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This repository contains version 1 of the "ClinSig" program, a Shiny application developed in RStudio that visualizes clinical variants from the NCBI ClinVar database in a lollipop plot format according to their clinical significance.

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ClinSig-V1

This repository contains version 1 of the "ClinSig" program, a Shiny application developed in RStudio that visualizes clinical variants from the NCBI ClinVar database in a lollipop plot format according to their clinical significance.

How to Use?

  1. Search ClinVar database for the gene of clinical interest and download all variants as a text file.

  2. Load required R libraries.

  3. Run the data_manipulation.R script to select the text file and generate a my_data.csv file.

  4. Load libraries again and run the Lollipop_plot_shiny.R script.

  5. In the Shiny app screen, upload the my_data.csv file and click submit to generate an interactive lollipop plot of the variants.

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This repository contains version 1 of the "ClinSig" program, a Shiny application developed in RStudio that visualizes clinical variants from the NCBI ClinVar database in a lollipop plot format according to their clinical significance.

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