Skip to content

Commit

Permalink
Update README.md
Browse files Browse the repository at this point in the history
  • Loading branch information
modupeore authored Feb 28, 2020
1 parent 5547989 commit 34103c3
Showing 1 changed file with 5 additions and 6 deletions.
11 changes: 5 additions & 6 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -3,7 +3,9 @@
Thank you for your interest in using the Variant Analysis Pipeline.
VAP is a comprehensive workflow for reference mapping and variant detection of genomic and transcriptomic reads using a suite of bioinformatics tools.

Article Source: Variant analysis pipeline for accurate detection of genomic variants from transcriptome sequencing data
_**Article Source:**_

Variant analysis pipeline for accurate detection of genomic variants from transcriptome sequencing data
Adetunji MO, Lamont SJ, Abasht B, Schmidt CJ (2019) Variant analysis pipeline for accurate detection of genomic variants from transcriptome sequencing data. PLOS ONE 14(9): e0216838. https://doi.org/10.1371/journal.pone.0216838


Expand All @@ -14,13 +16,11 @@ Bioinformatic tools are grouped based on sequencing reads
* BOWTIE2
* BWA


### Transcriptomic Sequencing
* TOPHAT2
* STAR (2-PASS)
* HISAT2


### Variant Calling (for both Genomic/Transcriptomic Sequencing)
* PICARD + GATK HaplotypeCaller
* sort, addreadgroups, markduplicates using **Picard Tools**.
Expand All @@ -29,7 +29,7 @@ Bioinformatic tools are grouped based on sequencing reads

**N.B.** : parameters of all tools are set to default.

Software used to design the VAP workflow are:
### Software used to design the VAP workflow are:

Software | Version
-------- | -------------
Expand All @@ -44,8 +44,7 @@ BOWTIE2 | 2.3.5.1

*Current pipeline is not compatible with GATK v4*

Contact maintainer to make custom changes to the different tools if needed.

Contact maintainer to make custom changes to the different tools


## Things to be aware of
Expand Down

0 comments on commit 34103c3

Please # to comment.