diff --git a/setup.py b/setup.py
index 69ae522464..ab5c0f3a73 100644
--- a/setup.py
+++ b/setup.py
@@ -81,7 +81,7 @@ def open_local(paths, mode="r", encoding="utf8"):
     '; sys_platform != "win32" ' 'and implementation_name == "cpython"'
 )
 ujson = "ujson>=1.35" + env_dependency
-uvloop = "uvloop>=0.5.3,!=0.15.0,!=0.15.1" + env_dependency
+uvloop = "uvloop>=0.5.3" + env_dependency
 
 requirements = [
     "httptools>=0.0.10",