diff --git a/compiler/rustc_target/src/spec/targets/mips64_openwrt_linux_musl.rs b/compiler/rustc_target/src/spec/targets/mips64_openwrt_linux_musl.rs
index e83a43c1df257..b7415bf683de2 100644
--- a/compiler/rustc_target/src/spec/targets/mips64_openwrt_linux_musl.rs
+++ b/compiler/rustc_target/src/spec/targets/mips64_openwrt_linux_musl.rs
@@ -20,7 +20,7 @@ pub(crate) fn target() -> Target {
             std: None, // ?
         },
         pointer_width: 64,
-        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64".into(),
         options: TargetOptions {
             abi: "abi64".into(),
diff --git a/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_gnuabi64.rs b/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_gnuabi64.rs
index 252d614e9ac9d..75da4abc6b603 100644
--- a/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_gnuabi64.rs
+++ b/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_gnuabi64.rs
@@ -11,7 +11,7 @@ pub(crate) fn target() -> Target {
             std: Some(true),
         },
         pointer_width: 64,
-        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64".into(),
         options: TargetOptions {
             abi: "abi64".into(),
diff --git a/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_muslabi64.rs b/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_muslabi64.rs
index a1a596c9f1bc9..69af2da11001b 100644
--- a/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_muslabi64.rs
+++ b/compiler/rustc_target/src/spec/targets/mips64_unknown_linux_muslabi64.rs
@@ -16,7 +16,7 @@ pub(crate) fn target() -> Target {
             std: Some(true),
         },
         pointer_width: 64,
-        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64".into(),
         options: TargetOptions {
             abi: "abi64".into(),
diff --git a/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_gnuabi64.rs b/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_gnuabi64.rs
index 35d2911fa9d6b..c7d2487122529 100644
--- a/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_gnuabi64.rs
+++ b/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_gnuabi64.rs
@@ -10,7 +10,7 @@ pub(crate) fn target() -> Target {
             std: Some(true),
         },
         pointer_width: 64,
-        data_layout: "e-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "e-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64".into(),
         options: TargetOptions {
             abi: "abi64".into(),
diff --git a/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_muslabi64.rs b/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_muslabi64.rs
index 9dab932aed408..4f50e8b7033aa 100644
--- a/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_muslabi64.rs
+++ b/compiler/rustc_target/src/spec/targets/mips64el_unknown_linux_muslabi64.rs
@@ -15,7 +15,7 @@ pub(crate) fn target() -> Target {
             std: Some(true),
         },
         pointer_width: 64,
-        data_layout: "e-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "e-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64".into(),
         options: TargetOptions { abi: "abi64".into(), mcount: "_mcount".into(), ..base },
     }
diff --git a/compiler/rustc_target/src/spec/targets/mipsisa64r6_unknown_linux_gnuabi64.rs b/compiler/rustc_target/src/spec/targets/mipsisa64r6_unknown_linux_gnuabi64.rs
index 89ba7b889ec85..c5948b745ff59 100644
--- a/compiler/rustc_target/src/spec/targets/mipsisa64r6_unknown_linux_gnuabi64.rs
+++ b/compiler/rustc_target/src/spec/targets/mipsisa64r6_unknown_linux_gnuabi64.rs
@@ -11,7 +11,7 @@ pub(crate) fn target() -> Target {
             std: None, // ?
         },
         pointer_width: 64,
-        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "E-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64r6".into(),
         options: TargetOptions {
             abi: "abi64".into(),
diff --git a/compiler/rustc_target/src/spec/targets/mipsisa64r6el_unknown_linux_gnuabi64.rs b/compiler/rustc_target/src/spec/targets/mipsisa64r6el_unknown_linux_gnuabi64.rs
index 195894d9aac4d..60bda7a5996c7 100644
--- a/compiler/rustc_target/src/spec/targets/mipsisa64r6el_unknown_linux_gnuabi64.rs
+++ b/compiler/rustc_target/src/spec/targets/mipsisa64r6el_unknown_linux_gnuabi64.rs
@@ -10,7 +10,7 @@ pub(crate) fn target() -> Target {
             std: Some(true),
         },
         pointer_width: 64,
-        data_layout: "e-m:e-i8:8:32-i16:16:32-i64:64-n32:64-S128".into(),
+        data_layout: "e-m:e-i8:8:32-i16:16:32-i64:64-i128:128-n32:64-S128".into(),
         arch: "mips64r6".into(),
         options: TargetOptions {
             abi: "abi64".into(),