Reproduction

This section reproduces the output of [GuiltyTargets paper](https://www.biorxiv.org/content/10 .1101/521161v1).

Due to licencing reasons, analyses that use TTD drug targets and Alzheimer's disease data sets are removed from this reproduction.

Requirements

You will need Python 3.7+ and R 3.6.0+ to run the program.

Required R packages are: Bioconductor Biobase GEOquery limma

To install the required Python libraries, you can run:

$ cd reproduction
$ pip install requirements.txt

Running

To run the code:

$ chmod +x run.sh
$ ./run.sh

Output

You can find the output under reproduction/data results.csv file gives an overview of all AUROC values under different settings.