCrOtK2nuuv8j2\nsXM9R3RH0lrAgcAiSj7FljFKI+gBHQaSTgEeXn2+g+2LBx9pRERERAxYBgpFRMzOMGZijew6S+kw\niIiY/z4PvAZYAlgPmDj9boxyY/HlPvyudBgMkaTtgK9TZhR00+D5LvA5SgNmL+Dg/kcXEREREUOW\ngUIRETM7kxF+mD8MY+Pj+ftGRJukZYENgZWAa2xf2uN5tgfWhTRG+0HSm4HDKZ0GgzJue8kBnj86\nSHoK8FNgWdqdBZdQcio+BXgoU5SJpJWAa4ClgN/a3mIoQUdfSPoCpezGk3KqOVJu/SfpmCH9qpRZ\nH6XcFjZJywBPAB5FWex4eboY1DCquZ77RdJjgd9Q2vyt2aYtrXLoy0OctPv7L/VjRCwU6TCICAAk\nPRz4MLAL5QFmy5XAfwMfs31TF+c7CdiR0pjJbKY+kPQY4NWUh8mrUx5cbUC5abgLmPOUZdsbzfUc\nMTNJSwJ/pJ1W6E/A62yfVX1+ErAT03TiSDqZco3dD6zRzfUZ9ZJ0B2XkYG7WGyTl1n+S7mdIo8NS\nZv2TcluYJK0JfBDYA3hwr+dJmc1dBgo1V+rHiFgo8hAvIpC0OyUtytI8cATRQ4F3Aq+R9Frb3+ni\n1MPIKTcybP8eeFvne1WjFOB0288dflTRo1fQ7iy4EHia7X92eY5fUToMxoDHAD/ra4QxaBNHDUYz\npNz6L/lnmynltoBI2gI4GViNuZVtyqwPbH9G0hkMeKBQDEzqx4hovHQYRIy4Ki3Ktyj1wWQNj9Z7\nqwLHS/oMsL/tNFIievf8ju039dBZAHBBx/ampMMgIprnq3UHED1JuS0gVZrDH1EeSne2768CLgdu\nqyOuUZeBQo2V+jEiFoR0GETE0bQ7C8aA/wd8H7iBspbBi4FNOj5/M/AQSa+0ff9kJ4yhy0yO5mmt\nOXCV7TN6PMf1HdurzjGeiIihs71P3TFE91JuC85bgDVpt/WPBj5h+6Jao4pooNSPEbFQpMMgYoRJ\n2oGyoNl49fM225+ZsNt7Je1JyaPZmqb8MmBJSS9Pp0G9bA8yt2kMTuvGfC4343d2bC8zt3AiIiJi\nRO3asf0h2wfVFknMRgYKRUTEwKXDIGK0vbBj+7OTdBYAYPu4Ko/mCcCTKA3VFwNLSNrD9n2DDzVi\nQelHSq/OWQVZ8LjPJF08wNOng2dAUm4REV3btHq9DfhQnYHE9DJQKCIihiUdBhGj7anV6/3Ah6fb\n0fblkrahrHfQGon0QuBbkl6WToOIrlwDbASsP4dzPHbC+aK/NqSdnqHfBnXeSLlFRHTrwZT67Xzb\nd9cdTERERNQvPdQRo209yg3Cn2zP+MDR9h3A7pROg9ZDk90pnQZLDizKiIXnj9XrBpI26fEcL+jY\n/uUc44mpZYH3Zkq5RUTMzpXV6z21RhERERHzRmYYRIy2lavXq2Z7gO37JL2CclPxSspDmVanQWYa\n1EjSw4C9ga0pa1OsAizfxSnGbed7YThOBnaptv8d2K+bgyXtAjyZdoffP/obXgD30R5YcTJwdR/P\nvRcZqT4oKbcGkXRMxz/Hbe83xWdztdi5Y25SbgvOHyizszasN4yI5kv9GBELRR4MRYy2uyj1wIrd\nHGR7XNKrKA9mXkW70+CbWdNg+CSNAR8E3km7Xs9DrfntOEqZrQwskvQr21+czYGSHg98peOtw/sf\nXgAGHkmp375p+9h+nVjSHiQf/qCk3JplEYvPBtlvms/mKg9W+mcRKbeF5GuUdKPrS3qs7fPrDigm\n16d1eu4CbgauBc4DzgJOtZ2Zef2xiNSPEbEAJCVRxGi7lvJgeb1uD6walftSHly2Hk6/EPiGpNQt\nw/V54L3AUtW/01kwz9m+idJh0CqrIyV9TdLjpjpG0iaSPkK5sVudcsNxAfDlQcc7on7Tsf3E2qKI\nbqXcmmeMqb+3xvr0E/2Xcls4TqCkNhwDDks7fl7bENiA9oyQyX42mGGfzSizVJ8LvA84CbikGgwW\n/ZH6MSIaLzMMIkbbHykLr64jaX3bl3VzcDXToDWyYRHlAeaLgG+Q+mUoJG0LvIb2aJW7KTd+ZwCX\nA7fVE1nMxPZh1WyBvSjl9wrgFZJuAJZu7Sfp98CawBrVW62bhBuB3WzfO7yoR8q5lLIB2KLOQKIr\nKbdm+WqPn0W9Um4LSJVudA/gZ8C2wHck7VMNboj5p/Nh8fgk7098mDxxn8keNq8PHCPpWbYXzTnC\n0Zb6MSIWhDzQixht59LOo74TcFS3J5ii0+DFZMHJYXl1x/afgV1s/7WuYKJr+1IWG3wn7Ru41uyB\n1jX0yI7PWu9dBLzAdj+mpsfkzq1ex4ApZ37EvJNyaxDb+/TyWdQr5bawSHpmtfkO4LPA84FLJX0T\n+DllrbO7Zns+22f2PchoaV1fDwYOogwmGQMuA06nDAZrdfSsQmlDbkvpEBgHrgEOoaSVXQt4KrAD\n5bnQGLCXpL/a/uDg/1MWptSPEbFQjI2P55lexKiS9CzgJ5QG5C9tP30O5xoDjqbdafCvB5y2l5xj\nqDEFSZdQph2PA1vY/m3NIUUPJG0JvIeSQ3i6VADXA4cBR9i+dRixjSpJD6bk+G15pG336dx3UHLh\np37ss5RbRER3JN3P5CPVe3lQMG47gxIHSNJ6wI+BhwOXAm+z/cMZjnkeZc2rDSlr/exg+x/VZxtQ\nRr63Oo7uADayfc0g4o+IiGZIfsKI0fZz4JZqe8vp8qfPpFrTYD9KPvUxMsNgWNai/K0vSmdBc9n+\npe3dgIcAu1FGjX0a+BLwScqov6cBa9v+SDoLBq/6G/+F9vT9fubD/xBwMGWUX/RRyi0iomedHQW9\ntOOTW33AJD0I+BZlHYI/A1vO1FkAYPt/ga0oM1QFfEvSktVnf6PMNG8tdr0sZQBYRESMsMwwiBhx\nkr4BvKz65/dsv7AP5/wi7VQ5GYk5QJKup0w5/qntZ9cdT0REREQ0RzXDoF/S7h8gSS+jrBU3Dmxn\n+4wuj98WOK06/uW2j+/4bBfgf6vPTrH93H7FHRERzZPpghHxNsoIZoC+3DDYfq2kU4Hl+3G+mNZl\nwKrASnUHErMnaT3bl9cdR0RERIw228k60ByvrF6v6LazAMD26ZL+ATwU2As4vuPjk4HbgeWAzeca\naERENFs6DCJGXJWfsu85Km3/T7/PGZM6kbKw56MlLWv7zroDilm5VNJplJyxJ9i+o+6AIiIiImJe\nexRlBsBf5nCOvwDrVuf6F9v3SboQ2AJYfQ7nj4iIBSCjCSIimu1LwF2UhThfU3MsMXtLANsDxwJX\nSTqmmiYeERER0VeS3lr9PL/uWGJO1qlel53DOZapXtee5LOb+nD+iIhYANJhEBHRYLYvAd5FWWTu\no5K2qjmk6N6KwKuAn0i6RNLBkjatO6iIiIhYMA4HDgNeP/GDatDCMZLePvywoku3UNr8m0tautuD\nq2NaMwtunWSXVmfC7b2FFxERC0U6DCIiGs72fwHvpeQc/amkQyStM8NhUa+XAD8E7q3+PVb9bAAc\nCFjSzyW9RtLKNcUYERERC98iysCFHWqOI2bWSkW0IrBvD8fvVx07VVqjdavXK3s4d0RELCBZwyAi\nosGqPPgtNwKrAe8D3ifpUuAqSsqi2Ri3vX1fA4xJ2f4O8B1JawCvoCw8t0X18Vj1umX182lJ36ek\nLzrFdl8WJ4+IiIiRMV53ANEX36e0DceAQyX9yfbpszlQ0rOAT3S89b0Jn68MbEj5f+WifgQbERHN\nlQ6DiBEl6Zgh/apx2/sN6XeNom1Z/CZwnPYD540oDf/ZGCM3k0Nn+zrgCOAISZtTRvjtyf9v796j\n5arqA45/r4C8RBDQhRh5aPWHqND6AAULSBWFViq+lUoScVGtUFsRW7usgtUlBZfio1XSVSRxpVQt\nCBGfIKCihPoAiw9+pQoBqQYoAotIEkKmf+xzuJPJzNyZe+fOZO79fta6a2bO7L3P75yTO7mzf/vs\nXUZ41ddxO+A11c/qiFgOLMvMG0YQ8rzg5+N48rpJUkdrgB0B71ocb+cCfw08lnI9L4uIJcCnO/1d\nGBHPBN5KWeusnmHizqqtZi9h8vvAysGHLkkaJxONhv1D0nwUERsZUgdxZm41jP3MR9V1HJSG12r0\nImKCsiDyCcBxlC+Ezerf2x8D5wMXZOadQwtwHvDzcTx53SSpvYj4ORCUxMHjM/P+pvfqz86vZ+Yx\nIwpRPYqIPwYuogz+bB7wcxdwI5MLF+8C7AfsXr2uB6KsB16RmV9paffLwNFVe8/JzOtm6xgkSVs+\n7zCQ5reJqYvMmFnJ2XXGqAPQYGVmA7gcuDwidgReRZmy6AjKyLD69/ZAygKGZ1HuQtBg+fk4nrxu\nkrS5lZSEwQ7AtyLi48BtTK6lBLBrRBw20x1l5rdn2oY6y8wvR8SrKYNGdqk2T1DuOti9pXj9f2L9\n/9Y9wMLWZEHl08ASYKPJAkmSCQNp/lo66gA0c5lpwmAOy8w1lN/VpRGxgHLXwZ9RRoxB+SK4zYjC\nm8v8fBxPXjdJau9fKdMeAvw+0DqF2wTwXODKGe6ngX0Msy4zV0TE/sAHgdcB21dvdUqarwUuAN6T\nmb/p0OaXBh6oJGlsOSWRJEljJCIOotxZ8Pxqk1NJSZKkriLiTOBdLZub176aacfABP5NMnTVYsVH\nAgcDezN518E9wCrgWuCKzLx3NBFKksaRCQNJkrZwEfEEyrREJ1CmFKj55VySJPUkIv6EsvjtQcBu\nlLsBmpMGM+XfJJIkzQEmDCRpjEXECdXT2zPzm9Ns4whgL4DMXDag0DRDEbEDZf2CEyjrF0yw+Rf6\nDcBXM/NPhxudJEmaC1z0WJIktXJ+QUkab+dTfckDppUwAN4OHFu1Y8JgxCLiRZQkwXGUxQlh80TB\njynztS/PzDuHGJ4kSZJGwIFCkqRhMWEgSYLB3YquaYiIp1GSBMcDT6g2T7DpNAGrgeXAssz8r6EH\nKUmS5ir/DhwP5+NAIUnSEJgwkOapiDiv6WUjM0/s8N5MbdK2pCIidgPeQEkUPKva3PqFfT2wgnI3\nwdcz86HhRTh/+fk4nrxukjQt+1aPD4w0Cg2TCSJJUlcmDKT5axFlZEntxC7vzZQdK1u2R1aPD440\ninkkIi4BXsrk/8OtX9yuoSQJPpeZ9w4zNgF+Po6rRXjdJKkvmblq1DFIkqQtiwkDaX6rOynbdaIM\nauSJK6tv+fapHu2YHp6XMfm7Uf+u3Qp8ljLl0E0jiUrN/HwcT143SZI6c6CQJGlKJgyk+WvpNN/T\nHBIRRwFPo3SA2Uk9XBPA/cCFwNLMvGq04aiJn4/jyesmSW04ZZua7FM9OlBIktTRRKPhIClJGgcd\nvtAtonT2/y9wWY9NTQDbA08FDgAeUbXxocx8z8wj1VQi4nJKB+aFmfm7UccjSZLmrojYSNPdUZm5\nVaf3Zqq5bQ1W07X6emYeM436RwFfq9q4JjNfMOAQJUlzhHcYSNL4WETnaTb2BBZOo816io41wJLp\nhaV+ZeaLRh2DJEmaV5yybYxMcefHM/u4M6R1oFDtqmmGJkmaB0wYSNJ46fSFbiZf9G4HFmbmrTNo\nQ5IkSVsmp2wbP4twoJAkaUSckkiSxkREfKbN5oVMTkl0eY9NbaTMnf9r4IfAFZn50ECClCRJkjQj\n1fRDs6EeKHTFLLUvSZoDTBhI0hib6VymkiRJkrYsDhSSJI2SUxJJ0vgb1LyzkiRJkkYsMxe3bouI\nehqiG9q9L0nSoJgwkKQxlpmPGHUMkiRJkobCgUKSpFnnlESSJEmSJEmSJAlHpkqSJEmSJEmSJBMG\nkiRJkiRJkiTJhIEkSZIkSZIkScKEgSRJkiRJkiRJwoSBJEmSJEmSJEnChIEkSZIkSZIkScKEgSRJ\nkiRJkiRJwoSBJEmSJEmSJEnChIEkSZIkSZIkScKEgSRJkiRJkiRJwoSBJEmSJEmSJEnChIEkSZIk\nSZIkScKEgSRJkiRJkiRJwoSBJEmSJEmSJEnChIEkSZIkSZIkSQK2HnUAkiRJkkYvIg4HrmzatCgz\nl40qnnHj+duyRcTewM1Nm07PzPePKh5JkqQtlQkDSZIkSc0aow5gzHn+tmxeH0mSpC6ckkiSJElS\ns4lRBzDmPH+SJEkaWyYMJEmSJEmSJEmSCQNJkiRJkiRJkmTCQJIkSZIkSZIk4aLHkiRJkopZm3s/\nIvYCng3sCewMrAbOz8yHpqi3FXAw8GTgcdXmO4CfZOZ1M4zpCcAzgH2rmDYCdwO3ANdk5u/6bHJW\n1y6IiN8D/gBYQPke9wvgisy8Z4p6TwWeBzweWA+sAi7PzPsGENP+wAGUa7M9cCdwM3B1Zj440/ab\n9rMrcCiwF7BjtZ8fZOYNfTTj2hKSJEk9mGg0GqOOQZIkSdKIRMQtlI7YflyVmUc2tfEZYGH1spGZ\nW1XbXwicQensbe6wbQCP6dRpHRFPBE4HXkHpzG/n18DHgHMyc/1UAUfEBHAY8DrgKEqioJMNwFeA\nD2TmD6Zo9xZmeP6qdjqdwz+inItD27SzlnIO3tvaQR8RhwFnA89tU+9B4OPA32fm2n4Cj4gdgHcC\nb6Lzcd8P/Bvwvsxc3UOb7wPe17Rpn8y8tUrqnA0cB2zbpupNwGmZuaJL21dRrns/bsnMJ/VZR5Ik\naU5wSiJJkiRpfmtUP/2Un3J7RPwdcBnwgn72ExGnAAksBh7dUre5jT2AM4HrqzsYprIIuBL4cyaT\nBa3t1m1vBRwLrIyI06Zod1Dnb7P3IuIdwDcoyYLWGBuUTvS/AVZExCOa6r0duIKSLGhXb2vgVOCS\niNim18Aj4g8pdzaczmSyoN352xE4Ccgq4dGrh9uokk3XURI8j+xwHE8BLo6IU6dos/lRkiRJXZgw\nkCRJkgSbd6i260zv1vn68B0EEfE64APVtgYlAXAJ8Hnge5QR/JuJiDMpI+abR5OvA1YC/wF8Afgh\nUE9l1AD2A74bEXtMcXz1d5/6ONYA/wmsAJYDFwHXU0bfNx/TmRHx1inartttfd3P+av3B0BEvBb4\ncPVyI/ADyvF/Ebi1pfxRlE58IuKNwEer9zZSztcXquNb1VLvRcB7ejg2IuLllORFPTVUo2r/p5Rr\newFwFfBAU7VHA5f2kTSo43pG1eZu1X5WAZdW+/gOZWqlOgaAf6zuqOik3fnudH36TQBJkiTNKa5h\nIEmSJM1vh1K+Fzyf0iELpcP0NEonfTudprGpO1qXVM+/C7ytda75qnP//pZtxwPvqupNUDr03wss\nycw1LWWfSOkUP64qvyewFHhJl+OEMo3RecAlnaYaiojdgbdTjn+bKpYPR8SlmXlbmyqDPH91XYBP\nVc8vBv6qdd8RcRLwz1V8E8CpEXFxta1BSRC8o029twCfbKp3WkSck5m/7RRQtQ7CZykj/esk0KeB\nD2Xmr1rK7kC56+HvKEmabYFlEXFAZv5fl+NuPvallLsUrgNOycxrWvaxB3A+JVFS/3s5m7LeRavX\nAtsBT6QkG+p9fAw4p0McbRNakiRJ84FrGEiSJEkiIg6nTNkDpVN1cWYu67FuPf9+3XnboExH9LJe\nFr+NiMcC/wM8qqp/N3BYZv5sinpLgDc3xXxsZn65Q9nHAXdnZk+dwdWI+ouY7GA+OzP/tkv5aZ+/\nqn67c7gsMxd3qfNB4N1NMd5LWfPhM5n55i71zqQkZ+pYT87MT3Upv5IyvVF918IbM/OCTuWrOsdT\nkgx1bB/JzLbTOzWtYdB87N8FXpKZD3Sosy1wA2VB7LrOMzLz5x3K701ZkLmO54zMfH+3Y5AkSZqP\nnJJIkiRJ0qCtoXSYT5ksqJwC7MRkx++bpkoWVE4GbmOyE/gvOxXMzDt6TRZU5S8GLmRyJP5req07\nILcDfzFFmY9ROvBru1DOx8lT1Psom069c3inghFxJHBQ9bIBfHyqZAFAZi6nTEFVn78TI2L7qepV\n1gGv75QsqNpfB5zFpotp97u4sSRJklqYMJAkSZI0KHWH/+cy89d91DuJyc7r6zNzRS+VMnM9Zfqj\nulP6iIjYro/9TqU5jr2rOyFmW30Oz+3WYQ4lCQLc2FJvSWZ2m/KIzFwN1CPxJ4ADuhR/S1O5DZS1\nKXr1iabnO1Omb5pK/e/n9h7KfrWpDsCBfcQmSZKkNlzDQJIkSdKgfanXghHxdMpCuvWI9y/2ua+r\nm55vTZnH/lt97H+CMhXSTpQ1C5o91PJ6P+DOPuObrst6LPcLYP8Z1uuWCDmCyQ7572Tm3T22D3At\nZRHp+nvnocDlXcrXSY+v9dJ4Zt4eEWuAHapNw0joSJIkzWkmDCRJkiQN2vV9lD2keqw7i1dX8833\nqvU7zT50SRhExFbAiylTDD2HkgTo9r2onlcf4DF9xDVT2WO5+1pe//c06j26XYGIeAqwO5MJg1V9\nXpsJyroKu1Wv9+mx3o1TF3nYvUwmDNoehyRJknpnwkCSJEnSoN3VR9kF1WPdMX/uNPbX3Km/a6dC\nEXFo1f7+ncpMYWgd0pl5b49FN1mXYZr1On0vXND0fAJYXP30q044dLw2LXo9Bih3MNRa7xCRJElS\nn0wYSJIkSRqozPxdH8V77UTupnnh20e1KxARxwAXUTqV6wRDo13ZLubbGnCDuDYweX3aXps2Nk5d\nRJIkSbPBhIEkSZKkUWodFd5vJ36ridYNEbErsKxlX7+stn0PuBlYDazNzA1N9Q4HrpxhPONs0NdG\nkiRJWzgTBpIkSZJGqV5Etx7xf3RmfmPA+3gbZbR83eG9HFicma2LGrfaacBxjJvmBY4bwFmZ+e5R\nBSNJkqTZN99uqZUkSZK0Zbmj5fVjZ2Efx1SP9SK8J/WQLADYYxZiGSet12b3kUQhSZKkoTFhIEmS\nJAlGN93Mypb9HzQL+3hy1X4DuDoz1/ZY7+A+9jEXp+v5CbCmej7B7FybYZmL10eSJGngTBhIkiRJ\nAlhXPdYdq48c0n6/D9xXPZ8AXh4Rg546deem5/d1LNUkIrYDjqP3juZRnb9ZU63n8G0m14V4ekTs\nN8KQZmJdy+uxvz6SJEmzwYSBJEmSJChT9TQbynQ81dRA5zHZKb0AOGXAu7mn6flTeqxzKmXdg16N\n5PwNwbnVY4Nyjc4cYSwzMVevjyRJ0kCZMJAkSZIE8EtgQ9PrFw5x32cBD9DUKR0Rr+yngYjYIyKO\n7vD2DVW7E8BzIuKQKdp6KfBe+pvGZpTnb9Zk5grgOibP38si4sMRMdG95qSI2C4iXj9bMfaimobq\nturlBHBYP8cgSZI0Xwz6Vl9JkiRJYygz10fEtcCh1aYjIuJfgAuAW4EHm4qvzczVA9z3byLiJOCz\n1aatgS9ExFLg7Mz8Wbt6EbETcBTwKsr0QRcBX21T9ELgSCYTEl+MiMWZ+ZWW9h5FubPg3VUMd9Hj\nIsyjPH9DcDxwLbBT9fodwEER8X7gm5m5WWIlIrYBDgFeAbyekky5YDjhdvRtyrE0KOtaXFhdo1+w\n6ZRFGzLz9hHEJ0mSNHImDCRJkiTVPsFkh/cEcGL10+oqSgf8wGTm8oh4EnB6te8GsBBYGBG/oizA\nezewDbALpcN3XyanMup2N8B5lE7uJ1evdwcujYibKaPn1wF7As8Dtq3K3AWcBpw/RdvNRnb+ZlNm\n3hgRrwU+D+xYbX4B8A3g3oj4EXAn8BBlvYgFwNMo16r2m+FF3NE/AW9g8t/My6ufVrcATxpSTJIk\nSVsUpySSJEmSBEBmfh74CKWDvP4Z5v7/gTIavXW++QXASymdva8GXkzp0K0TC3Wcd3dodx1wLKXT\nur7LAErCoR4BfzglWdAAVgNHA6uqcj1NXTPq8zebMvNrlDsGbmLTY9uZlrPFtAAAAi9JREFUMv3S\nayjn8RjgACaTBXXZttdmQOrpkrrKzJWUO0g2MMeujyRJ0qCYMJAkSZL0sMx8J3AwZTT29ykj7dex\naSd4u47WgXSSV53u+wBnUEZ6t+639ecm4JPAIZl5cpd2fw48C/h3Nu0wbv75LfAp4MDM/GHLcfUa\n/3TPHz2838lQ6mXmT4D9gTcBPwI20v3arKZMQ/RK4MBZOoa+6mbmOZSExtnA94A7gLVtYpckSZqX\nJhoN/xaSJEmStGWKiH2BZ1OmEXoMsB64h7LI8E8z845ptLkbcBiwF+WugtWUdQauzswHu9XVpIjY\nFXg+sAewW7X5Psriwj/LzJtHFZskSZKmx4SBJEmSJEmSJElySiJJkiRJkiRJkmTCQJIkSZIkSZIk\nYcJAkiRJkiRJkiRhwkCSJEmSJEmSJGHCQJIkSZIkSZIkYcJAkiRJkiRJkiRhwkCSJEmSJEmSJGHC\nQJIkSZIkSZIkYcJAkiRJkiRJkiRhwkCSJEmSJEmSJGHCQJIkSZIkSZIkYcJAkiRJkiRJkiRhwkCS\nJEmSJEmSJGHCQJIkSZIkSZIkYcJAkiRJkiRJkiRhwkCSJEmSJEmSJGHCQJIkSZIkSZIkYcJAkiRJ\nkiRJkiRhwkCSJEmSJEmSJGHCQJIkSZIkSZIkYcJAkiRJkiRJkiRhwkCSJEmSJEmSJGHCQJIkSZIk\nSZIkYcJAkiRJkiRJkiRhwkCSJEmSJEmSJGHCQJIkSZIkSZIkAf8PPQLvx/iWdEUAAAAASUVORK5C\nYII=\n",
      "text/plain": [
       "<matplotlib.figure.Figure at 0x7ff281dad2e8>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# pick the IDR results that have the most peaks\n",
    "idrDirectory = './atac_idr/'\n",
    "treatment_bestIDR_dict = {}\n",
    "treatment_peakNumber_dict = {}\n",
    "for p in os.listdir(idrDirectory):\n",
    "    if 'idr.tsv' in p:\n",
    "        with open (idrDirectory + '/' + p) as f:\n",
    "            data = f.readlines()\n",
    "        numPeaks = len(data) - 1\n",
    "        treatment = p.split('_')[1]\n",
    "        if treatment in treatment_peakNumber_dict:\n",
    "            if treatment_peakNumber_dict[treatment] < numPeaks:\n",
    "                treatment_peakNumber_dict[treatment] = numPeaks\n",
    "                treatment_bestIDR_dict[treatment] = p\n",
    "        else:\n",
    "            treatment_peakNumber_dict[treatment] = numPeaks\n",
    "            treatment_bestIDR_dict[treatment] = p\n",
    "\n",
    "            factors = []\n",
    "treatments = []\n",
    "numPeaks = []\n",
    "for treatment in treatment_peakNumber_dict.keys():\n",
    "#     tokens = treatment.split('_')\n",
    "#     strains.append(tokens[0])\n",
    "    treatments.append(treatment)\n",
    "    numPeaks.append(treatment_peakNumber_dict[treatment])\n",
    "\n",
    "idrPeak_frame = pd.DataFrame({\n",
    "                 'treatment':treatments,\n",
    "                 'peaks': numPeaks})\n",
    "    \n",
    "idrPeak_frame.index  = pd.MultiIndex.from_arrays([list(idrPeak_frame['treatment'].values)])\n",
    "# idrPeak_frame = idrPeak_frame.sort_values(inplace=True)\n",
    "sns.factorplot(x='treatment', y='peaks', data = idrPeak_frame, size =8, kind='bar')\n",
    "plt.xticks(rotation=90);\n",
    "# plt.ylim([0,30000])\n",
    "    "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 125,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "c57bl6\tifng-24h\tC57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180305-rep2\tc57bl6_ifng-24h_l20180218-rep1_1_peaks_c57bl6_ifng-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\til13-24h\tC57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180305-rep2\tc57bl6_il13-24h_l20180218-rep1_1_peaks_c57bl6_il13-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\til1b-24h\tC57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180305-rep2\tc57bl6_il1b-24h_l20180218-rep1_1_peaks_c57bl6_il1b-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\til23-24h\tC57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180305-rep2\tc57bl6_il23-24h_l20180218-rep1_1_peaks_c57bl6_il23-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\til4-24h\tC57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180305-rep2\tc57bl6_il4-24h_l20180218-rep1_1_peaks_c57bl6_il4-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\til5-24h\tC57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180305-rep2\tc57bl6_il5-24h_l20180218-rep1_1_peaks_c57bl6_il5-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\til6-24h\tC57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180305-rep2\tc57bl6_il6-24h_l20180218-rep1_1_peaks_c57bl6_il6-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\tkla-1h\tC57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-rep1\tC57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06-rep2\tc57bl6_kla-1h_16-02-11-rep1_1_peaks_c57bl6_kla-1h_16-05-06-rep2_1_peaks_idr.tsv\n",
      "c57bl6\ttgfb-24h\tC57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180305-rep2\tc57bl6_tgfb-24h_l20180218-rep1_1_peaks_c57bl6_tgfb-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\ttnfa-24h\tC57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180305-rep2\tc57bl6_tnfa-24h_l20180218-rep1_1_peaks_c57bl6_tnfa-24h_l20180305-rep2_1_peaks_idr.tsv\n",
      "c57bl6\tveh\tC57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep1\tC57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep2\tc57bl6_veh_18-01-16-rep1_1_peaks_c57bl6_veh_18-01-16-rep2_1_peaks_idr.tsv\n",
      "c57bl6\tveh-24h\tC57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180218-rep1\tC57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180305-rep2\tc57bl6_veh-24h_l20180218-rep1_1_peaks_c57bl6_veh-24h_l20180305-rep2_1_peaks_idr.tsv\n"
     ]
    }
   ],
   "source": [
    "outFile = open('./best_samples.tsv','w')\n",
    "if not os.path.isdir('./atac_idr_peaks/'):\n",
    "    os.mkdir('./atac_idr_peaks/')\n",
    "else:\n",
    "    for f in os.listdir('./atac_idr_peaks/'):\n",
    "        os.remove('./atac_idr_peaks/' + f)\n",
    "for key in sorted(treatment_bestIDR_dict.keys()):\n",
    "    p = treatment_bestIDR_dict[key]\n",
    "    tokens = p.split('_')\n",
    "    strain = tokens[0]\n",
    "    treatment = tokens[1]\n",
    "    sample1 = simpleName_originalName_dict['_'.join(tokens[:4])]\n",
    "    sample2 = simpleName_originalName_dict['_'.join(tokens[5:9])]\n",
    "    outFile.write('\\t'.join([strain, treatment, sample1, sample2, str(treatment_bestIDR_dict[key]),'\\n']))\n",
    "    print('\\t'.join([strain, treatment, sample1, sample2, str(treatment_bestIDR_dict[key])]))\n",
    "\n",
    "    if treatment_bestIDR_dict[key]:\n",
    "        outpath = './atac_idr_peaks/' + '_'.join([strain, treatment]) + '_peaks.tsv'\n",
    "        !cp $idrDirectory/$p $outpath\n",
    "outFile.close()\n",
    "\n",
    "\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 114,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "makeMultiWigHub.pl signals_atac mm10 -force -d ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180218-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180305-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep2 ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-rep1 ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06-rep2 -fragLength 150\n",
      "\n",
      "\tOnce finished, you will want to upload the following hub URL:\n",
      "\t\thttp://homer.ucsd.edu/hubs//signals_atac/hub.txt\n",
      "\n",
      "\tIf loading to the Wash U Epigenome Browser, use:\n",
      "\t\thttp://homer.ucsd.edu/hubs//signals_atac/washU.hub.txt\n",
      "\n",
      "\tOverwriting contents in /homer_data/www/html/hubs//signals_atac\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_GL456350_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr7_GL456219_random\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL23-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_GL456350_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584298_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_TNFa-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tGenerating bedGraph for chrY_JH584301_random\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_Veh-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_GL456350_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr7_GL456219_random\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584293_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL13-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL1B-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL4-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL6-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584293_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IFNg-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584293_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_TGFB-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tGenerating bedGraph for chrY_JH584300_random\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180218-rep1/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180218-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr1_GL456210_random\n",
      "\tGenerating bedGraph for chr1_GL456211_random\n",
      "\tGenerating bedGraph for chr1_GL456212_random\n",
      "\tGenerating bedGraph for chr1_GL456221_random\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr4_GL456216_random\n",
      "\tGenerating bedGraph for chr4_JH584292_random\n",
      "\tGenerating bedGraph for chr4_JH584295_random\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr5_GL456354_random\n",
      "\tGenerating bedGraph for chr5_JH584296_random\n",
      "\tGenerating bedGraph for chr5_JH584297_random\n",
      "\tGenerating bedGraph for chr5_JH584299_random\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrUn_GL456239\n",
      "\tGenerating bedGraph for chrUn_GL456359\n",
      "\tGenerating bedGraph for chrUn_GL456360\n",
      "\tGenerating bedGraph for chrUn_GL456366\n",
      "\tGenerating bedGraph for chrUn_GL456367\n",
      "\tGenerating bedGraph for chrUn_GL456368\n",
      "\tGenerating bedGraph for chrUn_GL456370\n",
      "\tGenerating bedGraph for chrUn_GL456372\n",
      "\tGenerating bedGraph for chrUn_GL456378\n",
      "\tGenerating bedGraph for chrUn_GL456379\n",
      "\tGenerating bedGraph for chrUn_GL456381\n",
      "\tGenerating bedGraph for chrUn_GL456382\n",
      "\tGenerating bedGraph for chrUn_GL456383\n",
      "\tGenerating bedGraph for chrUn_GL456385\n",
      "\tGenerating bedGraph for chrUn_GL456387\n",
      "\tGenerating bedGraph for chrUn_GL456389\n",
      "\tGenerating bedGraph for chrUn_GL456390\n",
      "\tGenerating bedGraph for chrUn_GL456392\n",
      "\tGenerating bedGraph for chrUn_GL456393\n",
      "\tGenerating bedGraph for chrUn_GL456394\n",
      "\tGenerating bedGraph for chrUn_GL456396\n",
      "\tGenerating bedGraph for chrUn_JH584304\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrX_GL456233_random\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180305-rep2/C57Bl6_BMDM_ATAC_IL5-24h_GJF_l20180305-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep1/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep1/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep2/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep2/C57Bl6_BMDM_ATAC_Veh_Nagy_18-01-16-rep2.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-rep1/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-rep1.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-rep1/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-rep1.ucsc.bigWig\n",
      "\n",
      "\tVisualization fragment length = 150\n",
      "\tOutput file: ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06-rep2/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06-rep2.ucsc.bigWig\n",
      "\tNo need to remove tags to get desired file size\n",
      "\tGenerating bedGraph for chr1\n",
      "\tGenerating bedGraph for chr10\n",
      "\tGenerating bedGraph for chr11\n",
      "\tGenerating bedGraph for chr12\n",
      "\tGenerating bedGraph for chr13\n",
      "\tGenerating bedGraph for chr14\n",
      "\tGenerating bedGraph for chr15\n",
      "\tGenerating bedGraph for chr16\n",
      "\tGenerating bedGraph for chr17\n",
      "\tGenerating bedGraph for chr18\n",
      "\tGenerating bedGraph for chr19\n",
      "\tGenerating bedGraph for chr2\n",
      "\tGenerating bedGraph for chr3\n",
      "\tGenerating bedGraph for chr4\n",
      "\tGenerating bedGraph for chr5\n",
      "\tGenerating bedGraph for chr6\n",
      "\tGenerating bedGraph for chr7\n",
      "\tGenerating bedGraph for chr8\n",
      "\tGenerating bedGraph for chr9\n",
      "\tGenerating bedGraph for chrX\n",
      "\tGenerating bedGraph for chrY\n",
      "\tCreating bigWig from bedGraph ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06-rep2/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06-rep2.ucsc.bigWig\n",
      "\n",
      "\tAll finished: you will want to upload the following hub URL:\n",
      "\t\thttp://homer.ucsd.edu/hubs//signals_atac/hub.txt\n",
      "\n",
      "\tIf loading to the Wash U Epigenome Browser, use:\n",
      "\t\thttp://homer.ucsd.edu/hubs//signals_atac/washU.hub.txt\n",
      "\n",
      "\n",
      "\tTo edit track settings, edit files in:\n",
      "\t\t/homer_data/www/html/hubs//signals_atac\n",
      "\n"
     ]
    }
   ],
   "source": [
    "# create track hub containing best samples\n",
    "tagDirectories = []\n",
    "# for key in sorted(treatment_bestIDR_dict.keys()):\n",
    "for key in treatment_bestIDR_dict.keys():\n",
    "    p = treatment_bestIDR_dict[key]\n",
    "    tokens = p.split('_')\n",
    "    strain = tokens[0]\n",
    "    factor = tokens[1]\n",
    "    treatment = tokens[2]\n",
    "    sample1 = simpleName_originalName_dict['_'.join(tokens[:4])]\n",
    "    sample2 = simpleName_originalName_dict['_'.join(tokens[5:9])]\n",
    "    tagDirectories.append(sample1)\n",
    "    tagDirectories.append(sample2)\n",
    "tagDirectories = ['./tag_directories_atac/'+x for x in tagDirectories]\n",
    "tagDirString = ' '.join(tagDirectories)\n",
    "! echo makeMultiWigHub.pl signals_atac mm10 -force -d $tagDirString -fragLength 150\n",
    "! makeMultiWigHub.pl signals_atac mm10 -force -fragLength 150 -d $tagDirString"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Merge Peak Files"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [],
   "source": [
    "target_peak_size = 75\n",
    "\n",
    "if not os.path.isdir('./resized_peak_files'):\n",
    "    os.mkdir('./resized_peak_files')\n",
    "else:\n",
    "    for rpf in os.listdir('./resized_peak_files'):\n",
    "        os.remove('./resized_peak_files/' + rpf)\n",
    "\n",
    "for pf in os.listdir('./atac_idr_peaks/'):\n",
    "    current_peak_frame = pd.read_csv('./atac_idr_peaks/' + pf, sep='\\t' )\n",
    "    peakCenters = (current_peak_frame['start'] + current_peak_frame['end']) /2\n",
    "    int_peakCenters = np.ceil(peakCenters).astype(int)\n",
    "    new_starts = int_peakCenters - int(target_peak_size/2)\n",
    "    new_ends = int_peakCenters + int(target_peak_size/2)\n",
    "    current_peak_frame['start'] = new_starts\n",
    "    current_peak_frame['end'] = new_ends\n",
    "    current_peak_frame.to_csv('./resized_peak_files/' + pf, sep='\\t', index=False)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "%%capture\n",
    "! mergePeaks -d given -venn venn.txt ./resized_peak_files/* > ./merged_atac_peaks.tsv"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/jtao/software/anaconda3/lib/python3.5/site-packages/ipykernel/__main__.py:16: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n",
      "/home/jtao/software/anaconda3/lib/python3.5/site-packages/ipykernel/__main__.py:17: SettingWithCopyWarning: \n",
      "A value is trying to be set on a copy of a slice from a DataFrame.\n",
      "Try using .loc[row_indexer,col_indexer] = value instead\n",
      "\n",
      "See the caveats in the documentation: http://pandas.pydata.org/pandas-docs/stable/indexing.html#indexing-view-versus-copy\n"
     ]
    }
   ],
   "source": [
    "merged_frame = pd.read_csv('./merged_atac_peaks.tsv', sep='\\t')\n",
    "\n",
    "# filter away peaks in unused chromsomes\n",
    "filtered_frame = merged_frame[\n",
    "             ~(merged_frame['chr'].str.contains('chrY')) & \n",
    "             ~(merged_frame['chr'].str.contains('chrM')) &\n",
    "             ~(merged_frame['chr'].str.contains('random')) &\n",
    "             ~(merged_frame['chr'].str.contains('Un'))]\n",
    "\n",
    "# resize peaks\n",
    "target_peak_size = 150\n",
    "peakCenters = (filtered_frame['start'] + filtered_frame['end']) /2\n",
    "int_peakCenters = np.ceil(peakCenters).astype(int)\n",
    "new_starts = int_peakCenters - int(target_peak_size/2)\n",
    "new_ends = int_peakCenters + int(target_peak_size/2)\n",
    "filtered_frame['start'] = new_starts\n",
    "filtered_frame['end'] = new_ends\n",
    "filtered_frame.to_csv('./merged_atac_peaks_filtered_resized.tsv', sep='\\t', index=False)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Annotate peaks"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### ATAC"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\n",
      "\tPeak file = ./merged_atac_peaks_filtered_resized.tsv\n",
      "\tGenome = mm10\n",
      "\tOrganism = mouse\n",
      "\tTag Directories:\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-1h_SD_SD340/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-1h_SD_SD341/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-1h_SD_SD336/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-1h_SD_SD337/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-and-16-09-15/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_PamCSK-1h_SD_SD342/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_PamCSK-1h_SD_SD343/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_R848-1h_SD_SD344/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_R848-1h_SD_SD345/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFbeta-1h_SD_SD338/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFbeta-1h_SD_SD339/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_BC_16-02-11-and-16-09-15/\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_BC_16-05-06/\n",
      "\tPeak/BED file conversion summary:\n",
      "\t\tBED/Header formatted lines: 0\n",
      "\t\tpeakfile formatted lines: 54859\n",
      "\t\tDuplicated Peak IDs: 0\n",
      "\n",
      "\tPeak File Statistics:\n",
      "\t\tTotal Peaks: 54859\n",
      "\t\tRedundant Peak IDs: 0\n",
      "\t\tPeaks lacking information: 0 (need at least 5 columns per peak)\n",
      "\t\tPeaks with misformatted coordinates: 0 (should be integer)\n",
      "\t\tPeaks with misformatted strand: 0 (should be either +/- or 0/1)\n",
      "\n",
      "\tPeak file looks good!\n",
      "\n",
      "\tReading Positions...\n",
      "\t-----------------------\n",
      "\tFinding Closest TSS...\n",
      "\tAnnotating:....................\n",
      "\t\tAnnotation\tNumber of peaks\tTotal size (bp)\tLog2 Enrichment\n",
      "\t\t3UTR\t508.0\t19668322\t0.309\n",
      "\t\tmiRNA\t2.0\t20053\t2.258\n",
      "\t\tncRNA\t157.0\t2893366\t1.380\n",
      "\t\tTTS\t797.0\t26128255\t0.549\n",
      "\t\tpseudo\t6.0\t509738\t-0.825\n",
      "\t\tExon\t861.0\t33217203\t0.314\n",
      "\t\tIntron\t21863.0\t926318212\t0.178\n",
      "\t\tIntergenic\t18123.0\t1591257167\t-0.873\n",
      "\t\tPromoter\t11968.0\t28309367\t4.341\n",
      "\t\t5UTR\t559.0\t2077761\t3.689\n",
      "\t\tsnoRNA\t0.0\t19\t-15.743\n",
      "\t\trRNA\t15.0\t5631\t6.997\n",
      "\tNOTE: If this part takes more than 2 minutes, there is a good chance\n",
      "\t\tyour machine ran out of memory: consider hitting ctrl+C and rerunning\n",
      "\t\tthe command with \"-noann\"\n",
      "\tTo capture annotation stats in a file, use \"-annStats <filename>\" next time\n",
      "\tAnnotating:....................\n",
      "\t\tAnnotation\tNumber of peaks\tTotal size (bp)\tLog2 Enrichment\n",
      "\t\t3UTR\t508.0\t19668322\t0.309\n",
      "\t\tOther\t84.0\t7166306\t-0.831\n",
      "\t\tRC?\t0.0\t10979\t-15.743\n",
      "\t\tRNA\t1.0\t114021\t-1.249\n",
      "\t\tmiRNA\t2.0\t20053\t2.258\n",
      "\t\tncRNA\t157.0\t2893366\t1.380\n",
      "\t\tTTS\t797.0\t26128255\t0.549\n",
      "\t\tLINE\t1601.0\t521357097\t-2.763\n",
      "\t\tLINE?\t0.0\t8168\t-15.743\n",
      "\t\tsrpRNA\t1.0\t43388\t0.145\n",
      "\t\tSINE\t1573.0\t194261631\t-1.364\n",
      "\t\tRC\t0.0\t65909\t-15.743\n",
      "\t\ttRNA\t44.0\t266920\t2.983\n",
      "\t\tDNA?\t1.0\t142594\t-1.572\n",
      "\t\tpseudo\t6.0\t509738\t-0.825\n",
      "\t\tDNA\t316.0\t28414247\t-0.906\n",
      "\t\tExon\t861.0\t33217203\t0.314\n",
      "\t\tIntron\t17224.0\t589127896\t0.488\n",
      "\t\tIntergenic\t13924.0\t801077083\t-0.262\n",
      "\t\tPromoter\t11965.0\t28309367\t4.342\n",
      "\t\t5UTR\t559.0\t2077761\t3.690\n",
      "\t\tsnoRNA\t0.0\t19\t-15.743\n",
      "\t\tLTR?\t4.0\t193659\t-0.013\n",
      "\t\tscRNA\t5.0\t579110\t-1.272\n",
      "\t\tCpG-Island\t1727.0\t3345642\t4.630\n",
      "\t\tLow_complexity\t132.0\t18533957\t-1.549\n",
      "\t\tLTR\t3164.0\t293374785\t-0.951\n",
      "\t\tSimple_repeat\t121.0\t55384339\t-3.254\n",
      "\t\tsnRNA\t4.0\t237355\t-0.307\n",
      "\t\tUnknown\t7.0\t1251155\t-1.898\n",
      "\t\tSINE?\t0.0\t29758\t-15.743\n",
      "\t\tSatellite\t36.0\t3706654\t-1.102\n",
      "\t\trRNA\t35.0\t165655\t3.341\n",
      "\tCounting Tags in Peaks from each directory...\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-1h_SD_SD340/ : 2.73042612122218\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-1h_SD_SD341/ : 2.58331647719332\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-1h_SD_SD336/ : 2.83916042619205\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-1h_SD_SD337/ : 3.63732918192829\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-and-16-09-15/ : 2.06387401122376\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06/ : 1.69756258870826\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_PamCSK-1h_SD_SD342/ : 3.84288000799319\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_PamCSK-1h_SD_SD343/ : 2.57015891292559\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_R848-1h_SD_SD344/ : 2.89536917549441\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_R848-1h_SD_SD345/ : 3.50382845816481\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFbeta-1h_SD_SD338/ : 4.06096647753392\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFbeta-1h_SD_SD339/ : 2.34845369589075\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_BC_16-02-11-and-16-09-15/ : 2.90393015002574\n",
      "\tRatio for ./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_BC_16-05-06/ : 1.40978920972715\n",
      "\tOrganism: mouse\n",
      "\tLoading Gene Informaiton...\n",
      "\tOutputing Annotation File...\n",
      "\tDone annotating peaks file\n",
      "\n"
     ]
    }
   ],
   "source": [
    "! annotatePeaks.pl ./merged_atac_peaks_filtered_resized.tsv mm10 -d ./tag_directories_atac/*/ > ./annotated_atac_peaks.tsv"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### H3k27Ac"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\n",
      "\tPeak file = ./merged_atac_peaks_filtered_resized.tsv\n",
      "\tGenome = mm10\n",
      "\tOrganism = mouse\n",
      "\tMaximum count per bp will be set to 1\n",
      "\tPeak Region set to 500\n",
      "\tTag Directories:\n",
      "\t\t./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_IL4-24h_MAH_l20171004/\n",
      "\t\t./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_IL4-24h_MAH_l20171129/\n",
      "\t\t./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27Ac_KLA-1h_BC_16-04-15-rep1/\n",
      "\t\t./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27Ac_KLA-1h_BC_16-04-15-rep2/\n",
      "\t\t./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_Veh_MAH_l20171004/\n",
      "\t\t./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_Veh_MAH_l20171121/\n",
      "\tPeak/BED file conversion summary:\n",
      "\t\tBED/Header formatted lines: 0\n",
      "\t\tpeakfile formatted lines: 54771\n",
      "\t\tDuplicated Peak IDs: 0\n",
      "\n",
      "\tPeak File Statistics:\n",
      "\t\tTotal Peaks: 54771\n",
      "\t\tRedundant Peak IDs: 0\n",
      "\t\tPeaks lacking information: 0 (need at least 5 columns per peak)\n",
      "\t\tPeaks with misformatted coordinates: 0 (should be integer)\n",
      "\t\tPeaks with misformatted strand: 0 (should be either +/- or 0/1)\n",
      "\n",
      "\tPeak file looks good!\n",
      "\n",
      "\tResizing peaks...\n",
      "\tReading Positions...\n",
      "\t-----------------------\n",
      "\tFinding Closest TSS...\n",
      "\tAnnotating:....................\n",
      "\t\tAnnotation\tNumber of peaks\tTotal size (bp)\tLog2 Enrichment\n",
      "\t\t3UTR\t501.0\t19668322\t0.291\n",
      "\t\tmiRNA\t2.0\t20053\t2.260\n",
      "\t\tncRNA\t158.0\t2893366\t1.391\n",
      "\t\tTTS\t708.0\t26128255\t0.380\n",
      "\t\tpseudo\t10.0\t509738\t-0.086\n",
      "\t\tExon\t867.0\t33217203\t0.326\n",
      "\t\tIntron\t21954.0\t926318212\t0.187\n",
      "\t\tIntergenic\t18581.0\t1591257167\t-0.834\n",
      "\t\tPromoter\t11506.0\t28309367\t4.287\n",
      "\t\t5UTR\t472.0\t2077761\t3.448\n",
      "\t\tsnoRNA\t0.0\t19\t-15.741\n",
      "\t\trRNA\t12.0\t5631\t6.677\n",
      "\tNOTE: If this part takes more than 2 minutes, there is a good chance\n",
      "\t\tyour machine ran out of memory: consider hitting ctrl+C and rerunning\n",
      "\t\tthe command with \"-noann\"\n",
      "\tTo capture annotation stats in a file, use \"-annStats <filename>\" next time\n",
      "\tAnnotating:....................\n",
      "\t\tAnnotation\tNumber of peaks\tTotal size (bp)\tLog2 Enrichment\n",
      "\t\t3UTR\t501.0\t19668322\t0.292\n",
      "\t\tOther\t98.0\t7166306\t-0.606\n",
      "\t\tRC?\t0.0\t10979\t-15.741\n",
      "\t\tRNA\t1.0\t114021\t-1.247\n",
      "\t\tmiRNA\t2.0\t20053\t2.261\n",
      "\t\tncRNA\t157.0\t2893366\t1.383\n",
      "\t\tTTS\t708.0\t26128255\t0.381\n",
      "\t\tLINE\t1755.0\t521357097\t-2.628\n",
      "\t\tLINE?\t0.0\t8168\t-15.741\n",
      "\t\tsrpRNA\t1.0\t43388\t0.147\n",
      "\t\tSINE\t1502.0\t194261631\t-1.429\n",
      "\t\tRC\t1.0\t65909\t-0.456\n",
      "\t\ttRNA\t28.0\t266920\t2.334\n",
      "\t\tDNA?\t1.0\t142594\t-1.569\n",
      "\t\tpseudo\t10.0\t509738\t-0.085\n",
      "\t\tDNA\t344.0\t28414247\t-0.782\n",
      "\t\tExon\t867.0\t33217203\t0.327\n",
      "\t\tIntron\t17126.0\t589127896\t0.482\n",
      "\t\tIntergenic\t13781.0\t801077083\t-0.275\n",
      "\t\tPromoter\t11505.0\t28309367\t4.287\n",
      "\t\t5UTR\t472.0\t2077761\t3.448\n",
      "\t\tsnoRNA\t0.0\t19\t-15.741\n",
      "\t\tLTR?\t4.0\t193659\t-0.011\n",
      "\t\tscRNA\t2.0\t579110\t-2.591\n",
      "\t\tCpG-Island\t1577.0\t3345642\t4.501\n",
      "\t\tLow_complexity\t133.0\t18533957\t-1.536\n",
      "\t\tLTR\t3945.0\t293374785\t-0.630\n",
      "\t\tSimple_repeat\t148.0\t55384339\t-2.961\n",
      "\t\tsnRNA\t1.0\t237355\t-2.304\n",
      "\t\tUnknown\t11.0\t1251155\t-1.243\n",
      "\t\tSINE?\t0.0\t29758\t-15.741\n",
      "\t\tSatellite\t57.0\t3706654\t-0.437\n",
      "\t\trRNA\t33.0\t165655\t3.259\n",
      "\tCounting Tags in Peaks from each directory...\n",
      "\tRatio for ./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_IL4-24h_MAH_l20171004/ : 0.925404100835732\n",
      "\tRatio for ./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_IL4-24h_MAH_l20171129/ : 1.04327929390023\n",
      "\tRatio for ./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27Ac_KLA-1h_BC_16-04-15-rep1/ : 0.592984718012937\n",
      "\tRatio for ./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27Ac_KLA-1h_BC_16-04-15-rep2/ : 0.773312012605604\n",
      "\tRatio for ./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_Veh_MAH_l20171004/ : 0.832553646843065\n",
      "\tRatio for ./tag_directories_enhancer_marks/C57Bl6_BMDM_ChIP_H3K27ac_Veh_MAH_l20171121/ : 0.810125663452412\n",
      "\tOrganism: mouse\n",
      "\tLoading Gene Informaiton...\n",
      "\tOutputing Annotation File...\n",
      "\tDone annotating peaks file\n",
      "\n"
     ]
    }
   ],
   "source": [
    "!annotatePeaks.pl ./merged_atac_peaks_filtered_resized.tsv mm10 -size 500 -d ./tag_directories_enhancer_marks/*/ > ./merged_atac_annotated_h3k27ac_peaks.tsv\n",
    "!annotatePeaks.pl ./merged_atac_peaks_filtered_resized.tsv mm10 -pc 1 -size 500 -d ./tag_directories_enhancer_marks/*/ > ./merged_atac_annotated_h3k27ac_nodups_peaks.tsv\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 58,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Finished reading merged peak file...\n",
      "Integrating scores for c57bl6_ifng-1h\n",
      "Integrating scores for c57bl6_il4-1h\n",
      "Integrating scores for c57bl6_kla-1h\n",
      "Integrating scores for c57bl6_pamcsk-1h\n",
      "Integrating scores for c57bl6_r848-1h\n",
      "Integrating scores for c57bl6_tgfbeta-1h\n",
      "Integrating scores for c57bl6_veh\n"
     ]
    }
   ],
   "source": [
    "! makeSummaryFile.py ./merged_atac_peaks_filtered_resized.tsv ./group_atac_summary.tsv ./resized_peak_files/*"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 61,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "# read in peak data data\n",
    "summary_frame = pd.read_csv('./group_atac_summary.tsv' , sep='\\t')\n",
    "summary_frame = summary_frame.fillna('0')\n",
    "for col in summary_frame.columns[5:]:\n",
    "    floatValues = []\n",
    "    for val in summary_frame[col].values.astype(str):\n",
    "        if ',' in val:\n",
    "            maxVal = np.mean([float(x) for x in val.split(',')])\n",
    "            floatValues.append(maxVal)\n",
    "        else:\n",
    "            floatValues.append(float(val))\n",
    "    summary_frame[col] = floatValues\n",
    "summary_frame.index = summary_frame['ID'].values\n",
    "\n",
    "# remove peaks in unknown/random chromosomes\n",
    "summary_frame = summary_frame[~summary_frame['chr'].str.contains('random')]\n",
    "summary_frame = summary_frame[~summary_frame['chr'].str.contains('Un')]\n",
    "\n",
    "\n",
    "_factors = sorted(list(set([x.split('_')[1] for x in summary_frame.columns if '_' in x])))\n",
    "summary_frame.to_pickle('summary_frame.pickle')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Calculate Differential ATAC-seq peaks"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 82,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\n",
      "\tPeak file = ./merged_atac_peaks_filtered_resized.tsv\n",
      "\tGenome = mm10\n",
      "\tOrganism = mouse\n",
      "\tWill NOT normalize tag counts\n",
      "\tTag Directories:\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_BC_16-02-11-and-16-09-15\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_Veh_BC_16-05-06\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-1h_SD_SD340\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IFNg-1h_SD_SD341\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-1h_SD_SD336\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_IL4-1h_SD_SD337\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-02-11-and-16-09-15\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_KLA-1h_BC_16-05-06\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_PamCSK-1h_SD_SD342\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_PamCSK-1h_SD_SD343\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_R848-1h_SD_SD344\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_R848-1h_SD_SD345\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFbeta-1h_SD_SD338\n",
      "\t\t./tag_directories_atac/C57Bl6_BMDM_ATAC_TGFbeta-1h_SD_SD339\n",
      "\tPeak/BED file conversion summary:\n",
      "\t\tBED/Header formatted lines: 0\n",
      "\t\tpeakfile formatted lines: 54859\n",
      "\t\tDuplicated Peak IDs: 0\n",
      "\n",
      "\tPeak File Statistics:\n",
      "\t\tTotal Peaks: 54859\n",
      "\t\tRedundant Peak IDs: 0\n",
      "\t\tPeaks lacking information: 0 (need at least 5 columns per peak)\n",
      "\t\tPeaks with misformatted coordinates: 0 (should be integer)\n",
      "\t\tPeaks with misformatted strand: 0 (should be either +/- or 0/1)\n",
      "\n",
      "\tPeak file looks good!\n",
      "\n",
      "\tReading Positions...\n",
      "\t-----------------------\n",
      "\tFinding Closest TSS...\n",
      "\tAnnotating:....................\n",
      "\t\tAnnotation\tNumber of peaks\tTotal size (bp)\tLog2 Enrichment\n",
      "\t\t3UTR\t508.0\t19668322\t0.309\n",
      "\t\tmiRNA\t2.0\t20053\t2.258\n",
      "\t\tncRNA\t157.0\t2893366\t1.380\n",
      "\t\tTTS\t797.0\t26128255\t0.549\n",
      "\t\tpseudo\t6.0\t509738\t-0.825\n",
      "\t\tExon\t861.0\t33217203\t0.314\n",
      "\t\tIntron\t21863.0\t926318212\t0.178\n",
      "\t\tIntergenic\t18123.0\t1591257167\t-0.873\n",
      "\t\tPromoter\t11968.0\t28309367\t4.341\n",
      "\t\t5UTR\t559.0\t2077761\t3.689\n",
      "\t\tsnoRNA\t0.0\t19\t-15.743\n",
      "\t\trRNA\t15.0\t5631\t6.997\n",
      "\tNOTE: If this part takes more than 2 minutes, there is a good chance\n",
      "\t\tyour machine ran out of memory: consider hitting ctrl+C and rerunning\n",
      "\t\tthe command with \"-noann\"\n",
      "\tTo capture annotation stats in a file, use \"-annStats <filename>\" next time\n",
      "\tAnnotating:....................\n",
      "\t\tAnnotation\tNumber of peaks\tTotal size (bp)\tLog2 Enrichment\n",
      "\t\t3UTR\t508.0\t19668322\t0.309\n",
      "\t\tOther\t84.0\t7166306\t-0.831\n",
      "\t\tRC?\t0.0\t10979\t-15.743\n",
      "\t\tRNA\t1.0\t114021\t-1.249\n",
      "\t\tmiRNA\t2.0\t20053\t2.258\n",
      "\t\tncRNA\t157.0\t2893366\t1.380\n",
      "\t\tTTS\t797.0\t26128255\t0.549\n",
      "\t\tLINE\t1601.0\t521357097\t-2.763\n",
      "\t\tLINE?\t0.0\t8168\t-15.743\n",
      "\t\tsrpRNA\t1.0\t43388\t0.145\n",
      "\t\tSINE\t1573.0\t194261631\t-1.364\n",
      "\t\tRC\t0.0\t65909\t-15.743\n",
      "\t\ttRNA\t44.0\t266920\t2.983\n",
      "\t\tDNA?\t1.0\t142594\t-1.572\n",
      "\t\tpseudo\t6.0\t509738\t-0.825\n",
      "\t\tDNA\t316.0\t28414247\t-0.906\n",
      "\t\tExon\t861.0\t33217203\t0.314\n",
      "\t\tIntron\t17224.0\t589127896\t0.488\n",
      "\t\tIntergenic\t13924.0\t801077083\t-0.262\n",
      "\t\tPromoter\t11965.0\t28309367\t4.342\n",
      "\t\t5UTR\t559.0\t2077761\t3.690\n",
      "\t\tsnoRNA\t0.0\t19\t-15.743\n",
      "\t\tLTR?\t4.0\t193659\t-0.013\n",
      "\t\tscRNA\t5.0\t579110\t-1.272\n",
      "\t\tCpG-Island\t1727.0\t3345642\t4.630\n",
      "\t\tLow_complexity\t132.0\t18533957\t-1.549\n",
      "\t\tLTR\t3164.0\t293374785\t-0.951\n",
      "\t\tSimple_repeat\t121.0\t55384339\t-3.254\n",
      "\t\tsnRNA\t4.0\t237355\t-0.307\n",
      "\t\tUnknown\t7.0\t1251155\t-1.898\n",
      "\t\tSINE?\t0.0\t29758\t-15.743\n",
      "\t\tSatellite\t36.0\t3706654\t-1.102\n",
      "\t\trRNA\t35.0\t165655\t3.341\n",
      "\tCounting Tags in Peaks from each directory...\n",
      "\tOrganism: mouse\n",
      "\tLoading Gene Informaiton...\n",
      "\tOutputing Annotation File...\n",
      "\tDone annotating peaks file\n",
      "\n"
     ]
    }
   ],
   "source": [
    "tag_dirs = sorted(os.listdir('./tag_directories_atac/'))\n",
    "treated_dirs = ' '.join(['./tag_directories_atac/' + x for x in tag_dirs if not '_Veh_' in x])\n",
    "veh_dirs = ' '.join(['./tag_directories_atac/' +x for x in tag_dirs if  '_Veh_' in x])\n",
    "! annotatePeaks.pl ./merged_atac_peaks_filtered_resized.tsv mm10 -raw -d $veh_dirs $treated_dirs > ./annotated_atac_peaks_raw.tsv"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 83,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\n",
      "\tDifferential Expression Program: edgeR\n",
      "\tAutodetecting input file format...\n",
      "\tUsing edgeR to calculate differential expression/enrichment...\n",
      "\tAutodetected annotatePeaks.pl file\n",
      "\tOutput Stats Veh vs. IFNg-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in IFNg-1h vs. Veh: 4219 (7.691%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in IFNg-1h vs. Veh: 5087 (9.273%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats Veh vs. IL4-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in IL4-1h vs. Veh: 2181 (3.976%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in IL4-1h vs. Veh: 2898 (5.283%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats Veh vs. KLA-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in KLA-1h vs. Veh: 1420 (2.588%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in KLA-1h vs. Veh: 366 (0.667%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats Veh vs. PamCSK-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in PamCSK-1h vs. Veh: 4991 (9.098%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in PamCSK-1h vs. Veh: 6137 (11.187%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats Veh vs. R848-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in R848-1h vs. Veh: 3314 (6.041%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in R848-1h vs. Veh: 4219 (7.691%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats Veh vs. TGFbeta-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in TGFbeta-1h vs. Veh: 2135 (3.892%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in TGFbeta-1h vs. Veh: 3412 (6.220%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IFNg-1h vs. IL4-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in IL4-1h vs. IFNg-1h: 47 (0.086%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in IL4-1h vs. IFNg-1h: 72 (0.131%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IFNg-1h vs. KLA-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in KLA-1h vs. IFNg-1h: 8034 (14.645%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in KLA-1h vs. IFNg-1h: 5979 (10.899%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IFNg-1h vs. PamCSK-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in PamCSK-1h vs. IFNg-1h: 648 (1.181%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in PamCSK-1h vs. IFNg-1h: 360 (0.656%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IFNg-1h vs. R848-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in R848-1h vs. IFNg-1h: 395 (0.720%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in R848-1h vs. IFNg-1h: 214 (0.390%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IFNg-1h vs. TGFbeta-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in TGFbeta-1h vs. IFNg-1h: 149 (0.272%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in TGFbeta-1h vs. IFNg-1h: 143 (0.261%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IL4-1h vs. KLA-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in KLA-1h vs. IL4-1h: 6013 (10.961%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in KLA-1h vs. IL4-1h: 4106 (7.485%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IL4-1h vs. PamCSK-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in PamCSK-1h vs. IL4-1h: 361 (0.658%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in PamCSK-1h vs. IL4-1h: 169 (0.308%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IL4-1h vs. R848-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in R848-1h vs. IL4-1h: 217 (0.396%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in R848-1h vs. IL4-1h: 73 (0.133%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats IL4-1h vs. TGFbeta-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in TGFbeta-1h vs. IL4-1h: 30 (0.055%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in TGFbeta-1h vs. IL4-1h: 22 (0.040%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats KLA-1h vs. PamCSK-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in PamCSK-1h vs. KLA-1h: 4371 (7.968%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in PamCSK-1h vs. KLA-1h: 5983 (10.906%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats KLA-1h vs. R848-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in R848-1h vs. KLA-1h: 2664 (4.856%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in R848-1h vs. KLA-1h: 4222 (7.696%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats KLA-1h vs. TGFbeta-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in TGFbeta-1h vs. KLA-1h: 3550 (6.471%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in TGFbeta-1h vs. KLA-1h: 5339 (9.732%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats PamCSK-1h vs. R848-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in R848-1h vs. PamCSK-1h: 0 (0.000%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in R848-1h vs. PamCSK-1h: 1 (0.002%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats PamCSK-1h vs. TGFbeta-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in TGFbeta-1h vs. PamCSK-1h: 76 (0.139%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in TGFbeta-1h vs. PamCSK-1h: 166 (0.303%) [log2fold<-1, FDR<0.05]\n",
      "\tOutput Stats R848-1h vs. TGFbeta-1h:\n",
      "\t\tTotal Genes: 54859\n",
      "\t\tTotal Up-regulated in TGFbeta-1h vs. R848-1h: 30 (0.055%) [log2fold>1, FDR<0.05]\n",
      "\t\tTotal Dn-regulated in TGFbeta-1h vs. R848-1h: 80 (0.146%) [log2fold<-1, FDR<0.05]\n",
      "\n"
     ]
    }
   ],
   "source": [
    "with open('./annotated_atac_peaks_raw.tsv') as f:\n",
    "    data = f.readline()\n",
    "conditions = [x.split('/')[2].split('_')[3] for x in data.split('\\t')[19:]]\n",
    "condition_string = ' '.join(conditions)\n",
    "!getDiffExpression.pl ./annotated_atac_peaks_raw.tsv $condition_string -AvsA > edgeR_atac_out.tsv"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Calculate Motif Scores"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 116,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "rm: cannot remove ‘./peak_sequences/*’: No such file or directory\n"
     ]
    }
   ],
   "source": [
    "%%bash\n",
    "if [ ! -d ./peak_sequences ] ;\n",
    "    then mkdir ./peak_sequences\n",
    "else\n",
    "    rm ./peak_sequences/*\n",
    "fi"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 117,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "\n",
      "\tConverted 54771 peaks total\n",
      "\n"
     ]
    }
   ],
   "source": [
    "%%bash\n",
    "# extract sequences for analysis\n",
    "pos2bed.pl ./merged_atac_peaks_filtered_resized.tsv > ./tmp\n",
    "tail -n +2 ./tmp > ./merged_atac_peaks_filtered_resized.bed\n",
    "rm tmp"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 119,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "reading genome mm10\r\n"
     ]
    }
   ],
   "source": [
    "!/gpfs/data01/glasslab/home/jtao/code/tba/model_training/extract_sequences.py ./merged_atac_peaks_filtered_resized.bed mm10 ./merged_atac_peaks_filtered_resized.fasta"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Generate background"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 127,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "filtering out: chrM chrY\n",
      "reading genome mm10\n",
      "done reading genome\n",
      "0 0\n",
      "target GC: 0.40041037960885784 background GC: 0.39855913302169993 target length: 201 numTargetPositions 5478 backgroundPositions 5478\n",
      "0 0\n",
      "target GC: 0.44257628758014855 background GC: 0.4396666889620827 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.4657741540813229 background GC: 0.46176721013342376 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.48472177321156007 background GC: 0.48033902349514895 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.5030326273477757 background GC: 0.49830795568140956 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.5227505413637907 background GC: 0.5137541871769331 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.5465697306266066 background GC: 0.5354588133634863 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.5819506101089758 background GC: 0.5693114500421593 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.6413178183105089 background GC: 0.6310873373259707 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n",
      "0 0\n",
      "target GC: 0.728605491021659 background GC: 0.7213405474196577 target length: 201 numTargetPositions 5477 backgroundPositions 5477\n"
     ]
    }
   ],
   "source": [
    "!/home/jtao/code/tba/model_training/generate_background_coordinates.py ./merged_atac_peaks_filtered_resized.bed mm10 ./"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### All Motif Scores"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 122,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Arid3a calculation time: 6.360261678695679\n",
      "Ahr::Arnt calculation time: 7.27443528175354\n",
      "BARHL2 calculation time: 9.730804920196533\n",
      "AP-2_2_merged calculation time: 10.778937578201294\n",
      "Dux calculation time: 8.009639263153076\n",
      "Arid3b calculation time: 11.931458950042725\n",
      "CEBP-related_2_merged calculation time: 11.283847332000732\n",
      "CEBP-related_1_merged calculation time: 12.583008527755737\n",
      "CEBPA calculation time: 12.362027168273926\n",
      "Arid5a calculation time: 13.410557270050049\n",
      "Bcl6 calculation time: 12.944523572921753\n",
      "DMRT3 calculation time: 11.673742532730103\n",
      "E2F-related_1_merged calculation time: 11.308987617492676\n",
      "AP-2_1_merged calculation time: 14.571696281433105\n",
      "Bach1::Mafk calculation time: 13.9734947681427\n",
      "CREB1 calculation time: 12.70511245727539\n",
      "E2F1 calculation time: 11.48635458946228\n",
      "CP2-related_1_merged calculation time: 13.705713748931885\n",
      "BCL6B calculation time: 14.928110599517822\n",
      "EBF1 calculation time: 12.57084345817566\n",
      "ATF4 calculation time: 16.7510883808136\n",
      "Ddit3::Cebpa calculation time: 14.101332664489746\n",
      "CREB-related_1_merged calculation time: 14.8646879196167\n",
      "CENPB calculation time: 15.37636661529541\n",
      "EGR1 calculation time: 13.059547424316406\n",
      "CTCF calculation time: 17.744228839874268\n",
      "E2F-related_3_merged calculation time: 17.296658039093018\n",
      "Brachyury-related_1_merged calculation time: 20.291057348251343\n",
      "FOXH1 calculation time: 11.59627890586853\n",
      "Ets-related_2_merged calculation time: 12.02521562576294\n",
      "Ets-related_1_merged calculation time: 13.279185056686401\n",
      "E2F-related_2_merged calculation time: 21.320881128311157\n",
      "Gabpa calculation time: 10.505650043487549\n",
      "Foxq1 calculation time: 11.516088962554932\n",
      "GLI2 calculation time: 11.234703540802002\n",
      "Gfi1b calculation time: 10.585873126983643\n",
      "GCM_1_merged calculation time: 12.224518775939941\n",
      "HD-CUT_1_merged calculation time: 10.820809841156006\n",
      "Factors_1_merged calculation time: 15.672771215438843\n",
      "Foxd3 calculation time: 14.4249746799469\n",
      "HLTF calculation time: 11.713331460952759\n",
      "HD-CUT_2_merged calculation time: 12.417039632797241\n",
      "HMBOX1 calculation time: 12.99198055267334\n",
      "HOX-related_1_merged calculation time: 10.304387331008911\n",
      "Gfi1 calculation time: 15.236733675003052\n",
      "GATA-type_1_merged calculation time: 16.810736894607544\n",
      "HOXA5 calculation time: 7.992169380187988\n",
      "GATA1::TAL1 calculation time: 16.760565996170044\n",
      "GMEB2 calculation time: 16.304394483566284\n",
      "HNF4G calculation time: 14.9735267162323\n",
      "HOX-related_3_merged calculation time: 12.377613306045532\n",
      "Forkhead_1_merged calculation time: 20.468371152877808\n",
      "EWSR1-FLI1 calculation time: 26.291455507278442\n",
      "HINFP calculation time: 16.895772457122803\n",
      "Hairy-related_1_merged calculation time: 10.571413040161133\n",
      "HSF_1_merged calculation time: 12.30671739578247\n",
      "Gmeb1 calculation time: 20.6582612991333\n",
      "HOX-related_4_merged calculation time: 15.347577095031738\n",
      "Hand1::Tcf3 calculation time: 12.314773321151733\n",
      "INSM1 calculation time: 11.006110668182373\n",
      "Hes2 calculation time: 11.993550777435303\n",
      "Jun-related_2_merged calculation time: 9.330763339996338\n",
      "Jun-related_1_merged calculation time: 9.610368490219116\n",
      "MAFG::NFE2L1 calculation time: 6.971141815185547\n",
      "MZF1 calculation time: 8.032430410385132\n",
      "Hoxd8 calculation time: 14.402150392532349\n",
      "Hnf4a calculation time: 14.850180625915527\n",
      "HOX-related_2_merged calculation time: 21.338649034500122\n",
      "Klf12 calculation time: 13.205886125564575\n",
      "Lhx3 calculation time: 11.854658126831055\n",
      "More_3_merged calculation time: 9.34225082397461\n",
      "IRF2 calculation time: 17.473578214645386\n",
      "MZF1_var.2 calculation time: 11.483937740325928\n",
      "MTF1 calculation time: 13.04705286026001\n",
      "Interferon-regulatory_1_merged calculation time: 17.10037851333618\n",
      "LIN54 calculation time: 17.10702919960022\n",
      "Mecom calculation time: 14.140864372253418\n",
      "MyoD_1_merged calculation time: 10.662601470947266\n",
      "IRF1 calculation time: 21.6448814868927\n",
      "More_1_merged calculation time: 14.845658779144287\n",
      "MAFG calculation time: 17.60188603401184\n",
      "MAF::NFE2 calculation time: 18.23789095878601\n",
      "More_4_merged calculation time: 14.202317953109741\n",
      "Maf-related_1_merged calculation time: 17.082201957702637\n",
      "Myod1 calculation time: 12.759938716888428\n",
      "Myb calculation time: 14.146711349487305\n",
      "NF-kappaB-related_1_merged calculation time: 12.628432512283325\n",
      "NFIL3 calculation time: 10.87075138092041\n",
      "NFAT-related_1_merged calculation time: 12.629904985427856\n",
      "MybSANT_1_merged calculation time: 14.917730569839478\n",
      "NF-kappaB-related_2_merged calculation time: 13.252447843551636\n",
      "More_5_merged calculation time: 15.8856520652771\n",
      "NK-related_2_merged calculation time: 10.048829317092896\n",
      "NR4A2 calculation time: 8.335564613342285\n",
      "More_2_merged calculation time: 20.393628120422363\n",
      "Nkx2-5 calculation time: 10.035863399505615\n",
      "NFYB calculation time: 14.293105363845825\n",
      "NR2F1 calculation time: 12.278860330581665\n",
      "NFYA calculation time: 15.997754096984863\n",
      "NFIC::TLX1 calculation time: 17.032479763031006\n",
      "Nuclear_1_merged calculation time: 8.130784273147583\n",
      "Nr2e1 calculation time: 9.15376877784729\n",
      "NK-related_1_merged calculation time: 15.485822200775146\n",
      "Nfe2l2 calculation time: 13.398221015930176\n",
      "Nr2e3 calculation time: 9.926300525665283\n",
      "NRF1 calculation time: 14.194085359573364\n",
      "Nkx2-5_var.2 calculation time: 12.532249450683594\n",
      "PAS_1_merged calculation time: 11.876907110214233\n",
      "Paired-related_2_merged calculation time: 10.477577209472656\n",
      "PBX1 calculation time: 13.46355128288269\n",
      "PLAG1 calculation time: 13.340071678161621\n",
      "PROX1 calculation time: 12.245702505111694\n",
      "POU_2_merged calculation time: 14.96565580368042\n",
      "Pax2 calculation time: 9.289303302764893\n",
      "PAX5 calculation time: 16.85992980003357\n",
      "POU_1_merged calculation time: 16.06618332862854\n",
      "POU6F2 calculation time: 16.479188442230225\n",
      "Paired_1_merged calculation time: 11.173808097839355\n",
      "Paired-related_1_merged calculation time: 15.46559453010559\n",
      "PRDM1 calculation time: 15.898690700531006\n",
      "Paired-related_4_merged calculation time: 12.614948749542236\n",
      "Nr1h3::Rxra calculation time: 20.870553016662598\n",
      "POU_3_merged calculation time: 17.414528608322144\n",
      "Nr5a2 calculation time: 20.932834148406982\n",
      "Paired-related_5_merged calculation time: 14.510987281799316\n",
      "Pax6 calculation time: 12.881525754928589\n",
      "Paired_2_merged calculation time: 15.131053924560547\n",
      "Pou5f1::Sox2 calculation time: 14.870454788208008\n",
      "RFX-related_1_merged calculation time: 14.906736135482788\n",
      "PPARG calculation time: 21.504412174224854\n",
      "Paired-related_3_merged calculation time: 19.900618076324463\n",
      "RORA calculation time: 15.459957361221313\n",
      "RUNX1 calculation time: 12.769593000411987\n",
      "REST calculation time: 18.316057920455933\n",
      "SOX10 calculation time: 8.202696323394775\n",
      "Runt-related_1_merged calculation time: 10.109199047088623\n",
      "SOX-related_2_merged calculation time: 9.612619400024414\n",
      "RXR-related_1_merged calculation time: 14.73776650428772\n",
      "RXRA::VDR calculation time: 14.133794784545898\n",
      "RXR-related_3_merged calculation time: 15.558097124099731\n",
      "RORA_var.2 calculation time: 20.8480966091156\n",
      "SPIB calculation time: 10.662707567214966\n",
      "Sox17 calculation time: 7.972777605056763\n",
      "Rhox11 calculation time: 14.743467092514038\n",
      "Regulators_1_merged calculation time: 14.761614322662354\n",
      "SOX-related_3_merged calculation time: 13.765631198883057\n",
      "SOX-related_1_merged calculation time: 15.891245603561401\n",
      "STAT1::STAT2 calculation time: 13.626431703567505\n",
      "Spz1 calculation time: 10.700029373168945\n",
      "SPDEF calculation time: 15.967313528060913\n",
      "SMAD3 calculation time: 17.37386989593506\n",
      "TALE-type_2_merged calculation time: 9.005033254623413\n",
      "TAL1::TCF3 calculation time: 11.146457433700562\n",
      "RREB1 calculation time: 26.445830583572388\n",
      "SMAD2::SMAD3::SMAD4 calculation time: 19.28745746612549\n",
      "Six3 calculation time: 14.876542329788208\n",
      "TALE-type_1_merged calculation time: 11.318609952926636\n",
      "STAT_1_merged calculation time: 18.158339977264404\n",
      "SRF calculation time: 18.977872371673584\n",
      "Steroid_3_merged calculation time: 14.155774116516113\n",
      "THAP1 calculation time: 9.074869394302368\n",
      "TBrain-related_1_merged calculation time: 11.713814973831177\n",
      "RXR-related_2_merged calculation time: 26.048656702041626\n",
      "TBP calculation time: 13.267855405807495\n",
      "TEF-1-related_1_merged calculation time: 11.498234033584595\n",
      "Tal-related_2_merged calculation time: 10.844539403915405\n",
      "TCF-7-related_1_merged calculation time: 12.982280015945435\n",
      "Tal-related_1_merged calculation time: 13.616748332977295\n",
      "Steroid_2_merged calculation time: 21.398091316223145\n",
      "YY1 calculation time: 11.211282968521118\n",
      "YY2 calculation time: 11.21870470046997\n",
      "Three-zinc_1_merged calculation time: 15.034210205078125\n",
      "XBP1 calculation time: 12.579271793365479\n",
      "ZEB1 calculation time: 9.592006921768188\n",
      "Steroid_1_merged calculation time: 23.364699602127075\n",
      "ZNF354C calculation time: 8.621228218078613\n",
      "Three-zinc_2_merged calculation time: 16.627615690231323\n",
      "ZBED1 calculation time: 13.323817014694214\n",
      "Vdr calculation time: 15.093983888626099\n",
      "ZBTB18 calculation time: 13.732929944992065\n",
      "Three-zinc_3_merged calculation time: 18.158801794052124\n",
      "TP53 calculation time: 20.44325089454651\n",
      "ZNF740 calculation time: 11.419802904129028\n",
      "ZNF143 calculation time: 13.933303117752075\n",
      "bHLH-ZIP_1_merged calculation time: 11.679265975952148\n",
      "Zfx calculation time: 12.557470321655273\n",
      "ZBTB7A calculation time: 15.191152095794678\n",
      "Znf423 calculation time: 13.326685667037964\n",
      "ZBTB33 calculation time: 16.79024910926819\n",
      "ZNF263 calculation time: 17.00981855392456\n",
      "ZNF410 calculation time: 16.917346000671387\n",
      "p53-related_1_merged calculation time: 15.570869445800781\n",
      "total time 110.1121473312378\n"
     ]
    }
   ],
   "source": [
    "# calculate motif scores\n",
    "!rm -r ./motif_scores\n",
    "!/gpfs/data01/glasslab/home/jtao/code/tba/model_training/calculate_all_motif_scores.py -num_procs 28 ./merged_atac_peaks_filtered_resized.fasta ./motif_scores /gpfs/data01/glasslab/home/jtao/code/tba/default_motifs/*jaspar"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Top Motif Scores"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 124,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "rm: cannot remove ‘./motif_scores’: No such file or directory\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "Arid3a calculation time: 7.423861026763916\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "Ahr::Arnt calculation time: 8.281291723251343\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "CREB1 calculation time: 9.059847831726074\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "Dux calculation time: 9.281664609909058\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "CEBP-related_2_merged calculation time: 10.874114513397217\n",
      "Arid3b calculation time: 12.070955514907837\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "CEBP-related_1_merged calculation time: 11.59044885635376\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "BARHL2 calculation time: 12.433391809463501\n",
      "DMRT3 calculation time: 11.33101224899292\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "CP2-related_1_merged calculation time: 12.220287561416626\n",
      "E2F-related_1_merged calculation time: 11.3313307762146\n",
      "AP-2_1_merged calculation time: 14.446853160858154\n",
      "Ddit3::Cebpa calculation time: 11.823503732681274\n",
      "CREB-related_1_merged calculation time: 12.369780778884888\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "CEBPA calculation time: 12.938252210617065\n",
      "AP-2_2_merged calculation time: 14.765891551971436\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "Arid5a calculation time: 14.486951112747192\n",
      "E2F1 calculation time: 11.853878259658813\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "/gpfs/data01/glasslab/home/jtao/software/anaconda3/lib/python3.5/site-packages/numpy/core/_methods.py:26: RuntimeWarning: invalid value encountered in reduce\n",
      "  return umr_maximum(a, axis, None, out, keepdims)\n",
      "E2F-related_3_merged calculation time: 12.576972246170044\n",
      "Bcl6 calculation time: 14.67138385772705\n",
      "CENPB calculation time: 14.686920881271362\n",
      "ATF4 calculation time: 17.270787477493286\n",
      "EBF1 calculation time: 14.47902798652649\n",
      "Bach1::Mafk calculation time: 17.072416305541992\n",
      "E2F-related_2_merged calculation time: 15.921144723892212\n",
      "BCL6B calculation time: 18.2901611328125\n",
      "Brachyury-related_1_merged calculation time: 18.73102378845215\n",
      "CTCF calculation time: 19.75308346748352\n",
      "EGR1 calculation time: 15.240121603012085\n",
      "FOXH1 calculation time: 11.092013120651245\n",
      "GMEB2 calculation time: 9.559013366699219\n",
      "Ets-related_1_merged calculation time: 13.579509258270264\n",
      "HD-CUT_1_merged calculation time: 10.037622690200806\n",
      "GCM_1_merged calculation time: 11.558266401290894\n",
      "Factors_1_merged calculation time: 13.522577285766602\n",
      "Foxq1 calculation time: 12.225178241729736\n",
      "GLI2 calculation time: 11.88612961769104\n",
      "Forkhead_1_merged calculation time: 14.070868730545044\n",
      "Ets-related_2_merged calculation time: 15.113399744033813\n",
      "Gabpa calculation time: 12.351039171218872\n",
      "EWSR1-FLI1 calculation time: 19.216081857681274\n",
      "Gfi1b calculation time: 12.46713399887085\n",
      "HLTF calculation time: 10.745742321014404\n",
      "GATA-type_1_merged calculation time: 14.26582384109497\n",
      "Foxd3 calculation time: 15.809844017028809\n",
      "HMBOX1 calculation time: 12.20764422416687\n",
      "HOX-related_1_merged calculation time: 11.280041694641113\n",
      "HINFP calculation time: 14.072157144546509\n",
      "HD-CUT_2_merged calculation time: 14.923177242279053\n",
      "Gfi1 calculation time: 15.789849758148193\n",
      "GATA1::TAL1 calculation time: 16.70964217185974\n",
      "HOXA5 calculation time: 9.121443033218384\n",
      "Gmeb1 calculation time: 16.61848497390747\n",
      "HOX-related_3_merged calculation time: 14.191692113876343\n",
      "HNF4G calculation time: 16.49575185775757\n",
      "HOX-related_4_merged calculation time: 12.966533660888672\n",
      "HOX-related_2_merged calculation time: 15.253873348236084\n",
      "Jun-related_1_merged calculation time: 8.123309850692749\n",
      "Hand1::Tcf3 calculation time: 11.039968013763428\n",
      "Hairy-related_1_merged calculation time: 12.232390642166138\n",
      "MAFG::NFE2L1 calculation time: 6.868098020553589\n",
      "MZF1 calculation time: 7.358828783035278\n",
      "HSF_1_merged calculation time: 14.80085277557373\n",
      "INSM1 calculation time: 12.494301080703735\n",
      "LIN54 calculation time: 11.136974096298218\n",
      "Jun-related_2_merged calculation time: 12.02811312675476\n",
      "Hes2 calculation time: 14.459352731704712\n",
      "Lhx3 calculation time: 12.816643953323364\n",
      "Hoxd8 calculation time: 16.107223749160767\n",
      "Klf12 calculation time: 14.651621580123901\n",
      "MZF1_var.2 calculation time: 11.965757131576538\n",
      "Interferon-regulatory_1_merged calculation time: 16.191153049468994\n",
      "MAF::NFE2 calculation time: 14.467156410217285\n",
      "MTF1 calculation time: 13.41597843170166\n",
      "More_3_merged calculation time: 10.002804279327393\n",
      "More_1_merged calculation time: 12.843438863754272\n",
      "Hnf4a calculation time: 20.22703766822815\n",
      "Myb calculation time: 10.652337789535522\n",
      "Mecom calculation time: 14.649834156036377\n",
      "IRF1 calculation time: 20.824495553970337\n",
      "IRF2 calculation time: 21.133835554122925\n",
      "NF-kappaB-related_2_merged calculation time: 10.818601131439209\n",
      "MAFG calculation time: 19.193389415740967\n",
      "More_5_merged calculation time: 14.978793859481812\n",
      "MybSANT_1_merged calculation time: 14.116234302520752\n",
      "NFAT-related_1_merged calculation time: 10.821779727935791\n",
      "Maf-related_1_merged calculation time: 19.05494976043701\n",
      "NF-kappaB-related_1_merged calculation time: 13.29121708869934\n",
      "Myod1 calculation time: 14.274043798446655\n",
      "NFIL3 calculation time: 12.32672929763794\n",
      "More_4_merged calculation time: 18.1779842376709\n",
      "NFIC::TLX1 calculation time: 14.2691650390625\n",
      "NK-related_2_merged calculation time: 11.336138248443604\n",
      "NR4A2 calculation time: 10.311110019683838\n",
      "More_2_merged calculation time: 20.579330921173096\n",
      "MyoD_1_merged calculation time: 18.205156803131104\n",
      "Nkx2-5 calculation time: 10.19593095779419\n",
      "NFYB calculation time: 14.390345335006714\n",
      "Nr2e3 calculation time: 8.851827383041382\n",
      "NR2F1 calculation time: 13.660290718078613\n",
      "Nuclear_1_merged calculation time: 9.05753493309021\n",
      "Nkx2-5_var.2 calculation time: 11.929914474487305\n",
      "Nr2e1 calculation time: 11.47583818435669\n",
      "NFYA calculation time: 18.091051816940308\n",
      "Nfe2l2 calculation time: 14.827065467834473\n",
      "NK-related_1_merged calculation time: 17.78187918663025\n",
      "POU6F2 calculation time: 11.425310134887695\n",
      "Nr5a2 calculation time: 15.018579483032227\n",
      "PBX1 calculation time: 12.610950231552124\n",
      "PAS_1_merged calculation time: 13.274818658828735\n",
      "NRF1 calculation time: 20.036091327667236\n",
      "PLAG1 calculation time: 14.94679069519043\n",
      "Pax2 calculation time: 8.222384929656982\n",
      "Paired-related_2_merged calculation time: 11.453943967819214\n",
      "Paired-related_4_merged calculation time: 10.844382762908936\n",
      "PAX5 calculation time: 17.330318450927734\n",
      "Nr1h3::Rxra calculation time: 20.605740785598755\n",
      "Paired_1_merged calculation time: 11.186978578567505\n",
      "Paired-related_5_merged calculation time: 12.441040515899658\n",
      "POU_2_merged calculation time: 16.501733779907227\n",
      "Paired-related_1_merged calculation time: 15.309900760650635\n",
      "PPARG calculation time: 18.18992805480957\n",
      "POU_1_merged calculation time: 20.06821346282959\n",
      "Paired-related_3_merged calculation time: 15.610091924667358\n",
      "PROX1 calculation time: 16.972904920578003\n",
      "POU_3_merged calculation time: 18.936161756515503\n",
      "PRDM1 calculation time: 18.028198957443237\n",
      "RORA calculation time: 12.11786699295044\n",
      "Paired_2_merged calculation time: 16.983617782592773\n",
      "Pax6 calculation time: 16.22034239768982\n",
      "RFX-related_1_merged calculation time: 15.031972169876099\n",
      "Pou5f1::Sox2 calculation time: 16.500063180923462\n",
      "REST calculation time: 18.750373125076294\n",
      "RUNX1 calculation time: 14.122175216674805\n",
      "SOX10 calculation time: 7.413171768188477\n",
      "Runt-related_1_merged calculation time: 10.728713274002075\n",
      "RORA_var.2 calculation time: 16.695709466934204\n",
      "RXR-related_2_merged calculation time: 15.62774109840393\n",
      "SMAD3 calculation time: 11.389509439468384\n",
      "SOX-related_3_merged calculation time: 10.786545038223267\n",
      "RXRA::VDR calculation time: 14.085757732391357\n",
      "RXR-related_1_merged calculation time: 16.631097078323364\n",
      "Regulators_1_merged calculation time: 14.270243883132935\n",
      "SPIB calculation time: 8.61899471282959\n",
      "SMAD2::SMAD3::SMAD4 calculation time: 12.86681580543518\n",
      "SOX-related_2_merged calculation time: 12.258561134338379\n",
      "Sox17 calculation time: 9.140317916870117\n",
      "RREB1 calculation time: 19.349361896514893\n",
      "RXR-related_3_merged calculation time: 18.74994206428528\n",
      "Rhox11 calculation time: 16.256985425949097\n",
      "SOX-related_1_merged calculation time: 16.03621220588684\n",
      "STAT_1_merged calculation time: 14.125040054321289\n",
      "SPDEF calculation time: 15.140925884246826\n",
      "Steroid_3_merged calculation time: 11.357147693634033\n",
      "STAT1::STAT2 calculation time: 15.427264213562012\n",
      "TALE-type_2_merged calculation time: 9.278403759002686\n",
      "Spz1 calculation time: 13.856719732284546\n",
      "SRF calculation time: 16.242632389068604\n",
      "Six3 calculation time: 16.479363203048706\n",
      "TAL1::TCF3 calculation time: 11.462883710861206\n",
      "TALE-type_1_merged calculation time: 12.884661674499512\n",
      "TBrain-related_1_merged calculation time: 12.461408615112305\n",
      "Steroid_1_merged calculation time: 16.91528606414795\n",
      "TEF-1-related_1_merged calculation time: 11.557485818862915\n",
      "Steroid_2_merged calculation time: 17.45809268951416\n",
      "TBP calculation time: 14.36468768119812\n",
      "THAP1 calculation time: 12.754770994186401\n",
      "TCF-7-related_1_merged calculation time: 14.460945844650269\n",
      "Tal-related_1_merged calculation time: 14.19420313835144\n",
      "YY2 calculation time: 11.323360204696655\n",
      "Three-zinc_2_merged calculation time: 14.460937976837158\n",
      "Three-zinc_3_merged calculation time: 14.510900259017944\n",
      "XBP1 calculation time: 13.524385690689087\n",
      "TP53 calculation time: 16.182210206985474\n",
      "Three-zinc_1_merged calculation time: 15.871357679367065\n",
      "ZBED1 calculation time: 12.411345481872559\n",
      "ZNF354C calculation time: 8.37308955192566\n",
      "Vdr calculation time: 15.419919967651367\n",
      "Tal-related_2_merged calculation time: 16.886451482772827\n",
      "YY1 calculation time: 14.594571828842163\n",
      "ZBTB18 calculation time: 12.010286331176758\n",
      "ZEB1 calculation time: 11.45627236366272\n",
      "ZBTB7A calculation time: 12.340054035186768\n",
      "ZNF740 calculation time: 10.182432651519775\n",
      "ZBTB33 calculation time: 14.298541784286499\n",
      "bHLH-ZIP_1_merged calculation time: 9.991489887237549\n",
      "ZNF143 calculation time: 14.547476768493652\n",
      "ZNF410 calculation time: 14.82926058769226\n",
      "Zfx calculation time: 13.08952283859253\n",
      "Znf423 calculation time: 13.533980369567871\n",
      "ZNF263 calculation time: 18.023083925247192\n",
      "p53-related_1_merged calculation time: 15.680184841156006\n",
      "total time 158.73677134513855\n"
     ]
    }
   ],
   "source": [
    "# calculate motif scores\n",
    "!rm -r ./motif_scores\n",
    "!/gpfs/data01/glasslab/home/jtao/code/tba/model_training/calculate_motif_scores_biopython.py -num_procs 28 ./merged_atac_peaks_filtered_resized.fasta ./top_motif_scores /gpfs/data01/glasslab/home/jtao/code/tba/default_motifs/*jaspar"
   ]
  }
 ],
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