diff --git a/src/main/java/org/springframework/data/redis/cache/RedisCacheManager.java b/src/main/java/org/springframework/data/redis/cache/RedisCacheManager.java
index c2ddb1c63f..18f26a4940 100644
--- a/src/main/java/org/springframework/data/redis/cache/RedisCacheManager.java
+++ b/src/main/java/org/springframework/data/redis/cache/RedisCacheManager.java
@@ -41,6 +41,7 @@
  *
  * @author Christoph Strobl
  * @author Mark Paluch
+ * @author Yanming Zhou
  * @since 2.0
  * @see RedisCacheConfiguration
  * @see RedisCacheWriter
@@ -336,6 +337,15 @@ public RedisCacheManagerBuilder cacheDefaults(RedisCacheConfiguration defaultCac
 			return this;
 		}
 
+		/**
+		 * Returns applied {@link RedisCacheConfiguration}, allow customization base on it.
+		 *
+		 * @return applied {@link RedisCacheConfiguration}.
+		 */
+		public RedisCacheConfiguration cacheDefaults() {
+			return this.defaultCacheConfiguration;
+		}
+
 		/**
 		 * Configure a {@link RedisCacheWriter}.
 		 *
diff --git a/src/test/java/org/springframework/data/redis/cache/RedisCacheManagerUnitTests.java b/src/test/java/org/springframework/data/redis/cache/RedisCacheManagerUnitTests.java
index 1160993463..70d0a72807 100644
--- a/src/test/java/org/springframework/data/redis/cache/RedisCacheManagerUnitTests.java
+++ b/src/test/java/org/springframework/data/redis/cache/RedisCacheManagerUnitTests.java
@@ -18,6 +18,7 @@
 import static org.assertj.core.api.Assertions.*;
 import static org.mockito.Mockito.*;
 
+import java.time.Duration;
 import java.util.Collections;
 
 import org.junit.jupiter.api.Test;
@@ -34,6 +35,7 @@
  *
  * @author Christoph Strobl
  * @author Mark Paluch
+ * @author Yanming Zhou
  */
 @ExtendWith(MockitoExtension.class)
 class RedisCacheManagerUnitTests {
@@ -188,4 +190,16 @@ void builderWontSetStatisticsCollectorByDefault() {
 
 		verify(cacheWriter, never()).withStatisticsCollector(any());
 	}
+
+	@Test // DATAREDIS-481
+	void customizeRedisCacheConfigurationBaseOnApplied() {
+
+		RedisCacheConfiguration configuration = RedisCacheConfiguration.defaultCacheConfig().disableKeyPrefix();
+		RedisCacheManagerBuilder cmb = RedisCacheManager.builder().cacheDefaults(configuration);
+
+		cmb.cacheDefaults(cmb.cacheDefaults().entryTtl(Duration.ofSeconds(10)));
+
+		assertThat(cmb.cacheDefaults().usePrefix()).isFalse();
+		assertThat(cmb.cacheDefaults().getTtl()).isEqualTo(Duration.ofSeconds(10));
+	}
 }