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Add PRSoS and imputation-prep pipelines #2

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Add PRSoS and imputation-prep pipelines #2

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@moldach moldach commented Sep 21, 2018

I've added two tools to your repo. One prepares PLINK files for imputation on the Sanger Imputation service the other is an alternative PRS tool that perform faster than PRSice. Furthermore, PRSice v1.25 discards strand-ambiguous SNPs whereas PRSoS includes the strand-ambiguous SNPs allowing researchers to retain as much information as possible from the discovery data, and likely give rise to a better understanding of the complex phenotypes.

Full disclosure: these tools were developed our lab (Dr. Micheal Meaney) at McGill.

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