LLOQPATTERNS from Model Configuration Template not implemented

[tensfeldt]

Refer to openNCA Computation Engine Specifications Documentation for details.

LLOQPATTERNS setting defines a pattern, default defined as "LLOQ|BLQ|^[<]{1}", that is used to identify concentration data values that are below the lower limit of quantification. Currently MCT uses CONC and CONCRAW setting to identify the columns of data in the input concentration dataset that represent the numeric value of the concentration and the raw or character value of the concentration dataset. This approach is to allow the character value to incorporate values that are LLOQ/BLQ for traceability of the original data while using a transformed value (by default currently zero (0)) as the numeric equivalent for LLOQ/BLQ.

To this point, at time of this issue creation released version of openNCA CE is 3.0.2 (not yet tagged in Github), LLOQPATTERNS is not implemented. Recommend that implementation allows direct use of character values of the concentration replacing values matched to the pattern defined in LLOQPATTERNS to a zero value. Future development should allow for provision of a "procedure" that would impute the concentration to a different default.

[tensfeldt]

Issue is addressed/implemented in openNCA CE release 3.0.3 (not yet committed to repo - will update comment when git history cleaned up and pushed)