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Copyright (C) 2018-2021 RISE Research Institute of Sweden AB | ||
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MIT License | ||
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Permission is hereby granted, free of charge, to any person obtaining | ||
a copy of this software and associated documentation files (the | ||
"Software"), to deal in the Software without restriction, including | ||
without limitation the rights to use, copy, modify, merge, publish, | ||
distribute, sublicense, and/or sell copies of the Software, and to | ||
permit persons to whom the Software is furnished to do so, subject to | ||
the following conditions: | ||
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The above copyright notice and this permission notice shall be | ||
included in all copies or substantial portions of the Software. | ||
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THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, | ||
EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF | ||
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND | ||
NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE | ||
LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION | ||
OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION | ||
WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. | ||
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This repository contains the code used for data analysis in the BONSAI | ||
project (Financed by the Swedish funding agency Vinnova, 2018 - 2020). | ||
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The objective of the project was to explore methods for causal | ||
inference for finding causal links between child cancer treatment and | ||
late effects. The idea is to use a constraint based causal inference | ||
method adapted for small data sets (most medical data sets are small | ||
from a machine learning perspective), to distinguish whether a late | ||
effect is caused by personal predisposition, the primary cancer | ||
diagnosis, or one of the treatments for the cancer. | ||
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This repository contains two parts. One part contains the code for | ||
arranging the data from several registers (person info, control person | ||
info, diagnosis, treatments, in-patient care registry, out-patient | ||
care registry, death registry, and drug prescription, into a common | ||
file with all information about a patient or control person on one | ||
line each. The other part contains the analysis and visualization code | ||
based on that common file. | ||
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The actual data is not included here, since it contains sensitive | ||
personal information and is therefore not publicly available. | ||
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All the code is "research project quality", not production quality, | ||
which means that it is patchy, inconsistent, unclearn, not well | ||
documented, and thus not easy to use by someone else. Neverthelsee, it | ||
is included here for transparency of the methods used in the project. | ||
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For questions about the code and how to use reuse snippets of it in | ||
other projects, contact Anders Holst: anders.holst@ri.se | ||
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For questions about availability of data, contact Helena Linge: | ||
helena.linge@med.lu.se | ||
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For suggestion for future research collaboration around these issues, | ||
you can contact any of the above. |
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""" | ||
Copyright (C) 2018-2021 RISE Research Institute of Sweden AB | ||
File: Color.py | ||
Author: anders.holst@ri.se | ||
""" | ||
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import numpy as np | ||
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def colorgamma(x): | ||
if x < 0.0031308: | ||
return x*12.92 | ||
else: | ||
return 1.055 * np.power(x, 0.416667) - 0.055 | ||
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def invcolorgamma(x): | ||
if x < 0.04045: | ||
return x / 12.92 | ||
else: | ||
return np.power((x + 0.055)/1.055, 2.4) | ||
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def rgb_color(r, g, b): | ||
return tuple(list(map(colorgamma, [r,g,b]))) | ||
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# mimics color.scm with 6color, bluebased, and smooth | ||
def hsl_color(h, s, l): | ||
hramp = [0, 1/12, 1/6, 1/3, 2/3, 7/9, 1] | ||
iramp = [(2.410996, 0.16, 0, 0, 1), (0.862552, 0.79, 0, 1, 1), | ||
(-0.252442, 0.63, 0, 1, 0), (-1.981885, 0.84, 1, 1, 0), | ||
(1.786451, 0.21, 1, 0, 0), (1.571190, 0.37, 1, 0, 1), | ||
(2.410996, 0.16, 0, 0, 1)] | ||
i = 0 | ||
while h > hramp[i+1]: | ||
i += 1 | ||
p = (h - hramp[i])/(hramp[i+1] - hramp[i]) | ||
(a, br, r, g, b) = tuple(map(lambda x1, x2: p*(x2 - x1) + x1, iramp[i], iramp[i+1])) | ||
ll0 = (l + 1.0)*0.5 | ||
ll = (np.exp(a*ll0) - 1.0)/(np.exp(a) - 1.0) if not a==0 else ll0 | ||
if ll < br: | ||
t1 = s * ll / br | ||
t2 = ll0 * (1.0 - s) | ||
else: | ||
t1 = s * (1.0 - ll) / (1.0 - br) | ||
t2 = ll0 * (1.0 - s) + s * (ll - br) / (1.0 - br) | ||
return rgb_color(r*t1+t2, g*t1+t2, b*t1+t2) | ||
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def gencolor(light=0.0, starthue=0.0, startsat=1.0, unsat=False): | ||
h = starthue | ||
s = startsat | ||
if unsat: | ||
ss = s*s | ||
l = light | ||
gs1 = (3.0 - np.sqrt(5))/2.0 | ||
gs2 = gs1/np.sqrt(3) | ||
while True: | ||
yield hsl_color(h, s, l) | ||
h -= gs1 | ||
if h < 0.0: | ||
h += 1.0 | ||
if unsat: | ||
ss -= gs2 | ||
if ss <= 0: | ||
ss += 1.0 | ||
s = np.sqrt(ss) | ||
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